氧化纳米线生物传感器

K. Jeon, H. J. Son, C. E. Kim, M. Shon, K. Yoo, A.M. Choi, H.I. Jung, Sang Yeol Lee
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引用次数: 3

摘要

在真空炉中采用简单的物理气相沉积法在p-Si(100)衬底上制备了ZnO纳米线。扫描电镜(SEM)结果表明,ZnO NWs的直径在20 ~ 50 nm之间,平均长度大于2 nm。室温光致发光光谱显示近带边发射和深能级绿光发射。结果表明所制备的纳米线具有良好的结构质量。我们制作了基于ZnO NW场效应晶体管的电生物传感器,并报道了ZnO NW的化学灵敏度。生物素功能化的ZnO纳米传感器可以方便地检测链霉亲和素的结合。ZnO NWs可用于灵敏、无标记、实时检测多种生物物种,可用于体内诊断。
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Biosensor with Oxide Nanowires
ZnO nanowires (NWs) were fabricated on p-Si (100) substrates by simple physical vapor deposition in vacuum furnace. Scanning electron microscopy (SEM) images indicate that the diameters of ZnO NWs were from 20 to 50 nm and the average length was longer than 2 mum. Room-temperature photoluminescence spectra of the NWs show the near band-edge emissions and the deep-level green light emissions. Such result indicates that the nanowires have good structural quality. We have fabricated electrical biosensors based on ZnO NW field effect transistors and report the chemical sensitivity of ZnO NWs. The ZnO nanosensor functionalized with biotin can easily detect streptavidin binding. The ZnO NWs for sensitive, label-free, real time detection of a wide range of biological species could be exploited in vivo diagnostics.
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