重金属结合蛋白和多肽

Biopolymers Online Pub Date : 2003-01-27 DOI:10.1002/3527600035.BPOL8010

S. Clemens, C. Simm, T. Maier

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引用次数: 8

摘要

金属硫蛋白、植物螯合蛋白和植物螯合蛋白-金属配合物的化学结构、命名和结构金属伴侣蛋白的结构性质金属硫蛋白、植物螯合蛋白、金属硫蛋白、植物螯合蛋白、金属伴侣蛋白的化学分析和检测金属硫蛋白、植物螯合蛋白、金属硫蛋白、植物螯合蛋白、金属伴侣蛋白的功能金属稳态及其缓冲和解毒的作用生理金属硫蛋白定位和同工异构体定位和植物螯合蛋白合成的区隔生物化学金属硫蛋白的金属结合特性植物螯合蛋白合成的生物化学分子遗传学金属硫蛋白基因及其调控植物螯合蛋白合酶基因生物技术应用专利前景与展望关键词:金属硫蛋白;转移;metallochaperones;谷胱甘肽;代数余子式;重金属;重金属耐受性;重金属积累;重金属中毒;植物修复;金属交易;金属运输;阿尔茨海默病;朊病毒疾病;自闭症;锌;铁;铜;镉

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Heavy Metal‐binding Proteins and Peptides

Introduction Historical Outline Chemical Structures Nomenclature and Structure of Metallothioneins Phytochelatins and Phytochelatin–Metal Complexes Structural Properties of Metallochaperones Chemical Analysis and Detection Metallothioneins Phytochelatins Occurrence Metallothioneins Phytochelatins Metallochaperones Functions Metal Homeostasis and the Role of Metallochaperones Buffering and Detoxification Physiology Metallothionein Localization and Isoforms Localization and Compartmentation of Phytochelatin Synthesis Biochemistry Metal-binding Characteristics of Metallothioneins Biochemistry of Phytochelatin Synthesis Molecular Genetics Metallothionein Genes and Their Regulation Phytochelatin Synthase Genes Biotechnological Applications Patents Outlook and Perspectives Keywords: metallothioneins; phytochelatins; metallochaperones; glutathione; cofactor; heavy metal; heavy metal tolerance; heavy metal accumulation; heavy metal toxicity; phytoremediation; metal trafficking; metal transport; Alzheimer's disease; prion diseases; autism; zinc; iron; copper; cadmium

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