Pub Date : 2024-01-29DOI: 10.20473/ijar.v6i12024.14-22
Irvan 1a, Doddy Tavianto, R. W. Sudjud
Introduction: The incidence of hyperglycemia in patients with heart disease undergoing cardiac surgery reaches 50% in patients without a history of Diabetes Mellitus. This condition of hyperglycemia can increase morbidity and mortality. Objective: This study aims to assess the effect of using the agent remifentanil intravenously 0.5-1 µg/kgBW bolus followed by maintenance at a dose of 0.05-0.1 µg/kgBW/minute intravenously compared to the use of fentanyl 3-10 µg/kgBW followed by a maintenance dose of 0.03-0.1 µg/kgBW/minute for increased blood sugar levels in patients undergoing cardiac surgery with the Cardiopulmonary Bypass (CPB) procedure. Materials and Methods: This study is an experimental study with a single-blind randomized controlled design. Patients will be divided into 2 groups consisting of 12 patients each, namely group R (remifentanil) received remifentanil, and group F (fentanyl) received fentanyl. Blood sugar levels will be checked before and after surgery. Results: The research has been conducted at Dr. Hasan Sadikin Hospital Bandung from February 2023 to May 2023. The average increase in blood sugar levels in the remifentanil group was 74 mg/dl, while in the fentanyl group, it was 90 mg/dl. The p-value given is 0.214. Statistical test results showed that the value of p> 0.05. Conclusion: This study concludes that there is no significant difference in the increase in blood sugar levels between the two groups (remifentanil and fentanyl). This can be caused by the use of opioid doses in the lower range and more complex surgical procedures in our research.
{"title":"Comparison of Intravenous Administration of Remifentanil with Fentanyl for Increased Blood Sugar Levels in Post Cardiac Surgery Patients","authors":"Irvan 1a, Doddy Tavianto, R. W. Sudjud","doi":"10.20473/ijar.v6i12024.14-22","DOIUrl":"https://doi.org/10.20473/ijar.v6i12024.14-22","url":null,"abstract":"Introduction: The incidence of hyperglycemia in patients with heart disease undergoing cardiac surgery reaches 50% in patients without a history of Diabetes Mellitus. This condition of hyperglycemia can increase morbidity and mortality. Objective: This study aims to assess the effect of using the agent remifentanil intravenously 0.5-1 µg/kgBW bolus followed by maintenance at a dose of 0.05-0.1 µg/kgBW/minute intravenously compared to the use of fentanyl 3-10 µg/kgBW followed by a maintenance dose of 0.03-0.1 µg/kgBW/minute for increased blood sugar levels in patients undergoing cardiac surgery with the Cardiopulmonary Bypass (CPB) procedure. Materials and Methods: This study is an experimental study with a single-blind randomized controlled design. Patients will be divided into 2 groups consisting of 12 patients each, namely group R (remifentanil) received remifentanil, and group F (fentanyl) received fentanyl. Blood sugar levels will be checked before and after surgery. Results: The research has been conducted at Dr. Hasan Sadikin Hospital Bandung from February 2023 to May 2023. The average increase in blood sugar levels in the remifentanil group was 74 mg/dl, while in the fentanyl group, it was 90 mg/dl. The p-value given is 0.214. Statistical test results showed that the value of p> 0.05. Conclusion: This study concludes that there is no significant difference in the increase in blood sugar levels between the two groups (remifentanil and fentanyl). This can be caused by the use of opioid doses in the lower range and more complex surgical procedures in our research.","PeriodicalId":117902,"journal":{"name":"Indonesian Journal of Anesthesiology and Reanimation","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140488664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-29DOI: 10.20473/ijar.v6i12024.58-72
Rifaldy Nabiel, Al Munawir, Jauhar Firdaus
Introduction: Several scoring systems were developed for early risk stratification in Upper Gastrointestinal Bleeding (UGIB) patients. AIMS65 score is a scoring system that only consists of five parameters, it might be used in daily clinical practice because of rapid and easy to calculate within 12 hours of admission. Objective: To evaluate the AIMS65 scoring system as a predictor of mortality, rebleeding events, need for endoscopic therapy, blood transfusion, and ICU admission for all causes of UGIB. Methods: We conducted a systematic review on PubMed, ScienceDirect, ProQuest, and Cochrane Library databases from the 2012 to 2022 publication period. We included either prospective or retrospective cohort studies that reported UGIB with all kinds of aetiologies who presented in the emergency department (ED), reported discriminative performance for each outcome, and reported the optimal cut-off of AIMS65. The primary measurement of discriminative performance for clinical outcomes includes mortality, rebleeding incidents, need for endoscopic therapy, blood transfusion, and ICU admission. Results: We identified 351 published studies, of which 20 were included in this study. Most of the studies reported discriminative performance for predicting mortality, which amounts to about 18 out of 20 studies. Rebleeding prediction was reported in 11 studies, need for endoscopic therapy in 5 studies, blood transfusion in 7 studies, and ICU admission in 2 studies. Most of the studies reported fair to excellent discriminative performance for predicting mortality, but in contrast for predicting rebleeding, the need for endoscopic therapy, blood transfusion, and ICU admission. Cut-off values≥ 2 are frequently reported to distinguish between high-risk and low-risk patients in mortality. Conclusion: AIMS65 can be applied to patients with UGIB in ED for predicting mortality, but not applicable for predicting rebleeding events, the need for endoscopic therapy, blood transfusion, and ICU admission. It enhances early decision-making and triage for UGIB patients.
