抗癌药物顺铂在纳米管中的包封

T. Hilder, J.M. Hill
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引用次数: 24

摘要

纳米技术的一个重要应用是药物递送,特别是使用纳米管靶向递送药物。正确理解药物分子在纳米管中的包封行为对于纳米级药物递送载体的开发至关重要。此外,还有许多其他材料可以形成单壁纳米管,如碳、碳化硼、氮化硼和硅,了解它们的优缺点也很重要。本文综述了近年来氮化硼、碳化硼和硅纳米管作为药物递送载体的研究进展,并将它们的包封行为与前人在碳纳米管方面的研究成果进行了比较。
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Encapsulation of the anticancer drug cisplatin into nanotubes
One important application of nanotechnology is that of drug delivery, and in particular the targeted delivery of drugs using nanotubes. A proper understanding of the encapsulation behavior of drug molecules into nanotubes is vital for the development of nanoscale drug delivery vehicles. Furthermore, there are many other materials which may form single-walled nanotubes, such as carbon, boron carbide, boron nitride and silicon, and it is also important to understand their advantages and disadvantages. This paper presents a synopsis of the recent work in which boron nitride, boron carbide and silicon nanotubes are examined as drug delivery vehicles, and their encapsulation behavior is compared to previous work of the authors on carbon nanotubes.
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