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Smokeless Tobacco A Deadly Addiction 无烟烟草是致命的上瘾
Pub Date : 2022-12-30 DOI: 10.46663/ajsmu.v8i2.82
Wajiha Zia, M. Kashif
Although there are several tobacco products available, smokeless tobacco is the most commonly used1. SLT is being used more frequently, which can be attributable to its low price and straightforward accessibility in every other store around. SLTs are oral tobacco products that are non-combustible. It can also be breathed through the nose; however, it is typically inserted under the tongue or in the space between the cheeks and gums. SLTs come in a variety of forms, including as dipping tobacco, snuff, betel-quid, mawa, naswar, and gutka.
虽然有几种烟草产品可供选择,但无烟烟草是最常用的。SLT的使用频率越来越高,这可以归因于它的低价格和在周围所有其他商店都可以直接获得。slt是不可燃的口服烟草制品。它也可以通过鼻子呼吸;然而,它通常被插入舌头下或脸颊和牙龈之间的空间。slt有多种形式,包括浸渍烟草、鼻烟、槟榔、mawa、naswar和gutka。
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引用次数: 0
The Correlation of Peak Expiratory Flow Rate and Hand Dynamometry in Chronic Obstructive Pulmonary Disease Patients A Case Control study 慢性阻塞性肺疾病患者呼气峰流速与手部动力学的相关性:病例对照研究
Pub Date : 2022-12-30 DOI: 10.46663/ajsmu.v8i2.69-73
Erum Afaq, Muhammed Nisar, Muhammad Irfan, Syed Hafeez-ul- Hassan, Talha Ahmed
Objectives: To determine the correlation of peak expiratory flow rate and hand dynamometry in patients with chronic obstructive pulmonary disease and to find out the differences between hand grip in cases and control group Methodology: This study was carried out in the Department of Physiology and Department of Chest Medicine, Liaquat National Hospital and Medical College between July 1st 2019 and June 30th 2020 after the approval of the research and ethical committee of the same hospital. We used purposive sampling technique. Total 100 consenting individuals were recruited that were equally divided into control group and chronic obstructive pulmonary disease group. Anthropometric measurements alongwith peak expiratory flow rate and hand dynamometry values were measured. Results: We found significant difference in hand grip strength and peak expiratory flow rate between the case and control groups, chronic obstructive pulmonary disease patients have decreased peak expiratory flow rate and handgrip strength. Weak correlation exists between peak expiratory flow rate and hand grip strength with significant p value. No relationship was found between waist hip ratio and hand grip. Also, body mass index showed a weak negative but statistically significant correlation with hand grip strength. Conclusion: In chronic obstructive pulmonary disease patients, hand grip strength is decreased and determining hand grip strength may ensures quick assessment of quality of life.
目的:确定慢性阻塞性肺疾病患者呼气峰流速与手部动力学的相关性,并了解病例与对照组的握力差异。方法学:本研究于2019年7月1日至2020年6月30日在利亚奎特国立医院医学院生理科和胸内科进行,经该医院研究和伦理委员会批准。我们采用了有目的的抽样技术。总共招募了100名同意的个体,将其平均分为对照组和慢性阻塞性肺疾病组。测量了人体测量值以及呼气峰值流速和手动力测量值。结果:与对照组相比,慢性阻塞性肺疾病患者的握力和呼气峰流速有显著性差异,慢性阻塞性肺疾病患者的呼气峰流速和握力明显降低。呼气流量峰值与握力呈弱相关,p值显著。腰臀比与握力之间没有关系。身体质量指数与握力呈弱负相关,但有统计学意义。结论:慢性阻塞性肺疾病患者手部握力下降,确定手部握力可确保快速评估生活质量。
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引用次数: 0
Awareness of HPV Infection and its Relationship to Cervical Cancer in Medical Students of Karachi, Pakistan A Cross Sectional Study 巴基斯坦卡拉奇医科学生HPV感染意识及其与宫颈癌关系的横断面研究
Pub Date : 2022-12-30 DOI: 10.46663/ajsmu.v8i2.74-79
K. Kumari, A. Lari, A. Shahid, A. Farooqui, K. Abbas, F. Bashir
Objective: To assess the level of awareness among medical students about HPV, its vaccines and its relation to cervical cancer Methodology: This is a cross-sectional, multicenter study conducted at Creek General Hospital, Karachi from March 2020 to November 2021 after IRB approval from United Medical and Dental College. Data was collected from undergraduate MBBS students via an online questionnaire. Results: Total participants in the study were 219. Age range was between 18 and 26 years. A majority (82%) of medical students were aware of the causal relationship between HPV and cervical carcinoma. Only 53% of students had the knowledge for the need for regular pap smear. Students confessed about lack of knowledge regarding HPV and its preventive measures with 82% of students admitting to having gaps in their knowledge. Conclusion: The study brings us to the conclusion that the current medical curriculum is not fortified and hence the medical students are unaware about the diagnostic and preventive strategies of cervical cancer which is a good gap in their clinical career.
