利用硅光电倍增管提高荧光成像的灵敏度和成像速度

Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN) Pub Date : 1900-01-01 DOI:10.1364/boda.2023.jtu4b.13

M. Giacomelli

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引用次数: 0

摘要

光电倍增管(pmt)是荧光信号高灵敏度检测的标准，但价格昂贵，易碎，QE有限，远红波长灵敏度较差。基于硅光电倍增管(SiPM)技术的新型探测器可以大大提高灵敏度和成像速率。综述了硅光电倍增管技术在高灵敏度、高速成像方面的优势和应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Improved Sensitivity and Imaging Speeds of Fluorescent Imaging Using Silicon Photomultipliers

Photomultiplier tubes (PMTs) are the standard for high sensitivity detection of fluorescence signals, but are costly, fragile, have limited QE and worse sensitivity at far-red wavelengths. Newer detectors based on silicon photomultiplier (SiPM) technology can greatly improve sensitivity and imaging rates. The advantages and utilization of silicon photomultiplier technology for high sensitivity and high-speed imaging are reviewed.

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Biophotonics Congress: Optics in the Life Sciences 2023 (OMA, NTM, BODA, OMP, BRAIN)

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