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Trichobezoar: A case report of a hairball in the stomach 毛癣:胃中出现毛球1例
Pub Date : 2023-07-09 DOI: 10.32593/jstmu/vol6.iss1.228
Fatima Khurshid, Muzzamal Hussain, Ans Abdul Razzaq
Trichobezoar is an underdiagnosed condition that should be considered in children and teenagers, particularly girls. According to a late diagnosis, trichobezoars can result in gastrointestinal bleeding or perforation. In this report, we discussed a 14-year-old girl who presented with severe abdominal pain with a well-defined mass in the Epigastrium; a CT scan revealed a giant mass with stomach distension which was removed through Gastrotomy. Gastric bezoars that are misdiagnosed could have life-threatening effects. Effective screening is necessary for early diagnosis. It is crucial to receive medical counselling to avoid a recurrence of bezoar.
毛癣是一种未被诊断的疾病,应该在儿童和青少年,特别是女孩中加以考虑。根据晚期诊断,毛虫可导致胃肠道出血或穿孔。在这个报告中,我们讨论了一个14岁的女孩,她表现为严重的腹痛,并在上腹部有明显的肿块;CT扫描显示一个巨大的肿物并伴有胃膨胀,并通过胃切开术切除。胃牛黄被误诊可能会危及生命。有效的筛查是早期诊断的必要条件。接受医疗咨询以避免牛黄复发是至关重要的。
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引用次数: 0
Melody of sleep by sun: Association between serum vitamin D levels and sleep quality in ESRD patients. 阳光下睡眠的旋律:ESRD患者血清维生素D水平与睡眠质量的关系。
Pub Date : 2023-07-09 DOI: 10.32593/jstmu/vol6.iss1.233
Zoha Fatima, Ujala Abdul Rashid, Umara Nasim, Hafiza Amina Muattar
Background: Hemodialysis (HD) is a commonly employed treatment modality for chronic kidney disease (CKD) patients. It is also closely related to the sleep-wake cycle. It has both sleep-improving and deteriorating results. Sleep regulation is tightly coupled to vitamin D; hence, its deficiency might impact the duration and quality of sleep. This study intends to evaluate the association between sleep quality and serum vitamin D levels in HD patients. Objective: To assess the quality of sleep in patients with ESRD on routine HD and determine the association of vitamin D deficiency with sleep quality. Methodology: This cross-sectional analytical study was conducted on the patients presenting to the dialyzing centre of the Department of Nephrology, Holy Family Hospital, Rawalpindi, Pakistan, for twice-weekly routine hemodialysis, from May 2022 to June 2022.  Results: In this study, the quality of sleep in End Stage Renal Disease (ESRD) patients on twice-weekly hemodialysis (HD) was assessed using the PSQI score. PSQI scores were associated with serum vitamin D levels in these patients. A significantly strong positive correlation existed between serum levels of 25-OH D and sleep quality (r = −0.468, p = 0.001). Conclusion: More than half of the patients undergoing routine hemodialysis could not sleep well at night. Among other related factors, vitamin D deficiency was an independent risk factor for poor sleep quality. Further studies are needed to determine the impact of vitamin D supplementation on improving sleep quality to strengthen the association between vitamin D levels and sleep disorders.