目的:评估医学生对HPV、其疫苗及其与宫颈癌的关系的认识水平。方法:这是一项横断面、多中心研究,经联合医学和牙科学院的IRB批准,于2020年3月至2021年11月在卡拉奇的Creek总医院进行。数据通过在线问卷从MBBS本科生中收集。结果:本组共219人。年龄在18至26岁之间。大多数(82%)医学生知道HPV与宫颈癌之间的因果关系。只有53%的学生了解定期做子宫颈抹片检查的必要性。学生承认缺乏关于HPV及其预防措施的知识,82%的学生承认他们的知识存在差距。结论:当前的医学课程设置不够完善,导致医学生对宫颈癌的诊断和预防策略不了解,这是医学生在临床生涯中存在的一个很大的差距。
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引用次数: 0
Stem Cell Role in Regenerative Dental Medicine 干细胞在再生牙科医学中的作用
Pub Date : 2022-12-30 DOI: 10.46663/ajsmu.v8i2.45-46
Robia Ghafoor
Regeneration therapies have widely permeated advanced research that aims to reproduce and repair a lost or damaged organ or tissue in order to restore the function and architecture as close to its original state as possible. Tissue engineering refers to the process of regeneration using techniques such as scaffold based cell cultures, stem cell therapy, and biomolecular signaling.
再生疗法已经广泛渗透到先进的研究中,其目的是复制和修复丢失或受损的器官或组织,以恢复功能和结构,尽可能接近其原始状态。组织工程是指利用支架细胞培养、干细胞治疗和生物分子信号传导等技术进行再生的过程。
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引用次数: 0
Contraceptive Usage and Social Barriers During The Covid-19 Pandemic Covid-19大流行期间的避孕使用和社会障碍
Pub Date : 2022-12-30 DOI: 10.46663/ajsmu.v8i2.64-68
R. Mustafa, Sagheera Anjum Munaver, Anjum Munaver
Objective: To determine the frequency of contraceptive usage, the social barriers affecting their use, and the frequency of unplanned pregnancies during the COVID-19 pandemic Methodology: This is a prospective cross-sectional study carried out at the Department of Obstetrics and Gynaecology, Fazaia Ruth Pfau Medical College & PAF Hospitals from July 2020 to September 2020. All women of reproductive age attending the outpatient department were consecutively included. A pre-structured questionnaire was used for the purpose of collection of data. We obtained information regarding the use of contraception before and during the COVID-19 pandemic and the contraception methods used by these women. Furthermore, reasons for discontinuing contraception amongst those women who were using it earlier. The occurrence of pregnancy during pandemic was also noted. Results: Of the 350 women, 306 (87.4%) women practiced contraception before and 288 (82.3%) practiced it during the lockdown. Of 306 women practicing contraception before the lockdown, 265 (86.6%) continued practicing during the lockdown as well. Condom 145 (50.3%) and withdrawal method 116 (40.3%) were the most used methods amongst the 288 women practicing contraception during the lockdown. The noticeable increase in the number of those using withdrawal method was due to the lack of consultation following the fear of getting COVID (17 women, 41.5%) and no access to the clinic (14 women, 34.1%). These were the most common reasons for not using contraception, amongst the 41 women practicing contraception before the pandemic. Pregnancies were reported by 93 (26.6%) women out of whom 75 (80.6%) reported these to have been unplanned. Conclusion: The COVID pandemic has largely affected the utilization of contraceptives among women who were already practicing different contraceptive methods. Moreover, unplanned pregnancies are increasingly reported by women.
