平乌伦镇城市成年人代谢危险因素及相关发病率

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摘要

代谢综合征是2型糖尿病和心血管疾病的一组危险因素,胰岛素抵抗被认为是一个联系因素。它在世界范围内很常见,而且发病率正在上升,主要归因于日益增加的肥胖和久坐不动的生活方式,现在既是一个公共卫生问题,也是一个临床问题。这项基于社区的横断面描述性研究于2015年进行,旨在确定Pyin Oo Lwin镇成年城市人群的代谢危险因素和相关发病率。共纳入355名参与者,94名男性(26.5%)和261名女性(73.5%)。年龄分布18 ~ 85岁,平均49.98岁(SD:15.22)。根据国家胆固醇教育计划成人治疗小组III (NCEP ATP III)指南确定代谢危险因素。在这项研究中,中心性肥胖是最高的组成部分,有145人(40.8%),其次是甘油三酯升高129人(36%)。3%),血压升高104人(29.3%),低高密度脂蛋白胆固醇85人(23.9%),空腹血糖升高仅48人(13.5%)。代谢综合征总患病率为35.2%,其中男性26.6%,女性38.3%。以上5种代谢危险因素与代谢综合征的相关性均有统计学意义(p值<0.001)。在相关发病方面,心电图检查正常296例(83.4%),异常59例(16.6%),但代谢综合征与异常心电图无显著性差异。总之,这项研究认识到代谢综合征的高患病率,可以将代谢风险描述为开展进一步活动以减少非传染性疾病发病率的基线数据。
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Metabolic Risk Factors and Associated Morbidities among Adult Urban People in Pyin Oo Lwin Township
Metabolic syndrome is a cluster of risk factors for type 2 diabetes and cardiovascular disease, with insulin resistance proposed as a linking factor. It is common and is increasing in prevalence worldwide, largely attributed to increasing obesity and sedentary lifestyles, and now is both a public health and clinical problem. This community-based, cross-sectional descriptive study was conducted during 2015 to identify metabolic risk factors and associated morbidities among adult urban people in Pyin Oo Lwin Township. A total of 355 participants, 94 men (26.5%) and 261 women (73.5%) were enrolled. Age distribution was from 18 to 85 years with mean of 49.98 (SD:15.22) years. Metabolic risk factors were identified according to National Cholesterol Education Programme Adult Treatment Panel III (NCEP ATP III) guideline. In this study, central obesity was the highest component with 145 subjects (40.8%) followed by elevated triglycerides 129(36. 3%), elevated blood pressure 104(29.3%), low HDL-cholesterols 85(23.9%), and elevated fasting glucose in only 48 individuals (13.5%). The total prevalence of metabolic syndrome was 35.2% with 26.6% in men and 38.3% in women, respectively. There were statistically significant associations above all five metabolic risk factors with metabolic syndrome (p value <0.001). Regarding its associated morbidities, ECG examinations showed normal 296 cases (83.4%) and abnormal in 59 cases (16.6%) but there was no significant difference between metabolic syndrome and abnormal ECG findings. In conclusion, this study recognizes the high prevalence rate of metabolic syndrome and can be depicted about the metabolic risks as the baseline data for implementation of further activities to reduce the incidence of non-communicable diseases.
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