背景:血液透析(HD)是慢性肾脏疾病(CKD)患者常用的治疗方式。它也与睡眠-觉醒周期密切相关。它既有改善睡眠的效果,也有恶化睡眠的效果。睡眠调节与维生素D密切相关;因此,它的缺乏可能会影响睡眠的持续时间和质量。本研究旨在评估HD患者睡眠质量与血清维生素D水平之间的关系。目的:评价终末期肾病常规HD患者的睡眠质量,探讨维生素D缺乏与睡眠质量的关系。方法:这项横断面分析研究是对2022年5月至2022年6月期间在巴基斯坦拉瓦尔品第圣家医院肾内科透析中心就诊、每周进行两次常规血液透析的患者进行的。结果:在本研究中,使用PSQI评分评估终末期肾病(ESRD)患者每周两次血液透析(HD)的睡眠质量。PSQI评分与这些患者的血清维生素D水平相关。血清25-OH - D水平与睡眠质量呈显著正相关(r = - 0.468, p = 0.001)。结论:半数以上的常规血液透析患者夜间睡眠不好。在其他相关因素中,维生素D缺乏是睡眠质量差的独立风险因素。需要进一步的研究来确定补充维生素D对改善睡眠质量的影响,以加强维生素D水平与睡眠障碍之间的联系。
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引用次数: 0
A retrospective study on epidemiological and clinical characteristics of COVID-19 in Baluchistan (Pakistan) and its future perspectives 巴基斯坦俾路支省新冠肺炎流行病学和临床特征的回顾性研究及未来展望
Pub Date : 2023-07-09 DOI: 10.32593/jstmu/vol6.iss1.226
Sadiah Sabir, N. Sabir, Ayesha Mushtaq, Merman Gul, M. Khan
Background: The rise of a viral respiratory sickness was recognized in China and later known as COVID-19. The current study reports the epidemiological and clinical attributes of COVID-19 in Baluchistan. Objective: This study aimed to investigate the epidemiological parameters and route of transmission of COVID-19 positivity that will help the health department develop future strategies to handle deadly pandemics. Methodology: This study was performed by gathering information from patients with their socioeconomics, epidemiological status, history of comorbidity, and clinical signs of the disease. The data was collected from the COVID-19 dashboard. A correlation test was applied to evaluate the connection between clinical pathological parameters. Results: A sum of 3999 clinical records was analyzed. Total 70.8% of patients were positive, and 29.2% were negative. The most affected group was aged 22-42, however, disease severity increased with age. Most positive patients had a high fever, severe cough, sore throat, body ache, shortness of breath and comorbidity on clinical pathological grounds. The earliest reported cases of the infection were connected to travelers returning to Pakistan from Iran. The spread among men was higher as compared to women. Conclusion: This report will display a linkage between the studies of disease transmission and clinical features which thus can be helpful to forestall the local transmission of similar infections in future. The epidemiological literature on this topic from Baluchistan is scarce.
背景:一种病毒性呼吸道疾病的兴起在中国得到了认可,后来被称为COVID-19。本研究报告了俾路支省COVID-19的流行病学和临床特征。目的:了解新型冠状病毒感染的流行病学参数和传播途径,为卫生部门制定未来应对致命流行病的策略提供依据。方法:本研究通过收集患者的社会经济、流行病学状况、合并症史和疾病的临床症状等信息来进行。数据是从COVID-19仪表板收集的。采用相关性检验评价临床病理参数之间的相关性。结果:共分析3999份临床记录。阳性70.8%,阴性29.2%。受影响最大的年龄组是22-42岁,然而,疾病的严重程度随着年龄的增长而增加。多数阳性患者临床病理表现为高热、严重咳嗽、喉咙痛、体痛、气短及合并症。最早报告的感染病例与从伊朗返回巴基斯坦的旅行者有关。与女性相比,男性的感染率更高。结论:本报告将显示疾病传播研究与临床特征之间的联系,从而有助于预防未来类似感染的本地传播。来自俾路支省关于这一主题的流行病学文献很少。
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引用次数: 0
A spectrum of severity and prevalence of malignant hyperthermia in anesthetized patients with inhalational anesthetic. 吸入性麻醉患者恶性高热的严重程度和流行程度。
Pub Date : 2023-07-09 DOI: 10.32593/jstmu/vol6.iss1.232
A. Khan, Muhammad Imran, Amjad Hayat Khan, Yaseen Hussain, Fazlullah Khan
Introduction: Malignant hyperthermia (MH) or hyperpyrexia is a pharmacogenetic syndrome of skeletal muscles caused by volatile anesthetics such as halothane and depolarized muscle relaxant suxamethonium. The prevalence of MH in Islamabad has not been explored. Methodology: This was a retrospective study on the severity and prevalence of MH in anesthetized patients with inhalational anesthetics Clinical data from the previous years, i.e. from June 2020 to June 2021, from eight tertiary care hospitals in Islamabad was collected. Results: Out of 40,900 patients discharged from these hospitals under general anesthesia, only 07 patients were diagnosed with MH due to anesthesia. MH is associated with gender; in our study, more incidence was observed in males than females. Of the seven patients with MH, four (57.14%) were males, and three (42.86%) were females. The prevalence rate of MH was 0.018% due to anesthesia in surgical patients which is approximately 1 per 5842 cases. Conclusion: This research study concluded that the prevalence rate of MH in Islamabad is 0.018%. The prevalence rate for males is slightly higher than for females. According to this statement, the total number of male patients who got MH was four, and females were three out of 40900 surgical cases under general anesthesia in a specific year of duration. The prevalence of MH due to anesthesia in surgical patients treated in Islamabad hospitals is approximately 1 per 5842 cases. MH risk in males is significantly higher than in females.