目的:了解2019冠状病毒病大流行期间避孕药具使用频率、影响其使用的社会障碍以及意外怀孕频率。方法学:这是一项前瞻性横断面研究,于2020年7月至2020年9月在Fazaia Ruth Pfau医学院和PAF医院妇产科进行。连续纳入门诊就诊的所有育龄妇女。为了收集数据,我们使用了一份预先结构化的问卷。我们获得了有关COVID-19大流行之前和期间使用避孕措施以及这些妇女使用的避孕方法的信息。此外,先前使用避孕措施的妇女停止避孕的原因。还注意到在大流行期间怀孕的情况。结果:在350名女性中,306名(87.4%)女性在封锁前采取了避孕措施,288名(82.3%)女性在封锁期间采取了避孕措施。在封锁前采取避孕措施的306名妇女中,265名(86.6%)在封锁期间继续采取避孕措施。288名封锁期间采取避孕措施的女性中,使用最多的方法是避孕套145(50.3%)和退出法116(40.3%)。由于担心感染新冠病毒而没有进行咨询(17名,41.5%)和无法前往诊所(14名,34.1%),使用戒断方法的人数明显增加。在大流行前采取避孕措施的41名妇女中,这些是不采取避孕措施的最常见原因。93名(26.6%)妇女报告怀孕,其中75名(80.6%)报告怀孕是计划外的。结论:COVID大流行在很大程度上影响了已经采用不同避孕方法的妇女对避孕药具的使用。此外,越来越多的妇女报告意外怀孕。
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引用次数: 0
Effects of Dynamization on Delayed Union of Tibial Shaft Fractures After Reamed Intramedullary Interlocked Nailing 动力对扩髓交锁髓内钉后胫干骨折延迟愈合的影响
Pub Date : 2022-12-30 DOI: 10.46663/ajsmu.v8i2.59-63
Pervez Ali, Mian Sajjad, M. Hussain, Fahad Jatoi, Ejaz Matlo, Riaz Khoso
Objective: To determine the efficacy of dynamization in delayed union of tibia diaphyseal fractures Methodology: A descriptive cross sectional study was done at the Department of Orthopaedic Surgery, Jinnah Postgraduate Medical Center, Karachi, Pakistan, from July 2020 to April 2021. A total of 97 consenting patients who suffered from delayed union following intramedullary interlocking nailing were included in the study. Dynamization involved removal of proximal or distal locking screws in statically locked intramedullary nail. Patients were followed up for six months to check for delayed bone union. All the collected data were entered into a pro forma and used electronically for research purpose. Results: Over all union was achieved in 72 (74.2%) cases after dynamization. The mean age of our study population was 39.42+13.79 years. Advanced age, smoking, fresh or old fracture, the time of initial intramedullary nailing, and diabetes were associated with decreased efficacy of dynamization, with p-value <0.001, 0.033, 0.007, and <0.001 respectively. While no significant association was found between gender, BMI, hypertension, and union (p-value >0.05). Conclusion: The findings of this study support the idea that dynamization can be an effective method to promote healing in tibia diaphyseal fractures for delayed union. More randomized comparative clinical trials are necessary to evaluate the effectiveness of dynamization.
