血友病A型患者颅内出血的研究

N. S. Budi, P. Airlangga, B. Semedi
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摘要

简介:遗传性出血性疾病的颅内出血是一种急症。大多数儿童的出血部位在硬膜下,最常见的原因是血友病。虽然血友病患者颅内出血的发生率不到5%,但这是危及生命的医疗紧急情况,因此需要适当的治疗。病例报告:一名11岁,体重20公斤的男孩患者在家中癫痫发作,随后意识下降。发现异常表现为贫血、FH延长(PPT 4x和APTT 4x)和低钙血症。给予主治疗;FVIII按100 IU/dL的FVIII目标水平计算。按照FVIII 50IU/dL的每日目标,继续500IU/12小时的治疗。病人的情况一天比一天好。术后14天后患者意识开始好转。一个月后,患者作为发作性处理者接受koate治疗。诊断颅内出血患者的确切原因可以提供适当的治疗,从而帮助患者。结论:麻醉医师、神经外科医师和儿科医师之间的良好合作将提高重症出血无重大后遗症的成功率。
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Intracranial Hemorrhage in Patients With Hemophilia A
Introduction: Intracranial hemorrhage in inherited bleeding disorders is a medical emergency. The location of bleeding in most children is subdural and the most common cause is hemophilia. Although intracranial bleeding that occurs in people with hemophilia ranges from less than 5% of events, it is a life-threatening medical emergency so appropriate treatment is needed. Case Report: A boy patient 11 years old, 20kg weights have a seizure at home and followed by a decrease in consciousness. It was founded abnormalities in the form of anemia, prolonged FH (PPT 4x and APTT 4x), and hypocalcemia. The patient then was given main therapy; FVIII 100 IU/dL according to the FVIII target level calculated. The therapy continued with 500IU/12 hours according to the daily target of FVIII 50IU/dL. Discussion: The patient’s condition was getting better day by day. The patient’s consciousness started to improve after 14 days of postoperative. One month after that, the patient received koate treatment as the episodic handler. Diagnosing the exact cause in patients who have intracranial hemorrhage provides appropriate management so that the patients could be helped. Conclusion: Good collaboration between anesthesiologists, neurosurgeons, and pediatrics will increase the probability of successful management of critical bleeding without major sequelae.
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