{"title":"AIMS65 Scoring System for Predicting Clinical Outcomes Among Emergency Department Patients with Upper Gastrointestinal Bleeding","authors":"Rifaldy Nabiel, Al Munawir, Jauhar Firdaus","doi":"10.20473/ijar.v6i12024.58-72","DOIUrl":"https://doi.org/10.20473/ijar.v6i12024.58-72","url":null,"abstract":"Introduction: Several scoring systems were developed for early risk stratification in Upper Gastrointestinal Bleeding (UGIB) patients. AIMS65 score is a scoring system that only consists of five parameters, it might be used in daily clinical practice because of rapid and easy to calculate within 12 hours of admission. Objective: To evaluate the AIMS65 scoring system as a predictor of mortality, rebleeding events, need for endoscopic therapy, blood transfusion, and ICU admission for all causes of UGIB. Methods: We conducted a systematic review on PubMed, ScienceDirect, ProQuest, and Cochrane Library databases from the 2012 to 2022 publication period. We included either prospective or retrospective cohort studies that reported UGIB with all kinds of aetiologies who presented in the emergency department (ED), reported discriminative performance for each outcome, and reported the optimal cut-off of AIMS65. The primary measurement of discriminative performance for clinical outcomes includes mortality, rebleeding incidents, need for endoscopic therapy, blood transfusion, and ICU admission. Results: We identified 351 published studies, of which 20 were included in this study. Most of the studies reported discriminative performance for predicting mortality, which amounts to about 18 out of 20 studies. Rebleeding prediction was reported in 11 studies, need for endoscopic therapy in 5 studies, blood transfusion in 7 studies, and ICU admission in 2 studies. Most of the studies reported fair to excellent discriminative performance for predicting mortality, but in contrast for predicting rebleeding, the need for endoscopic therapy, blood transfusion, and ICU admission. Cut-off values≥ 2 are frequently reported to distinguish between high-risk and low-risk patients in mortality. Conclusion: AIMS65 can be applied to patients with UGIB in ED for predicting mortality, but not applicable for predicting rebleeding events, the need for endoscopic therapy, blood transfusion, and ICU admission. It enhances early decision-making and triage for UGIB patients.","PeriodicalId":117902,"journal":{"name":"Indonesian Journal of Anesthesiology and Reanimation","volume":"46 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140487353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-29DOI: 10.20473/ijar.v6i12024.32-41
Naomi Rahmasena, Mirza Koeshardiandi, Fajar Tri Mudianto
Introduction: Cluster headache is one of the neurovascular headaches characterized by severe recurrent unilateral pain distributed around the orbit and accompanied by autonomic symptoms such as lacrimation, conjunctival injection nasal congestion or rhinorrhea, edema of the eyelid, sweating, and miosis. The attack usually lasts for 15 to 180 minutes. The possible mechanism of cluster headache is through the trigeminal-autonomic reflex. Management of the cluster headache is divided into pharmacological therapy including abortive and prophylaxis, as well as interventional pain management like deep brain stimulation, occipital nerve stimulation, and radiofrequency of the sphenopalatine ganglion. Objective: This report aims to demonstrate the effectivity of pulsed radiofrequency sphenopalatine ganglion on cluster headaches secondary to meningioma. Case Report: A 47-year-old female consulted the pain clinic with a chief complaint of profound facial pain for a year. The patient also reported autonomic symptoms such as rhinorrhea and lacrimation. The patient was diagnosed with meningioma and already treated with conventional therapy such as gabapentine, carbamazepine, omeprazole, and mecobalamin. Due to the location of meningioma which causes the tumor inoperable. The patient complained of constant and worsening pain, therefore pulsed radiofrequency on sphenopalatine ganglion was chosen to treat the patient. The patient reported relief of pain ever since. Discussion: Among the consequences and benefits, pulsed radiofrequency is the choice of interventional pain management. Possibly the pain from the compression of the greater palatine nerve, intervention on the sphenopalatine will cause relief of the pain. Pulsed radiofrequency on sphenopalatine ganglion was reported successful in alleviating the pain of the patient. Conclusion: Pulsed radiofrequency of the sphenopalatine ganglion successfully alleviates the pain of the cluster headache due to meningioma. However, further study with a bigger population is recommended to see the efficacy of interventional pain management objectively.