目的:探讨动力化治疗胫骨骨干骨折延迟愈合的疗效。方法:于2020年7月至2021年4月在巴基斯坦卡拉奇真纳研究生医学中心骨科进行描述性横断面研究。共有97名患者同意在髓内交锁钉治疗后延迟愈合被纳入研究。动力化包括移除静锁定髓内钉的近端或远端锁定螺钉。随访6个月,检查骨愈合是否延迟。所有收集到的数据都被输入到一个表格中,并以电子方式用于研究目的。结果:术后72例(74.2%)患者愈合良好。我们研究人群的平均年龄为39.42+13.79岁。高龄、吸烟、新或旧骨折、首次髓内钉时间、糖尿病与动力化效果降低相关,p值均为0.05)。结论:本研究结果支持动力化是促进胫骨骨干骨折延迟愈合的有效方法。需要更多的随机对照临床试验来评估动力化的有效性。
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引用次数: 0
COVID-19 Inside Out In-hospital Outcomes at a Public Sector Tertiary Care Hospital in Karachi 卡拉奇一家公立三级医疗医院的COVID-19住院结果
Pub Date : 2022-12-30 DOI: 10.46663/ajsmu.v8i2.54-58
Saima Akhter, Nausheen Saifullah, B. Hassan, S. Jafri, Naseem Ahmed
Objective: To present in-hospital COVID-19 mortality and the associated factors at a public sector tertiary care hospital in Karachi Methodology: The current prospective, observational study was conducted at Jinnah Postgraduate Medical Center, Karachi, Pakistan from June 1 to August 30, 2021 with the approval of the hospital ethics committee. Data was collected prospectively from patients’ medical record files. COVID-19 infection positive cases were diagnosed according to the guidelines of the WHO on laboratory investigation of real time polymerase chain reaction tests on a nasopharyngeal or oropharyngeal swab. Result: Total 143 patients were enrolled in the study with median (IQR) age of 58 (48–69). The majority of the patients were males (n=96, 67.13%) and had moderate to severe disease (n=128, 89.51%). During their hospital stay, patients developed the following complications; pneumonia (n=99, 69.23%), ARDS (n=19, 13.28%), sepsis (n=11, 7.69%), septic shock (n=5, 3.49%) and pedal edema (n=2, 1.39%). As many as 104 (72.72%), 69 (48.25%), and 42(29.37%) patients required pharmatherapy, non-invasive ventilation, and mechanical ventilation respectively. While 54 (37.76%) patients died during their hospital stay. On multivariable model, pneumonia, use of non-invasive ventilation, and mechanical ventilation, were identified as independent predictors of mortality. Conclusion: Most of the patients in our study had moderate to severe disease. Therefore, the study indicates that timely presentation to the hospital is of great importance to avoid adverse events which are significantly associated with mortality.
目的:了解卡拉奇一家公立三级医疗医院的COVID-19住院死亡率及其相关因素。方法学:本前瞻性观察性研究于2021年6月1日至8月30日在巴基斯坦卡拉奇真纳研究生医学中心进行,并获得医院伦理委员会的批准。前瞻性地从患者病历文件中收集数据。根据世界卫生组织《鼻咽或口咽拭子实时聚合酶链反应实验室调查指南》诊断新冠肺炎感染阳性病例。结果:共有143例患者入组,中位(IQR)年龄为58(48-69)。患者以男性为主(n=96, 67.13%),以中重度为主(n=128, 89.51%)。在住院期间,患者出现以下并发症:肺炎(n=99, 69.23%)、ARDS (n=19, 13.28%)、脓毒症(n=11, 7.69%)、感染性休克(n=5, 3.49%)、足部水肿(n=2, 1.39%)。需要药物治疗、无创通气和机械通气的患者分别为104例(72.72%)、69例(48.25%)和42例(29.37%)。54例(37.76%)患者在住院期间死亡。在多变量模型中,肺炎、使用无创通气和机械通气被确定为死亡率的独立预测因素。结论:本组患者多为中重度。因此,研究表明,及时到医院就诊对于避免与死亡率显著相关的不良事件至关重要。
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引用次数: 0
Surgical Repair of Nasal Vestibular Stenosis A Case Report 鼻前庭狭窄的外科修复1例
Pub Date : 2022-12-30 DOI: 10.46663/ajsmu.v8i2.80-81
Beenish Nisar Ahmed, Muhammad Yasir Khan
Vestibular stenosis is an uncommon but debilitating cause of nasal obstruction leading to serious impairment of airway. It is caused by granulation and fibrosis of vestibular lining and there is circumferential scar retraction in the inlet of nasal cavities. Stenosis may be congenital or acquired. Causes of acquired stenosis include burns, trauma, infections, and iatrogenic insult to the lining of vestibule. Surgical correction is usually done by excision of fibrous tissue. A number of studies have been reported on surgical correction but not a single technique is widely accepted due to different diseases and different levels of deformities. Here we are suggesting a technique in which flaps have been raised and scar fibrous tissue is removed. This technique gives a good outcome and satisfactory result in a patient with post traumatic unilateral stenosis.
