儿童COVID-19临床和实验室结果评估:单中心经验

Nihan Uygur Klc, Ozlem Erdede, Erdal Sar, Rabia Gnl Sezer Yamanel
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摘要

尽管SARS-CoV-2在全球传播,但关于儿童特征的数据有限。我们的目的是阐明更好地理解儿童SARS-CoV-2感染的临床和实验室特征。从医疗记录中提取有关表现症状、暴露史、年龄、性别、合并症的存在、实验室数据、放射学结果(包括胸片)、治疗方式、住院需要和疾病严重程度的临床分类、住院时间的临床数据。本研究共纳入27例小儿COVID-19患者。男生15人,占55.5%。儿童平均年龄为6.3岁(范围为2个月-17岁)。6例患儿住院(22.2%),27例患儿中有15例(55.5%)出现血液学异常。所有患者均行x射线检查,27例患者中有7例出现异常(25.9%)。不同地区和国家的儿童在表现症状和临床特征上可能存在差异。本儿科临床报告增加了来自大流行中心土耳其伊斯坦布尔的数据,讨论了儿童的症状学和放射学发现。
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Evaluation of clinical and laboratory findings of pediatric COVID-19: A single-center experience
There is limited data regarding the features of SARS-CoV-2 in children despite the worldwide spread. We aimed to elucidate a better understanding of the clinical and laboratory features of SARS-CoV-2 infection in children. Clinical data about presenting symptoms, exposure history, age, gender, presence of comorbidities, laboratory data, radiological findings including chest radiographs, modalities of treatment, need for hospitalization and clinical classification of disease severity, length of admission were extracted from the medical records. A total of 27 pediatric patients with COVID-19 were included in this study. There were 15 boys, 55.5%. The mean age of children was 6.3 years (range= 2 months-17 years). Six children were hospitalized (22.2%), Hematological abnormalities were present in 15 out of 27 (55.5%) children. All patients got CXRs and 7 out of 27 had abnormal findings (25.9%). There may be differences in presenting symptoms and clinical features between children from different regions and countries. This pediatric clinical report adds data from the epicenter of pandemic in Turkey, Istanbul, discussing symptomatology and radiological findings in children.
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