高压氧治疗治疗院内感染的有益效果。病例报告及简短文献回顾

Cristina-Elena Micu, R. Smărăndescu, I. Arghir, Mihaela Trenchea, Bogdan-Alexandru Barbu, C. Handra
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引用次数: 1

摘要

新型冠状病毒SARS-CoV-2感染于2020年初被宣布为全球突发卫生事件,两个月后成为公认的大流行,不分年龄、种族、地理区域影响全球人口。COVID-19通常表现为全身状况改变(发烧、发冷、明显疲劳、肌肉疼痛、头痛)、咳嗽、呼吸困难等呼吸系统症状、急性呼吸窘迫以及严重形式的多器官损伤。症状可在接触后2天至2周内出现,从轻度症状发展到中度、严重甚至致命形式。我们报告的COVID-19临床病例是一名59岁的护士,糖尿病和高血压是危险因素。由于在有治疗床位的设施中未遵守现有的换衣防护设备规程,意外职业暴露于SARS-CoV-2感染。我们诊断为中重度COVID-19,表现为双侧肺损伤和轻度去饱和,合并克雷伯氏杆菌的细菌重复感染,患者住院期间接受了抗病毒、抗生素、抗凝血剂、可的松治疗。在出院后的头两个月,我们推荐7次高压氧治疗,以缓解呼吸道症状,促进纤维化肺病变的消退。
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Beneficial effect of hyperbaric oxygen therapy in solving a nosocomial COVID-19 infection. Case report and short literature review
Abstract The infection with the new coronavirus SARS-CoV-2 was declared a global health emergency in early 2020 and, two months later, became recognized as a pandemic, affecting the world’s population regardless of age, ethnicity, geographical area. COVID-19 generally presents with altered general condition (fever, chills, marked fatigue, muscle aches, headache), respiratory manifestations from cough to dyspnea, acute respiratory distress, and multiorgan damage in critical forms. Manifestations can occur between 2 days and two weeks after exposure, the disease evolving from mildly symptomatic to moderate, severe, and even fatal forms. Our reported clinical case of COVID-19 is that of a 59-year-old nurse with diabetes and hypertension as risk factors. Accidental occupational exposure to SARS-CoV-2 infection occurred due to non-compliance with the existing dressing-undressing protective equipment protocols in facilities with treatment beds. We diagnosed a moderate-severe COVID-19, displaying bilateral lung damage and mild desaturation, complicated by bacterial superinfection with Klebsiella spp. The patient underwent antiviral, antibiotic, anticoagulant, cortisone treatment during hospitalization. In the first two months after discharge, we recommended seven hyperbaric therapy sessions to relieve respiratory symptoms and enhance regression of fibrotic lung lesions.
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