{"title":"Pulsed Radiofrequency on Sphenopalatine Ganglion as the Interventional Pain Management in Cluster Headache Secondary to Sphenoid Meningioma","authors":"Naomi Rahmasena, Mirza Koeshardiandi, Fajar Tri Mudianto","doi":"10.20473/ijar.v6i12024.32-41","DOIUrl":"https://doi.org/10.20473/ijar.v6i12024.32-41","url":null,"abstract":"Introduction: Cluster headache is one of the neurovascular headaches characterized by severe recurrent unilateral pain distributed around the orbit and accompanied by autonomic symptoms such as lacrimation, conjunctival injection nasal congestion or rhinorrhea, edema of the eyelid, sweating, and miosis. The attack usually lasts for 15 to 180 minutes. The possible mechanism of cluster headache is through the trigeminal-autonomic reflex. Management of the cluster headache is divided into pharmacological therapy including abortive and prophylaxis, as well as interventional pain management like deep brain stimulation, occipital nerve stimulation, and radiofrequency of the sphenopalatine ganglion. Objective: This report aims to demonstrate the effectivity of pulsed radiofrequency sphenopalatine ganglion on cluster headaches secondary to meningioma. Case Report: A 47-year-old female consulted the pain clinic with a chief complaint of profound facial pain for a year. The patient also reported autonomic symptoms such as rhinorrhea and lacrimation. The patient was diagnosed with meningioma and already treated with conventional therapy such as gabapentine, carbamazepine, omeprazole, and mecobalamin. Due to the location of meningioma which causes the tumor inoperable. The patient complained of constant and worsening pain, therefore pulsed radiofrequency on sphenopalatine ganglion was chosen to treat the patient. The patient reported relief of pain ever since. Discussion: Among the consequences and benefits, pulsed radiofrequency is the choice of interventional pain management. Possibly the pain from the compression of the greater palatine nerve, intervention on the sphenopalatine will cause relief of the pain. Pulsed radiofrequency on sphenopalatine ganglion was reported successful in alleviating the pain of the patient. Conclusion: Pulsed radiofrequency of the sphenopalatine ganglion successfully alleviates the pain of the cluster headache due to meningioma. However, further study with a bigger population is recommended to see the efficacy of interventional pain management objectively.","PeriodicalId":117902,"journal":{"name":"Indonesian Journal of Anesthesiology and Reanimation","volume":"57 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140485947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-29DOI: 10.20473/ijar.v6i12024.23-31
Kübra Bektaş, Duygu Yücel, Fatih Uğur
Introduction: The most common effect of spinal anesthesia applied in cesarean section operations is hypotension. It is very important to prevent hypotension due to fetal bradycardia, acidosis, and maternal effects. Objective: This research was conducted to predict and prevent maternal hypotension in pregnant women undergoing elective cesarean section with spinal anesthesia by measuring heart rate variability parameters about hypotension. Materials and Methods: The study included pregnant women aged 18-45 with ASA 2 classification who underwent elective cesarean section with spinal anesthesia. Using the 'CorSense Heart Rate Variability Finger Sensor by Elite HRV' device and its smartphone application, 102 volunteer pregnant patients were monitored for 5 minutes in the recovery unit, and their data were recorded. After the administration of spinal anesthesia, patients who exhibited a decrease in systolic blood pressure of 20% or more from their baseline values received intravenous ephedrine in 10 mg bolus doses at each instance of low blood pressure measurements. Patients who received a total of 20 mg or more ephedrine doses or more as needed were designated as 'Group 1,' while patients who received less than 20 mg or no ephedrine were classified as 'Group 2.' Results: This study was completed with a total of 102 pregnant patients With 46 patients in Group 1 and 56 patients in Group 2, the relevant parameters that showed a statistically significant difference between patient groups were subjected to ROC analysis for predicting hypotension. It was determined that patients with high HF POWER and TOTAL POWER values had a greater need for vasopressors due to hypotension following spinal anesthesia (p<0.05). Conclusion: In the research, these values are believed to have the potential to predict hypotension in patients undergoing cesarean sections with spinal anesthesia.