前庭狭窄是一种罕见但使人衰弱的鼻塞原因,导致气道严重受损。它是由前庭内膜肉芽和纤维化引起的,在鼻腔入口有环形瘢痕缩回。狭窄可能是先天性的或后天的。获得性狭窄的原因包括烧伤、外伤、感染和医源性前庭内层损伤。手术矫正通常通过切除纤维组织来完成。许多关于手术矫正的研究已被报道,但由于不同的疾病和不同程度的畸形,没有一种技术被广泛接受。在这里,我们建议一种将皮瓣抬起并去除疤痕纤维组织的技术。该技术对创伤后单侧狭窄患者有良好的疗效和满意的结果。
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引用次数: 0
Knowledge of Diabetes Mellitus among Undergraduate Clinical Students of Sindh Medical College 信德医学院临床本科生糖尿病知识知晓情况调查
Pub Date : 2022-12-30 DOI: 10.46663/ajsmu.v8i2.47-53
Vikash Kumar, Shahzaib Rehman, N. Jaffar, Nimrah Akram, K. Abbas, Moiz Ahmed
Objective: To determine the knowledge of undergraduate students of Sindh Medical College regarding Diabetes Mellitus (DM) Methodology: This cross sectional study was conducted at Sindh Medical College, Jinnah Sindh Medical University (SMC-JSMU). The participants were students of 3rd year, 4th year and 5th year M.B.B.S. The sample size was calculated to be 282, using open EPI software. The data was collected through a scientifically designed questionnaire which included questions about the over all knowledge, risk factors, complications, diagnosis, treatment, methods of prevention, and WHO criteria of Diabetes Mellitus. SPSS version 22.0 was used for data analysis. Results: About 275 (98%) students had knowledge of the site of insulin production and 255 (90%) knew exactly how insulin produces its effects. Regarding the clinical presentation of DM, 262 (93%) of them agreed that hunger, thirst, and urination present as the major symptoms of this disease (p=0.005). Family history was considered as the prime risk factor by 93 (98%), 83 (95%) and 86 (86%) of final year, fourth, and third year students respectively (p=0.003). Furthermore, 254 (90%) selected retinopathy (p=0.00), 239 (85%) preferred nephropathy (p=0.003) and 224 (79%) considered neuropathy (p=0.024) as the most significant complication of DM. Moreover, the recall of the WHO diagnostic criteria for DM was comparatively lower in final year students (p=0.003). Conclusion: The over all knowledge of undergraduate medical students of Sindh Medical College was found to be satisfactory. Most of the students considered medical education as an adequate source of knowledge in this regard. However, capability of diagnosing DM was found to be comparatively low among final year M.B.B.S. students.
目的:了解信德省医学院本科生对糖尿病(DM)的认知情况。方法学:本横断面研究在真纳信德省医科大学信德省医学院(SMC-JSMU)进行。研究对象为工商管理学院三年级、四年级和五年级的学生,采用开放式EPI软件计算样本量为282人。数据是通过科学设计的问卷收集的,其中包括关于糖尿病的总体知识、危险因素、并发症、诊断、治疗、预防方法和世卫组织标准的问题。采用SPSS 22.0版本进行数据分析。结果:约有275名(98%)学生知道胰岛素产生的部位,255名(90%)学生确切知道胰岛素是如何产生作用的。对于糖尿病的临床表现,262人(93%)认为饥饿、口渴和排尿是糖尿病的主要症状(p=0.005)。三年级、四年级和三年级学生中分别有93人(98%)、83人(95%)和86人(86%)认为家族史是主要危险因素(p=0.003)。此外,254人(90%)选择视网膜病变(p=0.00), 239人(85%)选择肾病(p=0.003), 224人(79%)认为神经病变(p=0.024)是糖尿病最重要的并发症。此外,高年级学生对WHO糖尿病诊断标准的回忆率相对较低(p=0.003)。结论:信德省医学院本科学生对医学知识的总体掌握情况较好。大多数学生认为医学教育是这方面知识的充分来源。然而,最后一年的mba学生诊断糖尿病的能力相对较低。
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引用次数: 0
Gender-Based Frequency and Associated Disability of Rheumatoid Arthritis: A Cross-Sectional Study 基于性别的类风湿关节炎发病率和相关残疾:一项横断面研究
Pub Date : 2022-11-07 DOI: 10.46663/ajsmu.v8i1.26-29
R. Khalid, Komal yasmeen, Aimen shouket, Saira Jahan
