{"title":"免疫系统病理学中使用的免疫抑制剂。1 .环孢素、环磷素、硫唑嘌呤和巯基嘌呤。","authors":"Iu K Napolov, K B Borisov","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The data on immunodepressants most commonly used in the Soviet Union in the diseases caused by disorders in normal function of the immune system are presented. Such drugs as cyclosporine A, cyclophosphan, azatioprine, 6-mercaptopurine are considered. Emphasis is given to the mechanism of the primary pharmacological response of the drugs to the immunocompetent cells, the grounding of their clinical use, dosage and mechanisms of possible side effects.</p>","PeriodicalId":12237,"journal":{"name":"Farmakologiia i toksikologiia","volume":"54 4","pages":"80-7"},"PeriodicalIF":0.0000,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Immunodepressants used in immune system pathology. I. Cyclosporin, cyclophosphane, azathioprine and mercaptopurine].\",\"authors\":\"Iu K Napolov, K B Borisov\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The data on immunodepressants most commonly used in the Soviet Union in the diseases caused by disorders in normal function of the immune system are presented. Such drugs as cyclosporine A, cyclophosphan, azatioprine, 6-mercaptopurine are considered. Emphasis is given to the mechanism of the primary pharmacological response of the drugs to the immunocompetent cells, the grounding of their clinical use, dosage and mechanisms of possible side effects.</p>\",\"PeriodicalId\":12237,\"journal\":{\"name\":\"Farmakologiia i toksikologiia\",\"volume\":\"54 4\",\"pages\":\"80-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Farmakologiia i toksikologiia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Farmakologiia i toksikologiia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Immunodepressants used in immune system pathology. I. Cyclosporin, cyclophosphane, azathioprine and mercaptopurine].
The data on immunodepressants most commonly used in the Soviet Union in the diseases caused by disorders in normal function of the immune system are presented. Such drugs as cyclosporine A, cyclophosphan, azatioprine, 6-mercaptopurine are considered. Emphasis is given to the mechanism of the primary pharmacological response of the drugs to the immunocompetent cells, the grounding of their clinical use, dosage and mechanisms of possible side effects.
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