{"title":"Investigation of Heart Rate Variability and The Requirement for Vasopressors Relationship Due to Hypotension in Patients Undergoing Caesarean Section with Spinal Anesthesia","authors":"Kübra Bektaş, Duygu Yücel, Fatih Uğur","doi":"10.20473/ijar.v6i12024.23-31","DOIUrl":"https://doi.org/10.20473/ijar.v6i12024.23-31","url":null,"abstract":"Introduction: The most common effect of spinal anesthesia applied in cesarean section operations is hypotension. It is very important to prevent hypotension due to fetal bradycardia, acidosis, and maternal effects. Objective: This research was conducted to predict and prevent maternal hypotension in pregnant women undergoing elective cesarean section with spinal anesthesia by measuring heart rate variability parameters about hypotension. Materials and Methods: The study included pregnant women aged 18-45 with ASA 2 classification who underwent elective cesarean section with spinal anesthesia. Using the 'CorSense Heart Rate Variability Finger Sensor by Elite HRV' device and its smartphone application, 102 volunteer pregnant patients were monitored for 5 minutes in the recovery unit, and their data were recorded. After the administration of spinal anesthesia, patients who exhibited a decrease in systolic blood pressure of 20% or more from their baseline values received intravenous ephedrine in 10 mg bolus doses at each instance of low blood pressure measurements. Patients who received a total of 20 mg or more ephedrine doses or more as needed were designated as 'Group 1,' while patients who received less than 20 mg or no ephedrine were classified as 'Group 2.' Results: This study was completed with a total of 102 pregnant patients With 46 patients in Group 1 and 56 patients in Group 2, the relevant parameters that showed a statistically significant difference between patient groups were subjected to ROC analysis for predicting hypotension. It was determined that patients with high HF POWER and TOTAL POWER values had a greater need for vasopressors due to hypotension following spinal anesthesia (p<0.05). Conclusion: In the research, these values are believed to have the potential to predict hypotension in patients undergoing cesarean sections with spinal anesthesia.","PeriodicalId":117902,"journal":{"name":"Indonesian Journal of Anesthesiology and Reanimation","volume":"24 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140490118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Team-based patient management in critical care demands a knowledgeable, skillful, and responsive doctor who collaborates well on teams. Medical education is responsible for producing competent graduates who meet the above requirements. However, the current medical curriculum in Indonesia tends to focus only on individual knowledge and appraisal. There was no standardized university-based group emergency training and examination with comprehensive emergency topics beyond cardiac and trauma cases. Objective: This study aimed to develop and evaluate a team-based emergency training program that enhances medical students' preparedness and teamwork skills in dealing with future emergencies in the workplace. Materials and Methods: We developed Acute Life Threatening Events Management (ALTEM), a three-day emergency training program consisting of pre-test, lectures, guided skill practice, group (case-based) simulation exam, and post-test. Group simulation occurred in a virtual hospital with high-fidelity mannequins, actual medical equipment (i.e., beds, monitors, drugs, tools, pads), two-way mirror rooms, and simulated patient family to resemble real hospital situations. The program was then evaluated by a modified Kirkpatrick evaluation model, which measures individual perception, satisfaction, understanding, and performance related to the program. Results: A total of 114 participants were involved in this study. Most subjects (>80%) had a good experience with the program. ALTEM training program significantly increased communication and teamwork (p <0.001) and decision-making towards critical patients (p <0.001) in the univariate analysis. Communication and teamwork remained related considerably in the multivariate analysis (aOR 7.866; p = 0.005). Conclusion: The ALTEM simulation program obtained a good response from the subjects and was a prospective program to improve medical students' competence and teamwork skills in emergencies.
导言：重症监护中以团队为基础的病人管理要求医生知识渊博、技术精湛、反应敏捷，并能在团队中良好协作。医学教育有责任培养出符合上述要求的合格毕业生。然而，印尼目前的医学课程往往只注重个人知识和评估。除了心脏和外伤病例之外，还没有以大学为基础的、包含综合急诊主题的标准化集体急诊培训和考试。研究目的本研究旨在开发和评估一个以团队为基础的急诊培训项目，以提高医学生在未来工作场所处理紧急情况时的准备能力和团队合作技能。材料与方法：我们开发了急性生命威胁事件管理（ALTEM），这是一个为期三天的急诊培训项目，包括前测、讲座、指导性技能练习、小组（基于病例）模拟考试和后测。小组模拟在虚拟医院内进行，医院内有高仿真人体模型、实际医疗设备（如病床、监护仪、药品、工具、护垫）、双向镜室和模拟病人家庭，以模拟真实的医院情况。然后，通过修改后的柯克帕特里克评估模型对该计划进行评估，该模型可测量与该计划相关的个人感知、满意度、理解力和绩效。结果：共有 114 人参与了这项研究。大多数受试者（>80%）对该项目体验良好。在单变量分析中，ALTEM 培训计划明显提高了沟通和团队合作能力（P <0.001），以及对危重病人的决策能力（P <0.001）。在多变量分析中，沟通和团队合作仍有很大关系（aOR 7.866; p = 0.005）。结论ALTEM模拟项目在受试者中反响良好，是提高医学生在紧急情况下的能力和团队合作技能的前瞻性项目。
{"title":"Developing an Effective Team-Based Emergency Training Program for Medical Students","authors":"Pinter Hartono, Bowo Adiyanto, Rifdhani Fakhrudin Nur, Cornelia Ancilla, Aulia Zuhria Rahma","doi":"10.20473/ijar.v6i12024.1-13","DOIUrl":"https://doi.org/10.20473/ijar.v6i12024.1-13","url":null,"abstract":"Introduction: Team-based patient management in critical care demands a knowledgeable, skillful, and responsive doctor who collaborates well on teams. Medical education is responsible for producing competent graduates who meet the above requirements. However, the current medical curriculum in Indonesia tends to focus only on individual knowledge and appraisal. There was no standardized university-based group emergency training and examination with comprehensive emergency topics beyond cardiac and trauma cases. Objective: This study aimed to develop and evaluate a team-based emergency training program that enhances medical students' preparedness and teamwork skills in dealing with future emergencies in the workplace. Materials and Methods: We developed Acute Life