COVID-19大流行期间封锁和临床实践变化对血糖控制的影响:来自卡塔尔多哈国家糖尿病中心的数据分析

Buthaina Alowainati, Z. Dabbous, Obada Salameh, Mohammad Hamad, Layla Al Hail, Wajeeha Abuheliqa, Ibrahim Al-Janahi, A. Jayyousi, M. Zirie
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引用次数: 1

摘要

导语:2019冠状病毒病(COVID-19)大流行与改变生活方式和临床实践的国际义务有关。这些变化对糖尿病患者来说是令人担忧的,因为日常生活的中断会对血糖控制产生毁灭性的影响。本回顾性研究旨在评估封锁的影响和制定的患者管理变化对血糖控制的效果。方法:1型糖尿病(T1DM)和2型糖尿病(T2DM)患者在国家糖尿病中心接受远程医疗管理,封锁期超过3个月。作为标准治疗的一部分,对他们进行的血液检查进行了回顾。结果:共纳入509例患者。封城后,49.5%的患者HbA1c略有下降(P = 0.42)。在封锁期间,非高血压患者的HbA1c显著降低(校正优势比[ORa]: 0.59, 95%可信区间[CI]: 0.39-0.91, P = 0.018)。还确定了身体质量指数(BMI)与封锁后较低的HbA1c水平之间的显著关联(ORa: 0.95, (95% CI: 0.92-0.98, P = 0.001)。只有体重正常的BMI组有显著的HbA1c降低(平均值:0.46±0.3,P = 0.03)。结论:新冠肺炎强制封城对T1DM和T2DM患者的HbA1c水平和血糖控制没有不利影响。相反,在封锁期后,体重和血压正常的患者的HbA1c有所改善。
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The impact of lockdown and changes in clinical practice on glycemic control during the COVID-19 pandemic: Analysis of data from the National Diabetes Center, Doha, Qatar
Introduction: The coronavirus disease-2019 (COVID-19) pandemic was associated with international obligations that modified lifestyles and clinical practice. These changes are worrisome for patients with diabetes, as disruption from a routine can have devastating effects on glucose control. This retrospective study aims to assess the impact of lockdown and the efficacy of the instituted changes in patient management on blood sugar control. Methods: Patients with type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) who received management through telemedicine at the National Diabetes Center over a lockdown period of 3 months were included. The blood investigations that were done for them as part of standard care were reviewed. Results: A total of 509 patients were included. HbA1c slightly decreased in 49.5% of the patients after the lockdown (P = 0.42). Patients who were not hypertensive experienced a significant reduction in HbA1c (adjusted odds ratios [ORa]: 0.59, 95% confidence interval [CI]: 0.39–0.91, P = 0.018) during the lockdown. A significant association between body mass index (BMI) and lower HbA1c level postlockdown was also determined (ORa: 0.95, (95% CI: 0.92–0.98, P = 0.001). A significant HbA1c reduction was only noted in the BMI group of normal weight (mean: 0.46 ± 0.3, P = 0.03). Conclusion: The imposed lockdown due to COVID-19 did not adversely impact the HbA1c level and glycemic control in T1DM and T2DM patients. Inversely, HbA1c improvements were determined in patients with normal weight and blood pressure after the lockdown period.
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