IPS细胞源性心肌细胞收缩负荷依赖性测定

2018 IEEE Micro Electro Mechanical Systems (MEMS) Pub Date : 2018-04-24 DOI:10.1109/MEMSYS.2018.8346500

Kenei Matsudaira, Hidetoshi Takahashi, K. H. Shoji, Thanh-Vinh Nguyen, T. Tsukagoshi, I. Shimoyama

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引用次数: 1

摘要

在本文中，我们提出了一种方法来评估抽搐力和iPS细胞来源的心肌细胞(iPSC-CMs)的静态拉伸刺激之间的关系(力-长度关系)。该方法实现了iPSC-CMs在培养条件下静态拉伸的抽动力测量。因此，我们测量了几十个μΝ的抽动力，并观察了随着静态拉伸的增加，抽动力的变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Load dependency measurement of IPS cell-derived cardiomyocytes' contraction

In this paper, we propose a method to evaluate relationships between twitch forces and static stretch stimuli of iPS cell-derived cardiomyocytes (iPSC-CMs) (force-length relation). The method realized the twitch force measurement of iPSC-CMs statically stretched under the culturing condition. As a result, twitch forces of a few tens of μΝ were measured, and the variation of twitch forces was observed as the static stretch was increased.

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2018 IEEE Micro Electro Mechanical Systems (MEMS)

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