Threatening Events Management (ALTEM), a three-day emergency training program consisting of pre-test, lectures, guided skill practice, group (case-based) simulation exam, and post-test. Group simulation occurred in a virtual hospital with high-fidelity mannequins, actual medical equipment (i.e., beds, monitors, drugs, tools, pads), two-way mirror rooms, and simulated patient family to resemble real hospital situations. The program was then evaluated by a modified Kirkpatrick evaluation model, which measures individual perception, satisfaction, understanding, and performance related to the program. Results: A total of 114 participants were involved in this study. Most subjects (>80%) had a good experience with the program. ALTEM training program significantly increased communication and teamwork (p <0.001) and decision-making towards critical patients (p <0.001) in the univariate analysis. Communication and teamwork remained related considerably in the multivariate analysis (aOR 7.866; p = 0.005). Conclusion: The ALTEM simulation program obtained a good response from the subjects and was a prospective program to improve medical students' competence and teamwork skills in emergencies.","PeriodicalId":117902,"journal":{"name":"Indonesian Journal of Anesthesiology and Reanimation","volume":"59 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140486764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-29DOI: 10.20473/ijar.v6i12024.50-57
Muhammad Isra Rafidin Rayyan, Salman Sultan Ghiffari, Achmad Hariyanto, Achmad Wahib Wahju Winarso, Haris Darmawan, Ichlasul Mahdi Fardhani
Introduction: Heart failure is a condition caused by myocardial abnormalities that interfere with the fulfillment of the body's metabolism. It is one of the primary causes of high perioperative morbidity and mortality rates, and its management presents a challenge to anesthesiologists. Objective: To demonstrate combined spinal-epidural anesthesia with isobaric ropivacaine 0.375% for inguinal hernia repair surgery in a heart failure patient with an ejection fraction of 36%. Case Report: A 53-year-old man presented with a complaint of a lump on his left groin accompanied by pain with a visual analog scale (VAS) pain score of 3/10 three days before admission. The patient was also known to often complain of shortness of breath and chest palpitations when lying down at night and during strenuous activity. Based on the examination, the patient was then diagnosed with reducible left lateral inguinal hernia and heart failure with LVEF 36%. Subsequently, the patient was scheduled for elective herniotomy-hernioraphy surgery under low-dose combined spinal-epidural anesthesia. Spinal anesthesia was performed with isobaric ropivacaine 0.375% and fentanyl 25 μg in a total volume of 3.5 ml at the L3-L4 intervertebral space. Epidural anesthesia was performed with isobaric ropivacaine 0.375% and fentanyl 25 μg in a total volume of 8 ml at the L2-L3 intervertebral space. After 10 minutes, the sensory block reached the T6 level, but the motor block was only partial (Bromage 1). A continuous infusion of isobaric ropivacaine 0.1875% 1 ml/hour was administered through the epidural catheter to control postoperative pain. During surgery and hospitalization, the patient's hemodynamic condition remained stable. Conclusion: Combined spinal-epidural anesthesia with isobaric ropivacaine 0.375% can provide adequate anesthesia with relatively stable hemodynamics, thus making it safe for inguinal hernia repair surgery in heart failure patients with reduced ejection fraction.
{"title":"Combined Spinal-Epidural Anesthesia with Isobaric Ropivacaine 0.375% for Inguinal Hernia Surgery in a Heart Failure Patient with Ejection Fraction of 36%","authors":"Muhammad Isra Rafidin Rayyan, Salman Sultan Ghiffari, Achmad Hariyanto, Achmad Wahib Wahju Winarso, Haris Darmawan, Ichlasul Mahdi Fardhani","doi":"10.20473/ijar.v6i12024.50-57","DOIUrl":"https://doi.org/10.20473/ijar.v6i12024.50-57","url":null,"abstract":"Introduction: Heart failure is a condition caused by myocardial abnormalities that interfere with the fulfillment of the body's metabolism. It is one of the primary causes of high perioperative morbidity and mortality rates, and its management presents a challenge to anesthesiologists. Objective: To demonstrate combined spinal-epidural anesthesia with isobaric ropivacaine 0.375% for inguinal hernia repair surgery in a heart failure patient with an ejection fraction of 36%. Case Report: A 53-year-old man presented with a complaint of a lump on his left groin accompanied by pain with a visual analog scale (VAS) pain score of 3/10 three days before admission. The patient was also known to often complain of shortness of breath and chest palpitations when lying down at night and during strenuous activity. Based on the examination, the patient was then diagnosed with reducible left lateral inguinal hernia and heart failure with LVEF 36%. Subsequently, the patient was scheduled for elective herniotomy-hernioraphy surgery under low-dose combined spinal-epidural anesthesia. Spinal anesthesia was performed with isobaric ropivacaine 0.375% and fentanyl 25 μg in a total volume of 3.5 ml at the L3-L4 intervertebral space. Epidural anesthesia was performed with isobaric ropivacaine 0.375% and fentanyl 25 μg in a total volume of 8 ml at the L2-L3 intervertebral space. After 10 minutes, the sensory block reached the T6 level, but the motor block was only partial (Bromage 1). A continuous infusion of isobaric ropivacaine 0.1875% 1 ml/hour was administered through the epidural catheter to control postoperative pain. During surgery and hospitalization, the patient's hemodynamic condition remained stable. Conclusion: Combined spinal-epidural anesthesia with isobaric ropivacaine 0.375% can provide adequate anesthesia with relatively stable hemodynamics, thus making it safe for inguinal hernia repair surgery in heart failure patients with reduced ejection fraction.","PeriodicalId":117902,"journal":{"name":"Indonesian Journal of Anesthesiology and Reanimation","volume":"20 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140488560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-29DOI: 10.20473/ijar.v5i22023.88-95
