解读氯雷他定在最佳管理和减轻过敏性鼻炎负担中的作用

Nikhil Bangale, Balasubramanyam A M, Nandu Kolwadkar, C. Pereira, Jawahar Bihani, K R Meghanadh, M. Prakash, Monoj Mukherjee, Navin K Patel, P. Singhal, S. Kishore, Uttam Agarwal
{"title":"解读氯雷他定在最佳管理和减轻过敏性鼻炎负担中的作用","authors":"Nikhil Bangale, Balasubramanyam A M, Nandu Kolwadkar, C. Pereira, Jawahar Bihani, K R Meghanadh, M. Prakash, Monoj Mukherjee, Navin K Patel, P. Singhal, S. Kishore, Uttam Agarwal","doi":"10.18231/j.ijoas.2022.029","DOIUrl":null,"url":null,"abstract":"Despite an alarmingly rise in prevalence of allergic rhinitis in the last 2 decades, yet till date it remains underdiagnosed, undertreated, or mistreated in India. The distinguishing features of allergic rhinitis are commonly misinterpreted with the common cold and thus early detection of allergic rhinitis is often delayed in primary care. Poorly controlled allergic rhinitis adversely impairs overall long-term productivity at work or school, quality of life (QoL) and can also trigger underlying comorbidities like asthma. Thus, early diagnosis and timely referral is the need of the hour for more effective management which will reduce the overall burden of allergic rhinitis in India. As allergic rhinitis needs long-term management, it is also paramount to prescribe highly efficacious, cost-effective treatment with minimal side effects like drowsiness to prevent disruption of patient’s QoL. However, current therapies including intranasal corticosteroids have adverse long-term complications and antihistamines like cetirizine, levocetirizine, and fexofenadine have varying degrees of sedation.With these concerns, a management algorithm was developed to aid for early diagnosis in primary care which provides cost effective option of right medication for a proper duration of time to optimize overall patient care. After a thorough discussion of key opinion leaders and evidence-based recommendations, it was highlighted that loratadine deserves to be considered as a first-line antihistamine therapy due to its rapid and long-lasting symptom relief, non drowsy, and low complication rate for long-term management of allergic rhinitis.","PeriodicalId":166713,"journal":{"name":"IP Journal of Otorhinolaryngology and Allied Science","volume":"140 11 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Decoding the role of loratadine in optimally managing and in alleviating the burden of allergic rhinitis\",\"authors\":\"Nikhil Bangale, Balasubramanyam A M, Nandu Kolwadkar, C. Pereira, Jawahar Bihani, K R Meghanadh, M. Prakash, Monoj Mukherjee, Navin K Patel, P. Singhal, S. Kishore, Uttam Agarwal\",\"doi\":\"10.18231/j.ijoas.2022.029\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Despite an alarmingly rise in prevalence of allergic rhinitis in the last 2 decades, yet till date it remains underdiagnosed, undertreated, or mistreated in India. The distinguishing features of allergic rhinitis are commonly misinterpreted with the common cold and thus early detection of allergic rhinitis is often delayed in primary care. Poorly controlled allergic rhinitis adversely impairs overall long-term productivity at work or school, quality of life (QoL) and can also trigger underlying comorbidities like asthma. Thus, early diagnosis and timely referral is the need of the hour for more effective management which will reduce the overall burden of allergic rhinitis in India. As allergic rhinitis needs long-term management, it is also paramount to prescribe highly efficacious, cost-effective treatment with minimal side effects like drowsiness to prevent disruption of patient’s QoL. However, current therapies including intranasal corticosteroids have adverse long-term complications and antihistamines like cetirizine, levocetirizine, and fexofenadine have varying degrees of sedation.With these concerns, a management algorithm was developed to aid for early diagnosis in primary care which provides cost effective option of right medication for a proper duration of time to optimize overall patient care. After a thorough discussion of key opinion leaders and evidence-based recommendations, it was highlighted that loratadine deserves to be considered as a first-line antihistamine therapy due to its rapid and long-lasting symptom relief, non drowsy, and low complication rate for long-term management of allergic rhinitis.\",\"PeriodicalId\":166713,\"journal\":{\"name\":\"IP Journal of Otorhinolaryngology and Allied Science\",\"volume\":\"140 11 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IP Journal of Otorhinolaryngology and Allied Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18231/j.ijoas.2022.029\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IP Journal of Otorhinolaryngology and Allied Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/j.ijoas.2022.029","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

尽管过敏性鼻炎的患病率在过去二十年中出现了惊人的上升,但迄今为止,在印度仍未得到充分的诊断、治疗或治疗。变应性鼻炎的特征通常被误认为是普通感冒,因此早期发现变应性鼻炎往往延迟在初级保健。控制不佳的过敏性鼻炎会对工作或学习的整体长期生产力、生活质量(QoL)产生不利影响,还可能引发哮喘等潜在合并症。因此,早期诊断和及时转诊是更有效管理的需要,这将减少印度过敏性鼻炎的总体负担。由于过敏性鼻炎需要长期治疗,因此最重要的是要开出高效、经济的治疗方案,同时尽量减少副作用,如嗜睡,以防止患者的生活质量受到影响。然而,目前包括鼻内皮质类固醇在内的治疗方法存在不良的长期并发症,而西替利嗪、左西替利嗪和非索非那定等抗组胺药具有不同程度的镇静作用。考虑到这些问题,我们开发了一种管理算法,以帮助初级保健的早期诊断,在适当的时间内提供具有成本效益的正确药物选择,以优化患者的整体护理。经过对主要意见领袖和循证建议的深入讨论,强调氯雷他定因其快速持久的症状缓解、不嗜睡、并发症发生率低而值得考虑作为一线抗组胺药治疗变应性鼻炎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Decoding the role of loratadine in optimally managing and in alleviating the burden of allergic rhinitis
Despite an alarmingly rise in prevalence of allergic rhinitis in the last 2 decades, yet till date it remains underdiagnosed, undertreated, or mistreated in India. The distinguishing features of allergic rhinitis are commonly misinterpreted with the common cold and thus early detection of allergic rhinitis is often delayed in primary care. Poorly controlled allergic rhinitis adversely impairs overall long-term productivity at work or school, quality of life (QoL) and can also trigger underlying comorbidities like asthma. Thus, early diagnosis and timely referral is the need of the hour for more effective management which will reduce the overall burden of allergic rhinitis in India. As allergic rhinitis needs long-term management, it is also paramount to prescribe highly efficacious, cost-effective treatment with minimal side effects like drowsiness to prevent disruption of patient’s QoL. However, current therapies including intranasal corticosteroids have adverse long-term complications and antihistamines like cetirizine, levocetirizine, and fexofenadine have varying degrees of sedation.With these concerns, a management algorithm was developed to aid for early diagnosis in primary care which provides cost effective option of right medication for a proper duration of time to optimize overall patient care. After a thorough discussion of key opinion leaders and evidence-based recommendations, it was highlighted that loratadine deserves to be considered as a first-line antihistamine therapy due to its rapid and long-lasting symptom relief, non drowsy, and low complication rate for long-term management of allergic rhinitis.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Massive mandibular ameloblastoma masquerading malignancy: A unique case A case report on use of ivermectin as nasal drop in a case of nasal myiasis Cocktail regimen in treatment of sudden sensorineural hearing loss Nasopharyngeal carcinoma in a young adolescent with unilatral palatal palsy and neck mass – A rare case report Biofilms in the middle ear: Unveiling challenges and solutions
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1