恶性高热(MH)或高热是由挥发性麻醉剂如氟烷和去极化肌肉松弛剂磺胺甲铵引起的骨骼肌药物遗传综合征。在伊斯兰堡,MH的流行情况尚未得到调查。方法:回顾性研究吸入麻醉剂麻醉患者MH的严重程度和患病率。收集了伊斯兰堡8家三级医院前几年(即2020年6月至2021年6月)的临床数据。结果:在40900例全麻出院患者中,仅有07例因麻醉而诊断为MH。MH与性别有关;在我们的研究中,男性的发病率高于女性。7例MH患者中,男性4例(57.14%),女性3例(42.86%)。手术患者麻醉所致MH患病率为0.018%,约为1 / 5842例。结论:本研究得出伊斯兰堡地区MH患病率为0.018%。男性的患病率略高于女性。根据这一说法,在特定年份的40900例全身麻醉手术中,男性患者总数为4例,女性患者总数为3例。在伊斯兰堡医院接受手术治疗的病人中,因麻醉导致的MH患病率约为1 / 5842。男性的MH风险明显高于女性。
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引用次数: 0
Upholding the responsible conduct of medical research in Pakistan: The buck stops where? 在巴基斯坦坚持负责任的医学研究行为:责任止于何处?
Pub Date : 2023-07-09 DOI: 10.32593/jstmu/vol6.iss1.229
A. Sherin
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引用次数: 0
Hyper Immunoglobulin E (IgE); an immune deficiency (Job Syndrome) 高免疫球蛋白E;免疫缺陷(工作综合症)
Pub Date : 2023-07-09 DOI: 10.32593/jstmu/vol6.iss1.225
S. Ismail, Fatima Khurshid
Hyper-IgE Syndrome (HIES), also known as Job Syndrome; is a rare genetic disorder that affects the immune system and can lead to various health complications. The text mentions cornerstone of HIES therapy is proper skin care, infection prevention, and aggressive infection treatment. Treatments for HIES can include antibiotics that target S. aureus, typically used to reduce the incidence of pneumonia and the risk of lung damage. Skincare routines can involve bleach baths or chlorhexidine washes, oral anti-staphylococcal prophylactic antibiotics, and other treatments to avoid abscesses. Antifungal prophylaxis may be beneficial for HIES patients who have chronic Candida infections. Defects in antibody synthesis can vary, making it difficult to provide general recommendations for immune globulin replacement in HIES.
高ige综合征(HIES),也被称为工作综合征;是一种罕见的遗传性疾病,会影响免疫系统,并导致各种健康并发症。文中提到HIES治疗的基石是适当的皮肤护理,感染预防和积极的感染治疗。HIES的治疗包括针对金黄色葡萄球菌的抗生素,通常用于减少肺炎的发病率和肺损伤的风险。护肤程序包括漂白剂浴或洗氯己定,口服抗葡萄球菌预防性抗生素,以及其他避免脓肿的治疗。抗真菌预防可能对患有慢性念珠菌感染的HIES患者有益。抗体合成缺陷可能各不相同,因此很难提供HIES中免疫球蛋白替代的一般建议。
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引用次数: 0
Effect of seasonal changes on frequency of eclampsia in patients presenting to Ayub Teaching Hospital. 季节变化对Ayub教学医院患者子痫发生频率的影响
Pub Date : 2023-07-09 DOI: 10.32593/jstmu/vol6.iss1.238
Aneesa Fawad, Bushra Zardad, H. Jadoon, A. Ismail
Introduction: Eclampsia is an acute obstetrical emergency carrying high maternal and perinatal morbidity and mortality. High blood pressure during pregnancy after 20 weeks of gestation is associated with proteinuria and generalized tonic-clonic convulsions. The purpose of the study is to observe seasonal variation in the presentation of eclampsia in a tertiary-level hospital. Methods: This is two years study conducted in the Gynae A unit, Ayub teaching hospital, Abbottabad, from January 2021 to December 2022. The study included all the patients admitted to the unit with eclampsia. It included antenatal patients and patients who developed eclampsia in labour or perpurium. Patients with a history of fits due to epilepsy or any other neurological disease were excluded from the study.  Results: The total number of patients admitted with eclampsia during this period was 88 (1.22 %). The majority of patients were in the age group between 21 to 35 years (78.3%). There were 52 primigravidas out of 88(59.1%). There were 46 multigravidas (40.9%). 78 patients out of 88(88.6 %) belonged to areas more than 25 kilometres away from a medical facility. The season was cross-tabulated with different variables, and no statistical significance was found. Conclusion: Eclampsia is a severe obstetrical emergency usually involving young primigravidas with poor socioeconomic status and no antenatal care. Primary prevention is regular antenatal care. Early referral and time management will reduce maternal and perinatal morbidity and mortality. The incidence of eclampsia is more in the fall and winter seasons.
