合作小组试验中Rappaport分类与工作公式之比较:ECOG经验。

Hematologic pathology Pub Date : 1992-01-01
R S Neiman, K Cain, Y Ben Arieh, D Harrington, R B Mann, B C Wolf
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引用次数: 0

摘要

在最初的研究中,用于非霍奇金淋巴瘤分类的工作公式(WF)被证明是可重复的和临床相关的。然而,nci支持的合作临床肿瘤学小组尚未对其进行测试。因此,东部肿瘤合作组织(ECOG)的血液病理学小组委员会进行了一项回顾性研究,比较WF和Rappaport分类(RC)的一致性和实用性。数据表明,通过适当的修改以尽量减少无法分类的淋巴瘤,WF可以有效地用于临床肿瘤合作组。
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A comparison between the Rappaport Classification and Working Formulation in cooperative group trials: the ECOG experience.

The Working Formulation (WF) for the classification of non-Hodgkin's lymphomas was shown to be reproducible and clinically relevant in the original study. However, it has not yet been tested by an NCI-supported cooperative clinical oncology group. As a result, the Hematopathology Subcommittee of the Eastern Cooperative Oncology Group (ECOG) undertook a retrospective study to compare concordance and practical utility between the WF and the Rappaport Classification (RC). Data indicate that with appropriate modifications to minimize unclassifiable lymphomas, the WF can be effectively utilized in cooperative clinical oncology groups.

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