用于植入式生物医学设备的光学传感器和接口技术

J. Ohta
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引用次数: 0

摘要

近年来,基因工程与光学技术的结合使光测量和控制生物功能成为可能。荧光蛋白如GFP可作为特定分子的光学标签,光活性蛋白如ChR2可用于生物功能的光学操作。本文介绍了几种用于测量和控制自由运动啮齿动物大脑生物功能的植入式光学装置。展望了实现与大脑双向光通信的未来发展方向。
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Optical sensor and interface technologies for implantable biomedical devices
Recently, combination of genetic engineering and optical technology enables to measure and control biological functions with light. Fluorescent protein such as GFP can be used as an optical tag of a specific molecule, and photoactive protein such as ChR2 can be applied for optical manipulation of biological functions. This presentation introduces some kinds of implantable optical devices for measuring and controlling biological functions in the brain of a freely-moving rodent. Future direction is addressed for achieving bidirectional optical communication with brain.
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