Mirza Koeshardiandi, Pandhu Mahendra Bisama, Dian Muhammad Gibran
Introduction: Congestive heart failure (CHF) is a disease caused by abnormalities in the myocardium. This abnormality reduces the heart's ability to pump blood throughout the body. Anesthetic drugs have a major cardiovascular effect under general and regional anesthesia. Objective: This study aims to examine the effect of prilocaine as a subarachnoid block regional anesthetic drug in patients undergoing non-cardiac surgery with comorbid heart failure. Case Report: A 59-year-old man came complained of a lump in his left upper groin that had been present since a day before his admission to the hospital. The lump could not be inserted. The patient felt pain in the lump area with a visual analog score (VAS) of 7-8. His blood pressure was 138/84 mmHg, pulse rate was 104 times per minute, respiration rate was 22 times per minute, temperature was 36oC for axillary measurement, oxygen saturation was 92% based on room oxygen, and VAS was 7-8. The abdominal examination revealed a lump in the patient's left upper groin that could not be reinserted, hyperemic, and painful when pressed. With an EF Teich of 17.1%, the echocardiographic examination revealed that the dimensions of the patient’s heart chambers (RV and LV dilatation) and LV systolic function had decreased. Conclusion: Stable hemodynamics in non-cardiac surgery with a relatively short duration is the main choice for HF patients. Spinal anesthesia with a regimen of 2% prilocaine at a dose of 80 mg plus 0.1 mg morphine resulted in stable hemodynamics and low pain scores in patients with comorbid congestive heart failure undergoing non-cardiac surgery.
{"title":"Prilocaine 2% for Spinal Anesthesia in Incarcerated Inguinal Hernia Surgery with Congestive Heart Failure","authors":"Mirza Koeshardiandi, Pandhu Mahendra Bisama, Dian Muhammad Gibran","doi":"10.20473/ijar.v5i22023.88-95","DOIUrl":"https://doi.org/10.20473/ijar.v5i22023.88-95","url":null,"abstract":"Introduction: Congestive heart failure (CHF) is a disease caused by abnormalities in the myocardium. This abnormality reduces the heart's ability to pump blood throughout the body. Anesthetic drugs have a major cardiovascular effect under general and regional anesthesia. Objective: This study aims to examine the effect of prilocaine as a subarachnoid block regional anesthetic drug in patients undergoing non-cardiac surgery with comorbid heart failure. Case Report: A 59-year-old man came complained of a lump in his left upper groin that had been present since a day before his admission to the hospital. The lump could not be inserted. The patient felt pain in the lump area with a visual analog score (VAS) of 7-8. His blood pressure was 138/84 mmHg, pulse rate was 104 times per minute, respiration rate was 22 times per minute, temperature was 36oC for axillary measurement, oxygen saturation was 92% based on room oxygen, and VAS was 7-8. The abdominal examination revealed a lump in the patient's left upper groin that could not be reinserted, hyperemic, and painful when pressed. With an EF Teich of 17.1%, the echocardiographic examination revealed that the dimensions of the patient’s heart chambers (RV and LV dilatation) and LV systolic function had decreased. Conclusion: Stable hemodynamics in non-cardiac surgery with a relatively short duration is the main choice for HF patients. Spinal anesthesia with a regimen of 2% prilocaine at a dose of 80 mg plus 0.1 mg morphine resulted in stable hemodynamics and low pain scores in patients with comorbid congestive heart failure undergoing non-cardiac surgery.","PeriodicalId":117902,"journal":{"name":"Indonesian Journal of Anesthesiology and Reanimation","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122596143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-29DOI: 10.20473/ijar.v5i22023.112-121
Rifaldy Nabiel, Daniel Alexander Suseno, Yonas Hadisubroto, Taufiq Gemawan, Aurellia Nuraini Anindito Putri, Syadza Salsabila, Eprila Darma Sari
Introduction: Perioperative strategies to reduce postoperative pain are important for enhancing patient satisfaction. However, further research and trials has sparked ongoing debates of various strategies regarding efficacy and safety. Objective: This study aims to improve evidence-based strategies regarding the effect of paracervical anaesthetic blocks in patients undergoing laparoscopic hysterectomy. Materials and Method: A systematic literature search was conducted through PubMed, Google Scholar, and ScienceDirect for RCTs in laparoscopic hysterectomy patients administered paracervical blocks and those given placebos. The quantitative analysis of pooled relative risk and mean difference with a 95% confidence interval were performed using the Review Manager 5.4 software in the random-effects model or fixed-effects model forest plot. Results: Based on four RCTs included in the analysis, there were significant differences in overall postoperative pain scores assessed by VAS (Visual Analogue Scale) [MD = -0.82, 95%CI (-1.47 to -1.06), p = 0.01]. The subgroup analysis also showed significant differences in VAS pain scores at 30 min and 1 hour post-operation [MD = -2.13, 95% CI (-3.09 to -1.16), p = 0.0001] and [MD = -2.55, 95% CI (-4.29 to -0.81), p = 0.004]. However, there were insignificant results in adequate pain control [RR = 7.90, 95%CI (0.39 to 158.67), p = 0.18], length of hospital stay [MD = 0.01, 95%CI (-0.52 to 0.54), p = 0.96], additional analgesics requirement at 24 hours [RR = 0.88, 95%CI (0.55 to 1.39), p=0.58], and perioperative complications [RR = 0.90, 95%CI (0.56 to 1.47), p = 0.68].Conclusion: This meta-analysis provides evidence that the administration of paracervical block in patients undergoing laparoscopic hysterectomy is associated with a reduction of postoperative VAS pain score but not associated with the length of hospital stay, adequate pain control, additional analgesics requirement at 24 hours, and perioperative complications.
