[测定吞噬细胞中髓过氧化物酶活性的分光光度法]。

Laboratornoe delo Pub Date : 1991-01-01
M Z Saidov, B V Pinegin
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引用次数: 0

摘要

一种分光光度法已开发用于测量骨髓过氧化物酶活性的吞噬细胞,并规定了测量条件。单核细胞对髓过氧化物酶活性的贡献被发现可以忽略不计,中性粒细胞和嗜酸性粒细胞在这里起主要作用。发现髓过氧化物酶活性在慢性肉芽肿病、无球蛋白血症患者中降低,在高ige -综合征患者中升高;该参数在共济失调毛细血管扩张和慢性皮肤粘膜念珠菌病中没有变化。
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[A spectrophotometric method of determining the myeloperoxidase activity in phagocytic cells].

A spectrophotometric method has been developed for measurements of myeloperoxidase activity in phagocytes, and conditions of measurements specified. Contribution of mononuclear cells to myeloperoxidase activity was found negligible, the major role here was played by neutrophils and eosinophils. Myeloperoxidase activity was found reduced in the patients with chronic granulomatous disease, agammaglobulinemia, and elevated in hyper-IgE-syndrome; this parameter was unchanged in ataxia telangiectasia and chronic dermatomucosal candidiasis.

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