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摘要

本文讨论了利用DNA非编码部分的微卫星调控基因表达的可能性。由于确定增加某些基因表达的机制是一项重要的农业任务,因此已经对“soybase”数据库中已知的SSRs进行了可能表现为增强子的分析。SSRs分析是在开放网络资源“ienchanger 2L”中进行的。结果表明,一些微卫星在理论上可以作为增强子,另一项研究表明,被鉴定为增强子的序列具有转录因子的特异性结合位点,这可以被认为是对所得结果的间接证实。所进行的研究有助于进一步寻找DNA调控位点,并促进对DNA非编码部分意义的理解。
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On the possibility of regulatory influence of SSRs in Glycine Max (L.) Merr
This paper discusses the possibility of regulating gene expression by microsatellites of the non-coding part of DNA. The analysis of known SSRs from the "soybase" database for possible manifestation as enhancers has been carried out, since the determination of mechanisms for increasing the expression of certain genes is an important agricultural task. The SSRs analysis was carried out in the open web resource "iEnchancer 2L". As a result, it was revealed that some microsatellites are theoretically capable of being enhancers, an additional study showed that the sequences identified as enhancers have specific binding sites for transcription factors, which can be considered an indirect confirmation of the results obtained. The conducted studies can help to further work on the search for regulatory DNA sites, as well as advance in understanding the significance of the non-coding part of DNA.
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