提供扩大免疫计划(EPI)的医疗中心麻疹疫苗成本效益分析的相关性和决定因素

Mehak Nimra, Hamza Irshad, Muhammad Murtaza Hasnain, Sheikh Muhammad Ishaque
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摘要

麻疹是一种高度传染性的病毒感染,疫苗可预防的疾病每年夺去全世界近3000万人的生命,其中包括17%的5岁以下儿童。方法:这是一项描述性和横断面调查。采用回顾性资料收集。我们考察了提供EPI管理的医疗中心。结果:根据健康中心的记录,研究中约有8%的年轻人被发现患有麻疹。感染麻疹的儿童人数尚未确定。只有12%的受访者接种了麻疹疫苗,绝大多数(88%)从未接种过疫苗。经统计分析,本研究的r平方值为r=0.35,认为是中间直接关系(疫苗浪费与总成本)。它表明,如果没有对疫苗浪费进行制衡的制度,就可能对疫苗接种的总体成本产生影响。疫苗浪费与剂量浪费呈正相关,x2= 438.8 (p值0.002)。疫苗瓶破损x2 = 369.6 (p值0.015),疫苗过期x2 = 1068 (p值0.006),冷链维护x2 = 79.99 (p值0.014),库存缺失x2 = 646.9 (p值0.004),均有统计学意义。结论:任何一种疾病的消除都是由平行因素促成的,其中一个因素也包括经济状况。我们可以用更少的时间和成本为许多儿童接种疫苗,并实现免疫接种的普遍覆盖。
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The correlation and determinants of cost-benefit analysis of measles vaccines among the medical centers providing Expanded Program on Immunization (EPI)
Introduction: Measles is a highly contagious viral infection, vaccine-preventable diseases claim the lives of nearly 30 million people each year around the world, including 17% of children under the age of 5. Methodology: This was a descriptive and cross-sectional investigation. Retrospective data collection was used. We looked at medical centers that provided EPI administrations. Results: Around 8% of the youngsters in the study were found to have measles, according to the health center's records. There are an undetermined number of measles-infected children. Only 12% of those surveyed had received the measles vaccine, and the vast majority (88%) had never received the shot. According to statistical analysis, the study's r square value is r=0.35, which is considered to be an intermediate direct relationship (Wastage of vaccine and total cost). It illustrates that if there is no system of checks and balances on vaccine waste, it could have an impact on the overall cost of the vaccination. Vaccines wastage shows a positive association with Dose wastage x2= 438.8 (p-value 0.002). the breakage of vaccine vial x2 = 369.6 (p-value 0.015), expiration of vaccines x2 = 1068 (p-value 0.006), cold chain maintenance x2 = 79.99 (p-value 0.014) & inventory missing was x2 646.9 (p-value 0.004) showed statistical significance. Conclusion: The elimination of any disease would be contributed by the parallel factors one of that includes also financial state. In less time and cost we can vaccinate the number of children and can achieve universal coverage of immunization.
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