Primary Malignant Melanoma of The Small Intestine

Primary small intestinal melanoma is a rare malignant neoplasm, for which scarce literature offers limited evidence for optimal management. We present a case of a 60-year-old female with primary melanoma of ileum. She presented with left sided abdominal pain, decreased appetite, and history of diarrhoea for 15 days. She developed absolute constipation during her preoperative investigations, in which CT scan revealed ileoileal intussusception. She underwent laparotomy for the resection of intussuscepted bowel segment, which revealed a greyish brown mass attached to bowel, later confirmed by histopathology as melanoma. Postoperative detailed clinical investigation revealed no primary cutaneous, hepatic, pulmonary, ocular, or cranial melanotic lesion. Hence, the lesion was classified as primary small bowel melanoma. She was referred to oncologist who started her on adjuvant chemotherapy. The patient expired of cardiopulmonary arrest three months after her diagnosis due to post Chemotherapy side effects.