{"title":"Systematic Review and Meta-Analysis of Paracervical Blocks as A Perioperative Strategy in Reducing Postoperative Pain in Patients Undergoing Laparoscopic Hysterectomy","authors":"Rifaldy Nabiel, Daniel Alexander Suseno, Yonas Hadisubroto, Taufiq Gemawan, Aurellia Nuraini Anindito Putri, Syadza Salsabila, Eprila Darma Sari","doi":"10.20473/ijar.v5i22023.112-121","DOIUrl":"https://doi.org/10.20473/ijar.v5i22023.112-121","url":null,"abstract":"Introduction: Perioperative strategies to reduce postoperative pain are important for enhancing patient satisfaction. However, further research and trials has sparked ongoing debates of various strategies regarding efficacy and safety. Objective: This study aims to improve evidence-based strategies regarding the effect of paracervical anaesthetic blocks in patients undergoing laparoscopic hysterectomy. Materials and Method: A systematic literature search was conducted through PubMed, Google Scholar, and ScienceDirect for RCTs in laparoscopic hysterectomy patients administered paracervical blocks and those given placebos. The quantitative analysis of pooled relative risk and mean difference with a 95% confidence interval were performed using the Review Manager 5.4 software in the random-effects model or fixed-effects model forest plot. Results: Based on four RCTs included in the analysis, there were significant differences in overall postoperative pain scores assessed by VAS (Visual Analogue Scale) [MD = -0.82, 95%CI (-1.47 to -1.06), p = 0.01]. The subgroup analysis also showed significant differences in VAS pain scores at 30 min and 1 hour post-operation [MD = -2.13, 95% CI (-3.09 to -1.16), p = 0.0001] and [MD = -2.55, 95% CI (-4.29 to -0.81), p = 0.004]. However, there were insignificant results in adequate pain control [RR = 7.90, 95%CI (0.39 to 158.67), p = 0.18], length of hospital stay [MD = 0.01, 95%CI (-0.52 to 0.54), p = 0.96], additional analgesics requirement at 24 hours [RR = 0.88, 95%CI (0.55 to 1.39), p=0.58], and perioperative complications [RR = 0.90, 95%CI (0.56 to 1.47), p = 0.68].Conclusion: This meta-analysis provides evidence that the administration of paracervical block in patients undergoing laparoscopic hysterectomy is associated with a reduction of postoperative VAS pain score but not associated with the length of hospital stay, adequate pain control, additional analgesics requirement at 24 hours, and perioperative complications.","PeriodicalId":117902,"journal":{"name":"Indonesian Journal of Anesthesiology and Reanimation","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129257887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-29DOI: 10.20473/ijar.v5i22023.102-111
Z. Maritska, Nita Parisa, Mathius Karina, Marco Manza Putra, Noviyanti Eliska, Muhammad Irga, Maya Rina Santara Manurung, Andre Saputra
Introduction: Mitochondrial Disorders (1/4,000 patients) are rare and caused by dysfunctional mitochondria. Anesthetic consideration in patients with Mitochondrial Disorders involves careful preoperative and perioperative observations. Objective: To provide a brief insight into how general anesthetics interfere with mitochondrial energy formation pathways and help form precautions for anesthesiologists when managing patients with Mitochondrial Disorder. Review: Mitochondrial Disorder patients would experience various health problems, such as damaged cardiac functions, neurology systems, and musculoskeletal functions due to energy production disruptions by dysfunctional mitochondrial processes. Moreover, patients with Mitochondrial Disorders exhibit hyperreactivity to volatile anesthetics. Summary: No anesthetic strategies are found to be safe in patients with Mitochondrial Disorder yet. Therefore, anesthesiologists should remain alert when monitoring fluid choices and managing patient temperature with Mitochondrial Disorders.