子痫是一种急性产科急诊,具有较高的孕产妇和围产期发病率和死亡率。妊娠20周后的妊娠高血压与蛋白尿和全身性强直阵挛有关。本研究的目的是观察在三级医院子痫表现的季节变化。方法:这是一项为期两年的研究,于2021年1月至2022年12月在阿伯塔巴德Ayub教学医院妇科A部进行。该研究纳入了该部门收治的所有子痫患者。它包括产前患者和在分娩或产后发生子痫的患者。有癫痫或其他神经系统疾病病史的患者被排除在研究之外。结果:本组收治子痫患者88例(1.22%)。大多数患者年龄在21 ~ 35岁之间(78.3%)。88例中有52例为原始性,占59.1%。多胎妊娠46例(40.9%)。88名患者中有78名(88.6%)属于距离医疗设施25公里以上的地区。季节与不同变量交叉表,没有发现统计学意义。结论:子痫是一种严重的产科急症,常见于社会经济状况不佳和产前护理不足的初产妇。初级预防是定期的产前保健。早期转诊和时间管理将降低孕产妇和围产期发病率和死亡率。子痫多发生在秋冬季节。
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引用次数: 0
The cardiovascular system's Renin-Angiotensin-Aldosterone System (RAAS). 心血管系统肾素-血管紧张素-醛固酮系统(RAAS)。
Pub Date : 2023-07-09 DOI: 10.32593/jstmu/vol6.iss1.224
Lamiaa Saoud Abbod, Fatima Amir Abd Algabar
The renin-angiotensin-aldosterone system (RAAS) has a noteworthy part in triggering, and inflammation is maintained by its physiological agents. A crucial mechanism for the initiation and headway of CVD, including Hypertension and atherosclerosis, is inflammation. In addition to its primary function in controlling blood pressure and its contribution to Hypertension, RAAS has pro-inflammatory and profibrotic cellular and molecular effects. Cardiovascular and renal disorders can be treated more effectively by hindering RAAS. Proof recommends that RAAS inhibition enhances vascular remodelling and gets better CVD sequels. Lower levels of oxidative stress and endothelial dysfunction, vascular inflammation, and favourable effects on endothelial progenitor cell regeneration are likely the causes of RAAS inhibition's sound vascular effects.
肾素-血管紧张素-醛固酮系统(RAAS)在触发炎症中起重要作用,炎症是由其生理因子维持的。包括高血压和动脉粥样硬化在内的心血管疾病的发生和发展的关键机制是炎症。除了其控制血压和高血压的主要功能外,RAAS还具有促炎和促纤维化的细胞和分子作用。阻碍RAAS可更有效地治疗心血管和肾脏疾病。证据表明,抑制RAAS可增强血管重构,改善心血管疾病后遗症。较低水平的氧化应激和内皮功能障碍、血管炎症以及对内皮祖细胞再生的有利影响可能是RAAS抑制良好血管效应的原因。
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引用次数: 0
Apprehension among medical students while dealing with patients: A cross-sectional study in a private sector medical college and teaching hospital. 医学生在处理病人时的恐惧:一项在私立医学院和教学医院的横断面研究。
Pub Date : 2023-07-09 DOI: 10.32593/jstmu/vol6.iss1.231
Saad Amir Zaman, Shahroz Zahid, Umer Ijaz, Amna Khan, Ramsha Abbas
Introduction: Beginning to deal with patients can be a testing experience for medical students. Many schools have endeavored to understand students' perceptions and acclimatize them to the stresses of clinical work with success. Objective: This study aimed to identify undergraduate students' apprehensions when dealing with patients, explore the underlying causes of these apprehensions, examine gender differences in apprehension levels, and investigate any effect of patient encounters on career choices. Methodology: This cross-sectional study was conducted on third, fourth and fifth-year medical students of Shifa College of Medicine, selected by simple random sampling. Data was collected using a self-administered questionnaire. Statistical analysis was done using Statistical Package for the Social Sciences (SPSS). Results: Results showed that 22.5% of the students felt significant apprehension when dealing with contagious patients, 11.2% with psychiatric patients, and 13.0% with terminal patients. Male students exhibited more apprehension than female students when interacting with female patients of similar age (p=0.0001) and middle age (p=0.020). Greater apprehension was felt in the Emergency Room (mean 2.66) as compared to in-patient (2.07) and community clinic (1.82). The highest level of apprehension was in the presence of a consultant (51.5% answered either 4 or 5). 128 students (75.7%) believed they would be less apprehensive if they saw more patients. Conclusion: Specific apprehensions among medical students were identified when interacting with different types of patients. Gender differences, clinical settings, and the presence of consultants influenced apprehension levels. Increasing patient exposure was seen as one solution to reduce apprehension.
