麻醉深度:测量还是猜测?

Richard Landers, P. Wen, S. Pather
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引用次数: 5

摘要

本文对麻醉深度(DoA)监测问题进行了全面的文献综述。本文首先调查了目前临床实践,然后简要介绍了DoA监测仪,最后对目前DoA评估实践的可靠性和准确性进行了分析和讨论。在本研究中,我们发现麻醉剂抑制的大多数反应不是中枢神经系统的,而是来自周围神经系统的反应。在不同的治疗范围内,药物组合所产生的反应显示出药物浓度的相当大的变化,这些变化构成了对特定刺激的充分麻醉。我们建议使用神经网络来捕捉麻醉师的决策过程,因为神经网络擅长在非线性、非平稳信号中发现模式。
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Depth of Anaesthesia: Measuring or guessing?
This paper is a comprehensive literature review on the Depth of Anaesthesia (DoA) monitoring problem. We first investigate the current clinical practice, then briefly introduce the DoA monitors, finally we analyse and discuss the reliability and accuracy of current DoA assessment practice. In this study we find that most of the responses suppressed by anaestheic agents are not of the central nervous system (CNS) but are responses from the peripheral nervous systems (PNS). The responses generated for drug combinations across the therapeutic ranges show considerable variations in drug concentrations that constitute adequate anaesthesia for a particular stimulus. We propose to capture the decision process of anaesthetist using neural networks as neural networks are good at finding patterns in non linear, non stationary signals.
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