{"title":"Anesthetic Considerations in Patients with Mitochondrial Disorders","authors":"Z. Maritska, Nita Parisa, Mathius Karina, Marco Manza Putra, Noviyanti Eliska, Muhammad Irga, Maya Rina Santara Manurung, Andre Saputra","doi":"10.20473/ijar.v5i22023.102-111","DOIUrl":"https://doi.org/10.20473/ijar.v5i22023.102-111","url":null,"abstract":"Introduction: Mitochondrial Disorders (1/4,000 patients) are rare and caused by dysfunctional mitochondria. Anesthetic consideration in patients with Mitochondrial Disorders involves careful preoperative and perioperative observations. Objective: To provide a brief insight into how general anesthetics interfere with mitochondrial energy formation pathways and help form precautions for anesthesiologists when managing patients with Mitochondrial Disorder. Review: Mitochondrial Disorder patients would experience various health problems, such as damaged cardiac functions, neurology systems, and musculoskeletal functions due to energy production disruptions by dysfunctional mitochondrial processes. Moreover, patients with Mitochondrial Disorders exhibit hyperreactivity to volatile anesthetics. Summary: No anesthetic strategies are found to be safe in patients with Mitochondrial Disorder yet. Therefore, anesthesiologists should remain alert when monitoring fluid choices and managing patient temperature with Mitochondrial Disorders.","PeriodicalId":117902,"journal":{"name":"Indonesian Journal of Anesthesiology and Reanimation","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124943332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-07-29DOI: 10.20473/ijar.v5i22023.96-101
Helen Yudi Irianto, A. Y. Jufan
Introduction: The Coronavirus disease 2019 (COVID-19) caused a global pandemic and many management challenges. Acute Respiratory Distress Syndrome (ARDS) is one of the most common pneumonia complications in COVID-19 cases. ARDS in COVID-19 have worse outcomes and increased risk of intensive care unit (ICU) admission. Objective: This case report aims to recognize and understand ARDS management in a severe COVID-19 case. Case Report: A 68-year-old man with diabetes mellitus and hypertension arrived at the Emergency Room (ER) after experiencing five days of fever, cough, diarrhea with frequency of four times a day, weakness, and a positive antigen result for COVID-19 at admission. Anosmia was absent. The patient had been vaccinated for COVID-19 twice. The main problem was his desaturation of 88%, blood pressure of 156/73 mmHg, heart rate of 80x/minute, and respiratory rate of 20x/minute. However, the patient was alert and admitted to the isolation ward. After 21 days of hospitalization, the patient's condition worsened. The patient developed ARDS and was referred to the COVID ICU for 25 days and 20 days to the non-COVID ICU, where he was intubated, and a tracheostomy was performed. After 45 days of admission to the ICU, the patient's condition improved. Discussion: COVID-19 patients with ARDS should be immediately intubated when conditions such as dyspnea, RR>30x/min, SpO2<92% (for patients with no comorbidities) or <95% (for patients with comorbidities), unconsciousness, or shock appears. Furthermore, other conditions, such as an HR> of 120x/min and a ROX index of <3.851, should be considered an indication for intubation. Conclusion: Timely intubation improves the outcome of COVID-19 patients with ARDS.
{"title":"Acute Respiratory Distress Syndrome (ARDS) Management Severe COVID-19","authors":"Helen Yudi Irianto, A. Y. Jufan","doi":"10.20473/ijar.v5i22023.96-101","DOIUrl":"https://doi.org/10.20473/ijar.v5i22023.96-101","url":null,"abstract":"Introduction: The Coronavirus disease 2019 (COVID-19) caused a global pandemic and many management challenges. Acute Respiratory Distress Syndrome (ARDS) is one of the most common pneumonia complications in COVID-19 cases. ARDS in COVID-19 have worse outcomes and increased risk of intensive care unit (ICU) admission. Objective: This case report aims to recognize and understand ARDS management in a severe COVID-19 case. Case Report: A 68-year-old man with diabetes mellitus and hypertension arrived at the Emergency Room (ER) after experiencing five days of fever, cough, diarrhea with frequency of four times a day, weakness, and a positive antigen result for COVID-19 at admission. Anosmia was absent. The patient had been vaccinated for COVID-19 twice. The main problem was his desaturation of 88%, blood pressure of 156/73 mmHg, heart rate of 80x/minute, and respiratory rate of 20x/minute. However, the patient was alert and admitted to the isolation ward. After 21 days of hospitalization, the patient's condition worsened. The patient developed ARDS and was referred to the COVID ICU for 25 days and 20 days to the non-COVID ICU, where he was intubated, and a tracheostomy was performed. After 45 days of admission to the ICU, the patient's condition improved. Discussion: COVID-19 patients with ARDS should be immediately intubated when conditions such as dyspnea, RR>30x/min, SpO2<92% (for patients with no comorbidities) or <95% (for patients with comorbidities), unconsciousness, or shock appears. Furthermore, other conditions, such as an HR> of 120x/min and a ROX index of <3.851, should be considered an indication for intubation. Conclusion: Timely intubation improves the outcome of COVID-19 patients with ARDS.","PeriodicalId":117902,"journal":{"name":"Indonesian Journal of Anesthesiology and Reanimation","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115707241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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