糖尿病引起的微量白蛋白尿——一项重要的综述

Bi Salim, Madhuri Devi N
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摘要

微量白蛋白尿是糖尿病肾并发症的标志和危险因素,在肾病的第三阶段,即早期肾病阶段开始在肾病的发病机制中发挥作用。微量白蛋白尿之后是明显的肾病和终末期肾脏疾病的不可逆肾损害。微量蛋白尿的早期检测对糖尿病患者的健康生存具有决定性的作用。尿白蛋白排泄率和白蛋白肌酐比值对定时尿样、清晨尿样或现场尿样均有有益的应用。印度草药医学将糖尿病描述为Prameha roga,其中主要发病机制优先于Moot-rasaya。微量白蛋白尿可以被描述为Prameha Janya Vrikka Roga。它的发生是由于白蛋白的异常运动(Vimarga Gamana);通过Rakta和Mootra Vaha Srotas(血液和尿液的通道)组成Raktadhatu(血液)的成分之一。Pramehaghna(抗糖尿病)、Mootra和Raktavaha Srothosodhana(清洁渠道)等药物可能对纠正微量白蛋白尿的病理有很好的价值,为糖尿病患者提供了改善生活的机会。
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DIABETES INDUCED MICROALBUMINURIA - A CRITICAL REVIEW
Microalbuminuria is a marker and a risk factor of diabetic renal complications commences its role in path-ogenesis of nephropathy at its third stage, the stage of incipient nephropathy. Microalbuminuria is followed by overt nephropathy and end- stage renal disease of irreversible renal damage. Early detection of microal-buminuria has a decisive role in the healthy survival of diabetics. Urine albumin excretion rate and albumin creatinine ratio on timed urine samples, early morning samples or spot urine are of beneficial use. Ayurve-da describes diabetes mellitus as Prameha roga in which the major pathogenesis takes precedence in Moot-rasaya. Microalbuminuria can be described as Prameha Janya Vrikka Roga. It occurs due to Sanga (ob-struction), Vimarga Gamana (abnormal movement) of albumin; one of the constituents of Raktadhatu (blood) through Rakta and Mootra Vaha Srotas (channels of blood and urine). Medicines which are Pramehaghna (anti-diabetic), Mootra and Raktavaha Srothosodhana (cleanse the channels) may be of good worth to rectify the pathology of microalbuminuria providing an improved life for diabetics.
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