Phytochemical Analysis and Evaluation of Anti-inflammatory Activity of Bignonia venusta(Ker Gawl.) Miers Flower Extracts

Abstract-The inflammatory response involves a complex array of enzyme activation, mediator release, fluid extra vasations, cell migration, tissue breakdown and repair which are aimed at host defence and usually activated in disease condition. Currently much interest has been shown in the searching of medicinal plants with anti-inflammatory activity which may lead to the discovery of new therapeutic agent that is not only used to suppress the inflammation but also used in diverse disease conditions where the inflammation response is amplifying in the disease process. In the present study, the selectionofBignoniavenustaplantforevaluation was based on its traditional usages. Preparation of different extracts from non polar and polar solvent were prepared to study the phytochemical analysis in different extracts and antiinflammatoryactivitiesofdifferentextracts. Methanol extract was found to be the richest extract for phytoconstituents and from the comparison with the standard drug aspirin, it was observed that the concentration of 2000 μg/ml of methanol extract showed maximum activity (58.0%) at 560 nm while the other extract from petroleum ether, in comparison with standard drug aspirin shows no activity.