控制呼吸过程中心率变异性的计算细胞模型

N. Sadowski, G. Drzewiecki
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引用次数: 0

摘要

窦房结(SAN)位于右心房壁上,是心脏的生物起搏器,通过心脏起搏器细胞中心脏节律性收缩的重复自发动作电位来决定心率。趣味电流(If)和SAN在交感神经系统和副交感神经系统的调控下,共同调节SAN动作电位的频率。这些系统的相互作用负责节律性起搏器活动,控制心率和导致心律失常的异常。
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Computational Cellular Model of Heart Rate Variability During Controlled Respiration
The sinoatrial node (SAN), located in the right atrium wall, is the heart's biological pacemaker and determines heart rate due to the repetitive spontaneous action potentials for cardiac rhythmic contractions in the heart pacemaker cells. The funny current (If) and SAN, together with regulation by the sympathetic and parasympathetic nervous systems, modulate the frequency of the SAN action potential. The interaction of these systems is responsible for the rhythmic pacemaker activity, controlling heart rate, and abnormalities resulting in arrhythmias.
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