慢性阻塞性肺疾病患者呼气峰流速与手部动力学的相关性:病例对照研究

Erum Afaq, Muhammed Nisar, Muhammad Irfan, Syed Hafeez-ul- Hassan, Talha Ahmed
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摘要

目的:确定慢性阻塞性肺疾病患者呼气峰流速与手部动力学的相关性,并了解病例与对照组的握力差异。方法学:本研究于2019年7月1日至2020年6月30日在利亚奎特国立医院医学院生理科和胸内科进行,经该医院研究和伦理委员会批准。我们采用了有目的的抽样技术。总共招募了100名同意的个体,将其平均分为对照组和慢性阻塞性肺疾病组。测量了人体测量值以及呼气峰值流速和手动力测量值。结果:与对照组相比,慢性阻塞性肺疾病患者的握力和呼气峰流速有显著性差异,慢性阻塞性肺疾病患者的呼气峰流速和握力明显降低。呼气流量峰值与握力呈弱相关,p值显著。腰臀比与握力之间没有关系。身体质量指数与握力呈弱负相关,但有统计学意义。结论:慢性阻塞性肺疾病患者手部握力下降,确定手部握力可确保快速评估生活质量。
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The Correlation of Peak Expiratory Flow Rate and Hand Dynamometry in Chronic Obstructive Pulmonary Disease Patients A Case Control study
Objectives: To determine the correlation of peak expiratory flow rate and hand dynamometry in patients with chronic obstructive pulmonary disease and to find out the differences between hand grip in cases and control group Methodology: This study was carried out in the Department of Physiology and Department of Chest Medicine, Liaquat National Hospital and Medical College between July 1st 2019 and June 30th 2020 after the approval of the research and ethical committee of the same hospital. We used purposive sampling technique. Total 100 consenting individuals were recruited that were equally divided into control group and chronic obstructive pulmonary disease group. Anthropometric measurements alongwith peak expiratory flow rate and hand dynamometry values were measured. Results: We found significant difference in hand grip strength and peak expiratory flow rate between the case and control groups, chronic obstructive pulmonary disease patients have decreased peak expiratory flow rate and handgrip strength. Weak correlation exists between peak expiratory flow rate and hand grip strength with significant p value. No relationship was found between waist hip ratio and hand grip. Also, body mass index showed a weak negative but statistically significant correlation with hand grip strength. Conclusion: In chronic obstructive pulmonary disease patients, hand grip strength is decreased and determining hand grip strength may ensures quick assessment of quality of life.
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