{"title":"Tardyferon治疗婴幼儿低铁血症。","authors":"K Horváth, G Horn","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In the majority of cases iron deficiency of infancy and early childhood is caused by nutritional factors. Among diseases, absorption disorders are the most frequent causes of iron deficiency. Tardyferon has been used for controlling iron deficiency in 21 children younger than two years of age not suffering from malabsorption and in 38 children suffering from coeliac disease. At the onset of the disease 71% of coeliac disease patients suffered from iron deficiency. The normalization of iron metabolism of these patients could be achieved with oral treatment of 5-6 mg Fe++/kg/day of 3-6 months. Iron deficiency of patients with initially normal ferritin level developed as a result of the intensive weight gain occurring in response to the gliadin-free diet. After the patients had been put on a gliadin containing diet again, hyposiderosis also occurred more frequently. Tardyferon therapy was well tolerated by the patients, in the infants taking bébé-Tardyferon difficulties of dosage or notable side-effects were not observed.</p>","PeriodicalId":76737,"journal":{"name":"Therapia Hungarica (English edition)","volume":"40 1","pages":"40-3"},"PeriodicalIF":0.0000,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Tardyferon therapy in hyposiderosis of infancy and childhood.\",\"authors\":\"K Horváth, G Horn\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>In the majority of cases iron deficiency of infancy and early childhood is caused by nutritional factors. Among diseases, absorption disorders are the most frequent causes of iron deficiency. Tardyferon has been used for controlling iron deficiency in 21 children younger than two years of age not suffering from malabsorption and in 38 children suffering from coeliac disease. At the onset of the disease 71% of coeliac disease patients suffered from iron deficiency. The normalization of iron metabolism of these patients could be achieved with oral treatment of 5-6 mg Fe++/kg/day of 3-6 months. Iron deficiency of patients with initially normal ferritin level developed as a result of the intensive weight gain occurring in response to the gliadin-free diet. After the patients had been put on a gliadin containing diet again, hyposiderosis also occurred more frequently. Tardyferon therapy was well tolerated by the patients, in the infants taking bébé-Tardyferon difficulties of dosage or notable side-effects were not observed.</p>\",\"PeriodicalId\":76737,\"journal\":{\"name\":\"Therapia Hungarica (English edition)\",\"volume\":\"40 1\",\"pages\":\"40-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1992-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Therapia Hungarica (English edition)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Therapia Hungarica (English edition)","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
在大多数情况下,婴幼儿缺铁是由营养因素引起的。在各种疾病中,吸收障碍是导致缺铁的最常见原因。Tardyferon已被用于控制21名两岁以下没有吸收不良的儿童和38名患有乳糜泻的儿童缺铁。在发病时,71%的乳糜泻患者缺铁。口服5-6 mg Fe++/kg/天,疗程3-6个月,可使患者铁代谢恢复正常。最初铁蛋白水平正常的患者的铁缺乏是由于对不含麦胶蛋白饮食的反应导致体重增加。在患者再次食用含麦胶蛋白的饮食后,低铁沉着的发生也更为频繁。患者对Tardyferon治疗耐受性良好,在婴儿中服用b b -Tardyferon,没有观察到剂量困难或明显的副作用。
Tardyferon therapy in hyposiderosis of infancy and childhood.
In the majority of cases iron deficiency of infancy and early childhood is caused by nutritional factors. Among diseases, absorption disorders are the most frequent causes of iron deficiency. Tardyferon has been used for controlling iron deficiency in 21 children younger than two years of age not suffering from malabsorption and in 38 children suffering from coeliac disease. At the onset of the disease 71% of coeliac disease patients suffered from iron deficiency. The normalization of iron metabolism of these patients could be achieved with oral treatment of 5-6 mg Fe++/kg/day of 3-6 months. Iron deficiency of patients with initially normal ferritin level developed as a result of the intensive weight gain occurring in response to the gliadin-free diet. After the patients had been put on a gliadin containing diet again, hyposiderosis also occurred more frequently. Tardyferon therapy was well tolerated by the patients, in the infants taking bébé-Tardyferon difficulties of dosage or notable side-effects were not observed.