全身红斑狼疮患者服药依赖性增加

Heppy Roosarina Rahayu Dewi, DetyMulyanti
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摘要

系统性红斑狼疮(SLE)是一种重要的全身自身免疫性疾病。女性患LES的风险是男性的十倍。SLE的病因尚不完全清楚,其病理生理涉及遗传、免疫、内分泌和环境等因素。SLE是一种有缓解期和复发期的慢性疾病,因此需要不同的治疗方法和较长的时间。坚持服药是实现治疗目标的必要条件。根据各种研究,狼疮患者的药物依从率为31.7-45.9%。不坚持治疗SLE导致就诊急诊和住院的增加。影响药物依从性的因素有两种:故意不依从性和非故意不依从性。考虑到这两个因素,需要努力改善和增加药物依从性。
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Peningkatan Kepatuhan Minum Obat Pasien Lupus Eritematosus Sistemik
Systemic Lupus Erythematosus (SLE) is an important systemic autoimmune disease. Women are ten times more at risk of developing LES than men. The etiology of SLE is not fully understood and the pathophysiology involves genetic, immunological, endocrine and environmental factors. SLE is a chronic disease with periods of remission and relapse, so it requires different management and a long time. Medication adherence is required so that treatment goals can be achieved. Medication adherence rates in people with lupus have been reported from various studies to be 31.7-45.9%. Non-adherence to treatment for SLE causes an increase in visits to the emergency department and also hospitalization. There are two kinds of factors that influence medication adherence, intentional non-adherence and non-intentional non-adherence. Efforts are needed to improve and increase medication adherence by considering these both factors.
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