一种用于康复过程中肌电和乳酸测量的柔性印刷多传感平台的初步研究

Sarah Tonello, G. Giorgi, C. Narduzzi, Tiziano Fapanni, Edoardo Cantù, M. Serpelloni, E. Sardini, S. Carrara
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引用次数: 5

摘要

在康复和物理治疗领域,无论是医院还是家庭,对体育锻炼期间肌肉疲劳的实时测量都有很高的要求。除了从肌电图测量中提取的被广泛接受的特征外,最近人们对疲劳生化标记物的研究越来越感兴趣,以推动疲劳演变的更多信息。我们在这里提出了一种多传感的非侵入性方法,通过肌电图和乳酸传感来测量疲劳。通过新兴的气溶胶喷射打印技术,开发了一个印刷的不显眼的传感贴片作为第一个原型,即使在柔性基板上也能确保高重复性和稳定性。为了研究该贴片的行为,对两个印刷传感器进行了初步测量分析。肌电图电极的皮肤电极阻抗幅度和相位角与商业电极的趋势相当,表明有可能成功地从肌电图中提取平均和中位数频率,并检测到剧烈运动后它们的下降。乳酸静态测量的初步结果显示,在0-20 mM范围内,检测限为3.1±0.3 mM,线性度最高(R=0.9995),灵敏度为0.39µa /mM。此外,动态测试允许对传感器连续测量乳酸浓度变化的能力进行初步分析。总的来说,报告的测量方法代表了一个有希望的起点,即开发一种易于集成在任何可穿戴设备上的贴片,用于体育锻炼期间的非侵入性和完全定制的疲劳测量。
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Preliminary Study of a Flexible Printed Multi-Sensing Platform for Electromyography and Lactate Measuring during Rehabilitation
Real-time measure of muscular fatigue during physical exercise is highly demanded in fields as rehabilitation and physiotherapy, both hospital and home-based. In addition to the well-accepted features extracted from EMG measurements, an increasing interest has been recently addressed to the investigation of biochemical fatigue markers to drive additional information on fatigue evolution. We propose here a multi-sensing non-invasive approach to measure fatigue through EMG and lactate sensing. A printed unobtrusive sensing patch was developed as first prototype by means of the emerging Aerosol Jet Printing technique, ensuring high repeatability and stability even on a flexible substrate. To study the behavior of this patch, preliminary measurements were acquired to perform an analysis of both the printed sensors. EMG electrodes, with skin-electrodes impedance magnitude and phase angle with trends comparable to commercial electrodes, showed the possibility to successfully extract mean and median frequencies from EMG and to detect their decrease after intense exercise. Preliminary results on lactate static measure showed a limit of detection of 3.1±0.3 mM with the highest linearity (R=0.9995) and sensitivity (0.39 µA/mM) in the range 0-20 mM. Furthermore, dynamic tests permitted a preliminary analysis on the ability of the sensor to measure changes in the concentration of lactate continuously. Overall, reported measures represent a promising starting point to develop a patch easily integrable in any wearable for noninvasive and totally customized fatigue measure during physical exercise.
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