基于MR图像和血流模拟建立主动脉弓的CFD模型

D. Mori, Takami Yamaguchi
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引用次数: 13

摘要

人类主动脉弓除了曲率大外,还有明显的扭转。以前的一些临床观察指出,扭转可能与胸动脉瘤的发展有关。众所周知,扭转影响血液流动,这被怀疑与各种血管疾病有关。本研究基于一组磁共振图像,建立了人体主动脉弓的三维计算流体动力学(CFD)模型,并对动脉弓内的血流进行了模拟。结果表明:主动脉弓中心线的扭转导致主动脉弓顶部壁面剪应力具有复杂的局部分布;基于MRI的建模被证明是研究血流计算流体力学分析的有力手段。
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Construction of the CFD model of the aortic arch based on MR images and simulation of the blood flow
The human aortic arch has significant torsion in addition to its large curvature. It was previously pointed out from some clinical observations that the torsion may be related to the development of the thoracic aneurysms. It is also known that the torsion affects the blood flow, which is suspected to be associated with various vascular diseases. In this study, a realistic three-dimensional computational fluid dynamics (CFD) model of a human aortic arch was constructed based on a set of MR images and the blood flow in the arch was simulated. The results showed that the torsion of the aortic arch centerline led to a complex localized distribution of the wall shear stress at the top of the arch. MRI based modeling was shown to be a powerful means to investigate computational fluid mechanical analysis of the blood flow.
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