忆阻器在细胞形态系统中的人工生化反应

Hanna Abo Hanna, Loai Danial, Shahar Kvatinsky, Ramez Daniel
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引用次数: 2

摘要

忆阻器是一种纳米级双端随机电子器件。本文提出了生化反应与记忆装置之间的功能类比。研究表明,忆阻器可以有效地模拟生物化学反应和基因网络,并在纳米尺度上捕获确定性和随机动力学。我们提出了不同的抽象模型和压控电阻开关电路,这些模型固有地模拟了低信噪比(SNR)遗传电路的活动。这些发现为具有耐噪声和节能特性的细胞启发电路设计提供了一个里程碑,为研究系统和合成生物学中的任意大规模生物网络提供了一个快速、简单的模拟框架。
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Memristors as Artificial Biochemical Reactions in Cytomorphic Systems
A memristor is a nano-scale two-terminal stochastic electronic device. This paper proposes functional analogies between biochemical reactions and memristive devices. It shows that memristors can mimic biochemical reactions and gene networks efficiently and capture both deterministic and stochastic dynamics at the nano-scale level. We present different abstraction models and voltage-controlled resistive switching circuits that inherently model the activity of genetic circuits with low signal-to-noise ratio (SNR). These findings constitute a milestone for cell-inspired circuit design with noise-tolerance and energy-efficiency features, which can provide a fast and simple emulative framework for studying arbitrary large-scale biological networks in systems and synthetic biology.
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