恰加斯病心脏病患者心率变异性及风险分层分析

M. Vizcardo, J. Jiménez, F. Moleiro, A. Marcano, A. Octavio, A. Rodriguez
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引用次数: 5

摘要

据世界卫生组织称,感染克鲁兹三体病的人数被认为在1600万至1800万之间,这是恰加斯sila病的病因,1亿人中有1亿人面临感染风险。在1983年的一项研究中,纵向流行病学家每3年对该疾病患者进行一次评估,心脏病变:慢性Chagasic心肌炎(MCHC)从研究开始时的17%增加到15年后的49.4%。先前对Chagaspsila病患者心脏频率变异性的研究表明,HRV的频谱指数发生了变化。我们分析了62例心电图改变(CH2)患者、32例无心电图改变(CH1)且血清学结果阳性的chaspsila病患者和36例性别和年龄匹配的健康受试者(对照组)的24小时心率。我们发现了一个正交基,能够从昼夜节律剖面、对照和CH2中区分各组,并对CH1组进行分层。
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Analysis of the heart rate variability and stratification of the risk of cardiac patients with Chagas’ disease
According to the World wide Organization of the Health, the number of people infected with the Tri-panosoma Cruzi is considered between 16 and 18 million, causal agent of the Chagaspsila disease, and in 100 million the people exposed to the affectation risk. When concluding in 1983 a study longitudinal epidemiologist in patients with the disease evaluated every 3 years, the cardiac affectation: chronic Chagasic myocarditis (MCHC) increased from a 17% at the beginning of the study to a 49, 4% after 15 years. Previous studies of the variability of cardiac frequency in patients with the Chagaspsila disease, show alterations in the spectral indices of the HRV. We analyze the 24-hour heart rate by Holter recordings in 62 patients with ECG alterations (CH2), 32 patients without ECG alterations (CH1) who had positive serological findings for disease of Chagaspsila and 36 healthy subjects (control) matched for sex and age. We find a orthogonal base that is able to discriminate the groups from circadian profiles, control and CH2, and stratify the groups CH1.
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