[The use of obzidan and metoprolol in patients with supraventricular systolic tachyarrhythmias].

Having analyzed the electrophysiological mechanisms and state of humoral regulatory substances in 87 patients with paroxysmal disorders of the cardiac rhythm the authors determined the antiarrhythmic action of two beta-blockaders: obsidan and metoprolol. They found a reduction of the sinus node function under the effect of obsidan and to a lesser degree under the effect of metoprolol. Metoprolol produced a high antiarrhythmic effect, particularly in supraventricular tachycardias with participation of abnormal conduction pathways.