Objective: To determine the frequency and associated disability of rheumatoid arthritis in male and female patients Methodology: This was a cross sectional survey conducted at the National Institute of Rehabilitation Science, Pakistan Institute of Medical Science and Pakistan Railways Hospital for one year from February 2019 to February 2020. Study includes diagnosed cases of both genders with ages between 30 to 60 years and fulfilling the 1987 American College of Rheumatology (ACR) criteria. Patients with disabilities due to other reasons were excluded. Sample size of the study was calculated to be 143 using Epi-tool. Sampling technique was non-probability purposive sampling technique. For this study WHODAS-2.0 screening tool was used. Results: Out of 143 patients, 52 (36.4%) were males and 91(63.6%) were females. The mean age of both males and females was 43.41 ± 8.605 SD. We found that 18 (34.6%) male patients presented with mild disability. While in females, 54 (59.3%), 32 (35.16%), 5 (5.49%), and 0 (0%) patients out of 91, reported with mild, moderate, severe, and extreme disabilities respectively. Conclusion: RA is more prevalent in females than in males with the majority of the patients reporting mild disability and more female patients disabled than men.
目的:确定男性和女性患者类风湿关节炎的频率和相关残疾。方法:这是一项横断面调查,于2019年2月至2020年2月在巴基斯坦国家康复科学研究所、巴基斯坦医学科学研究所和巴基斯坦铁路医院进行,为期一年。研究包括年龄在30到60岁之间,符合1987年美国风湿病学会(ACR)标准的男女确诊病例。排除其他原因导致残疾的患者。使用Epi-tool计算本研究的样本量为143。抽样技术为非概率目的抽样技术。本研究采用WHODAS-2.0筛选工具。结果:143例患者中,男性52例(36.4%),女性91例(63.6%)。男女平均年龄为43.41±8.605 SD。我们发现18例(34.6%)男性患者表现为轻度残疾。而在91例女性患者中,分别有54例(59.3%)、32例(35.16%)、5例(5.49%)和0例(0%)报告为轻度、中度、重度和重度残疾。结论:RA在女性中比男性更普遍,大多数患者报告轻度残疾,女性残疾患者多于男性。
{"title":"Gender-Based Frequency and Associated Disability of Rheumatoid Arthritis: A Cross-Sectional Study","authors":"R. Khalid, Komal yasmeen, Aimen shouket, Saira Jahan","doi":"10.46663/ajsmu.v8i1.26-29","DOIUrl":"https://doi.org/10.46663/ajsmu.v8i1.26-29","url":null,"abstract":"Objective: To determine the frequency and associated disability of rheumatoid arthritis in male and female patients Methodology: This was a cross sectional survey conducted at the National Institute of Rehabilitation Science, Pakistan Institute of Medical Science and Pakistan Railways Hospital for one year from February 2019 to February 2020. Study includes diagnosed cases of both genders with ages between 30 to 60 years and fulfilling the 1987 American College of Rheumatology (ACR) criteria. Patients with disabilities due to other reasons were excluded. Sample size of the study was calculated to be 143 using Epi-tool. Sampling technique was non-probability purposive sampling technique. For this study WHODAS-2.0 screening tool was used. Results: Out of 143 patients, 52 (36.4%) were males and 91(63.6%) were females. The mean age of both males and females was 43.41 ± 8.605 SD. We found that 18 (34.6%) male patients presented with mild disability. While in females, 54 (59.3%), 32 (35.16%), 5 (5.49%), and 0 (0%) patients out of 91, reported with mild, moderate, severe, and extreme disabilities respectively. Conclusion: RA is more prevalent in females than in males with the majority of the patients reporting mild disability and more female patients disabled than men.","PeriodicalId":350655,"journal":{"name":"ANNALS of JINNAH SINDH MEDICAL UNIVERSITY","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126272942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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