MIRIAM机器人:一种用于磁共振引导前列腺穿刺的新型机器人系统

P. Moreira, Gert van de Steeg, Thijs Krabben, Jonathan Zandman, E. Hekman, F. Heijden, Ronald Borra, S. Misra
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引用次数: 39

摘要

前列腺癌的早期发现和治疗对降低死亡率具有重要意义。磁共振(MR)成像提供前列腺的图像,可以看到早期病变。使用机器人系统进行核磁共振引导的前列腺干预使我们能够改善活检和近距离放射治疗等手术的临床结果。这项工作提出了一个新的磁共振条件机器人前列腺干预。磁共振成像环境下的微创机器人(MIRIAM)机器人具有9个自由度(DoF),用于引导和发射活检针。导针器由压电电机驱动的5自由度并联机器人对会阴进行定位。在此过程中,一个4自由度的针驱动器插入、旋转和发射针。针的插入和旋转采用压电电机,射针采用气动驱动。给出了机器人的核磁共振条件设计和插针控制器设计。使用T2成像协议进行的磁共振兼容性测试显示,当机器人在磁共振扫描仪内操作时,信噪比降低了25%。在实验中,将活检针插入物理目标的平均瞄准误差为1.84mm。我们的研究提出了一种新的核磁共振条件机器人,并展示了在软组织幻影中进行核磁共振引导针基干预的能力。此外,图像畸变分析表明,机器人没有引起明显的图像劣化。
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The MIRIAM Robot: A Novel Robotic System for MR-Guided Needle Insertion in the Prostate
Early prostate cancer detection and treatment are of major importance to reduce mortality rate. magnetic resonance (MR) imaging provides images of the prostate where an early stage lesion can be visualized. The use of robotic systems for MR-guided interventions in the prostate allows us to improve the clinical outcomes of procedures such as biopsy and brachytherapy. This work presents a novel MR-conditional robot for prostate interventions. The minimally invasive robotics in an magnetic resonance imaging environment (MIRIAM) robot has 9 degrees-of-freedom (DoF) used to steer and fire a biopsy needle. The needle guide is positioned against the perineum by a 5 DoF parallel robot driven by piezoelectric motors. A 4 DoF needle driver inserts, rotates and fires the needle during the procedure. Piezoelectric motors are used to insert and rotate the needle, while pneumatic actuation is used to fire the needle. The MR-conditional design of the robot and the needle insertion controller are presented. MR compatibility tests using T2 imaging protocol are performed showing a SNR reduction of 25% when the robot is operational within the MR scanner. Experiments inserting a biopsy needle toward a physical target resulted in an average targeting error of 1.84mm. Our study presents a novel MR-conditional robot and demonstrated the ability to perform MR-guided needle-based interventions in soft-tissue phantoms. Moreover, the image distortion analysis indicates that no visible image deterioration is induced by the robot.
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