c反应蛋白在COVID-19轻度感染患者中的预后指标

S. Alabd, A. Yameny
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引用次数: 3

摘要

背景:寻找一种简单有效的预后指标是对潜在危重患者进行高预警和治疗,降低病死率的关键,血清CRP是一种简单有效的预测潜在危重患者的指标,血清CRP具有预测covid - 19的价值。患者和方法:本研究纳入328例确诊COVID-19感染的门诊患者,这些研究对象随机选择,不考虑年龄组和性别,试验程序按照说明书,使用西班牙巴塞罗那Cromatest Linear chemicals S.L.U.试剂。结果:女性(n=192, 58.5%)多于男性(n=136, 41.5%)。本研究发现296例患者CRP水平较高(90.2%),敏感性为90.2%,分为两组,第一组CRP水平为5-100(56.1%),第二组CRP水平大于100 (34.1%),CRP水平高是门诊患者(门诊和居家观察患者)诊断或预后的重要生物标志物,p值为p < 0.00001,小于0.05。结论:CRP水平与肺部病变轻度COVID-19感染呈正相关,敏感性为90.2%。CRP水平可以反映疾病的严重程度,应作为疾病监测的关键指标。
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C-Reactive Protein as a Prognostic Indicator in COVID-19 mild infection Patients
Background: the identification of a simple and effective prognosticator is crucial for high lightening and treating the potentially critical patients, to reduce the mortality rate, Serum CRP is a simple and effective prognosticator which casts light on potentially critical patients, Serum CRP has a predictive value of COVID19. Patients and methods: This study included 328 out-hospitalized patients with confirmed COVID-19 infection, these study subjects were randomly selected irrespective of the age group and both genders were included, Assay procedure as manufactory instructions and Reagents of Cromatest Linear chemicals S.L.U. Barcelona Spain turbidimetric method is used. Results: Female gender was more frequent (n=192, 58.5%) than Male gender (n=136, 41.5%). This study reveals a high level of CRP in 296 patients (90.2%) with a sensitivity of 90.2%, which is divided into two groups the first have CRP levels 5-100 (56.1%) and the second group has CRP levels more than 100 (34.1%), the high-level CRP was a significant biomarker for COVID-19 diagnosis or prognosis in out-hospitalized patients (Outpatients and patients under home observation), with a p-value is p is < .00001which less than 0.05. Conclusion: CRP levels were positively correlated with mild COVID-19 infection of lung lesions with a sensitivity of 90.2%. CRP levels could reflect disease severity and should be used as a key indicator for disease monitoring.
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