服用拟交感神经药物后的中枢性浆液性脉络膜视网膜病变:尼日利亚阿布贾1例报告

Nurat Adeleye, Chidinma Ohuabunwa, A. Okudo, Aisha Abubakar
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摘要

中枢性浆液性脉络膜视网膜病变(CSCR)主要表现为视网膜下积液,常导致视力扭曲。本病例报告描述了一例CSCR患者。一名34岁男子于2019年10月到眼科诊所就诊,主诉视力模糊和变形,未经治疗5个月后病情恶化。患者曾因复发性感冒服用含苯肾上腺素、伪麻黄碱和麻黄碱的混合物3年。检查视力为RE 6/9 LE 6/7.5,左侧黄斑可见圆形浆液性脱离,视网膜下有乳白色沉积物。光学相干断层扫描显示视网膜厚度360.5±94.7µm,黄斑水肿。患者接受玻璃体内注射雷尼单抗和停止使用拟交感神经药物治疗,一个月内视力略有改善。随访2年无复发。慢性摄入拟交感神经制剂与发生CSCR的风险之间可能存在关联。
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Central serous chorioretinopathy following ingestion of sympathomimetics: A case report from Abuja, Nigeria
Central serous chorioretinopathy (CSCR) manifests mainly with the buildup of fluids beneath the retina often leading to distorted vision. This case report describes a patient with CSCR. A 34-year-old man presented to the eye clinic in October 2019 with complaints of blurry vision and metamorphopsia, which got worsened after 5 months of no treatment. The patient had a history of intake of a mixture containing phenylephrine, pseudoephedrine, and ephedrine over a period of 3 years for recurrent cold. Upon examination, his visual acuity was RE 6/9 LE 6/7.5 and his left macula was seen having a round serous detachment with creamy-white subretinal deposits. Optical coherence tomography revealed a retinal thickness of 360.5 ± 94.7 µm and macular edema. He was treated with intravitreal ranibizumab and cessation of sympathomimetic drugs with a modest visual improvement achieved within a month. There has been no reoccurrence over the 2-year period he was followed up. There could be an association between chronic ingestion of sympathomimetics and the risk of developing CSCR.
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