用于生物医学文献中蛋白质-蛋白质相互作用文章分类的递归卷积神经网络

Sabenabanu Abdulkadhar, Gurusamy Murugesan, J. Natarajan
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引用次数: 4

摘要

文本分类(TC)是将文本分配给一个或多个类和预定义类别的任务。考虑到未标记文档中隐藏的大量信息,构建高精度文本分类器是生物医学领域的一项重要任务。由于特征空间大,传统的判别方法,如逻辑回归和具有n-gram和语义特征的支持向量机已被用于生物医学文本分类。在这项研究中,我们提出了基于递归卷积神经网络(RCNN)的蛋白质-蛋白质相互作用(PPI)文章自动分类技术。在RCNN模型中,我们利用循环结构来保留词嵌入特征中的上下文信息。配置最大池化层,从文本中提取重要的语义关键词。我们在两个基准PPI数据集BioCreative II和BioCreative III上评估了我们的方法。实验结果表明,基于RCNN的蛋白质-蛋白质相互作用分类方法比现有的分类方法性能更好。
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Recurrent convolution neural networks for classification of protein-protein interaction articles from biomedical literature
Text classification (TC) is a task that assigns a text to one or more classes and predefined categories. Constructing text classifiers with high accuracy is a vital task in biomedical field, given the wealth of information hidden in unlabelled documents. Because of large feature spaces, traditionally discriminative approaches, such as logistic regression and support vector machines with n-gram and semantic features have been utilizedfor biomedical text classification. In this study, we propose Recurrent Convolution Neural Networks (RCNN) based automated technique for classifying protein-protein interaction (PPI) articles. In RCNN model we utilized a recurrent structure to detain the contextual information from word embedding features. Max pooling layer was configured to extract important semantic keywords from the text. We evaluated our approach on two benchmark PPI datasets BioCreative II and BioCreative III. An experimental results show that RCNN based protein-protein interaction classification approach performs better than other state of the art approaches.
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