【卡利普索尔胚胎毒性作用的特点】。

Farmakologiia i toksikologiia Pub Date : 1991-09-01
Iu I Bandazhevskiĭ, A I Shimanovich
{"title":"【卡利普索尔胚胎毒性作用的特点】。","authors":"Iu I Bandazhevskiĭ,&nbsp;A I Shimanovich","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effect of calipsol on the course of pregnancy and the embryonal development in albino rats was studied. It was found that single injections of the drug in a dose of 200 mg/kg on the 7th or 8th day of pregnancy induced no disorders in the pregnancy course and the embryonal development. At the administration in a dose of 40.0 mg/kg on the 11th, 13th, 15th days of pregnancy calipsol was shown to exert a marked embryolethal action and at the administration on the 7th, 9th, 11th days of pregnancy in doses of 20 and 40 mg/kg increased the number of fetuses with hemorrhages into the internal organs.</p>","PeriodicalId":12237,"journal":{"name":"Farmakologiia i toksikologiia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The characteristics of the embryotoxic action of kalipsol].\",\"authors\":\"Iu I Bandazhevskiĭ,&nbsp;A I Shimanovich\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The effect of calipsol on the course of pregnancy and the embryonal development in albino rats was studied. It was found that single injections of the drug in a dose of 200 mg/kg on the 7th or 8th day of pregnancy induced no disorders in the pregnancy course and the embryonal development. At the administration in a dose of 40.0 mg/kg on the 11th, 13th, 15th days of pregnancy calipsol was shown to exert a marked embryolethal action and at the administration on the 7th, 9th, 11th days of pregnancy in doses of 20 and 40 mg/kg increased the number of fetuses with hemorrhages into the internal organs.</p>\",\"PeriodicalId\":12237,\"journal\":{\"name\":\"Farmakologiia i toksikologiia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1991-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Farmakologiia i toksikologiia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Farmakologiia i toksikologiia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

研究了卡利普索尔对白化大鼠妊娠过程及胚胎发育的影响。在妊娠第7天或第8天单次注射剂量为200 mg/kg的药物对妊娠过程和胚胎发育无影响。在妊娠第11、13、15天给药剂量为40.0 mg/kg时,显示出明显的胚胎死亡作用,在妊娠第7、9、11天给药剂量为20和40 mg/kg时,内脏出血的胎儿数量增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
[The characteristics of the embryotoxic action of kalipsol].

The effect of calipsol on the course of pregnancy and the embryonal development in albino rats was studied. It was found that single injections of the drug in a dose of 200 mg/kg on the 7th or 8th day of pregnancy induced no disorders in the pregnancy course and the embryonal development. At the administration in a dose of 40.0 mg/kg on the 11th, 13th, 15th days of pregnancy calipsol was shown to exert a marked embryolethal action and at the administration on the 7th, 9th, 11th days of pregnancy in doses of 20 and 40 mg/kg increased the number of fetuses with hemorrhages into the internal organs.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
[An analysis of the age-related characteristics of the analgesic action of clofelin]. [Neuroendocrine and immunological interactions in chronic alcoholism]. [The history of the Department of Pharmacology of the Kiev Medical Institute]. [The genetically determined polymorphism of metabolic oxidation of the sparteine-debrisoquin type]. [Nuclear magnetic resonance in pharmacology].
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1