对医学生来说,开始与病人打交道是一种考验。许多学校都努力了解学生的看法,并成功地使他们适应临床工作的压力。摘要目的:本研究旨在了解大学生在面对病人时的恐惧心理,探讨这些恐惧心理的深层原因,探讨恐惧心理的性别差异,并探讨与病人接触对职业选择的影响。方法:横断面研究采用简单随机抽样的方法,选取什法医学院三、四、五年级医学生为研究对象。数据是通过自我管理的问卷收集的。统计分析使用社会科学统计软件包(SPSS)。结果:22.5%的学生在处理传染病患者时有明显的恐惧,11.2%的学生在处理精神病患者时有明显的恐惧,13.0%的学生在处理绝症患者时有明显的恐惧。与年龄相近的女性患者互动时,男学生比女学生表现出更多的恐惧(p=0.0001)和中年(p=0.020)。与住院病人(2.07)和社区诊所(1.82)相比,急诊室(平均2.66)感到更大的恐惧。有51.5%的学生回答“4”或“5”。128名学生(75.7%)认为,如果他们看到更多的病人,他们的担忧程度就会降低。结论:医学生在与不同类型的病人交往时,有不同的担忧。性别差异、临床环境和咨询师的存在影响恐惧水平。增加患者接触被视为减少恐惧的一种解决方案。
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引用次数: 0
Psychological side effects of radiation therapy on cancer patients. 放射治疗对癌症患者的心理副作用。
Pub Date : 2023-07-09 DOI: 10.32593/jstmu/vol6.iss1.230
Fatima Khurshid, Ans Abdul Razzaq, Hafsa Khurshid
Background: In this study, we investigated the prevalence of anxiety and depression in cancer patients undergoing radiation therapy and identified the factors associated with the multidimensional model, including sociodemographic, clinical, function and well-being, and symptom variables. Methodology: The research was conducted at the Shifa International Hospital Ltd. in Islamabad's radiation oncology clinic from February 2022 to May 2022. Assessments of side effects and the intensity of typical symptoms experienced by cancer patients receiving radiation therapy have been carried out using the MD Anderson Symptom Inventory (MDASI) questionnaire. Version 20.0 of the Statistical Package for the Social Sciences (SPSS) has been used to analyze the data. They were described using categorical statistics using frequency and percentage. Results: The majority of participants were women. During the treatment, patients experienced various psychological reactions, such as nausea, Pain, anxiety, depression, fear, fatigue, disturbed sleep, and shortness of breath. Many patients also reported feeling sad, losing enjoyment of life, and having disturbed relationships with people around them. However, the psychological state of patients improved at the end and after the Intervention. Conclusion: Acute psychological side effects appeared in several patients receiving radiation therapy, such as anxiety, depression, fear, and low self-esteem. Hence, we concluded it has a high incidence. So, radiation therapy patients should receive support and care for their psychological well-being.
背景:在本研究中,我们调查了接受放射治疗的癌症患者的焦虑和抑郁患病率,并确定了与多维模型相关的因素,包括社会人口学、临床、功能和幸福感以及症状变量。方法:研究于2022年2月至2022年5月在伊斯兰堡的Shifa国际医院有限公司的放射肿瘤学诊所进行。使用MD安德森症状调查表(MDASI)对接受放射治疗的癌症患者所经历的副作用和典型症状的强度进行了评估。20.0版的社会科学统计软件包(SPSS)已被用于分析数据。使用频率和百分比进行分类统计。结果:大多数参与者为女性。在治疗过程中,患者出现恶心、疼痛、焦虑、抑郁、恐惧、疲劳、睡眠不安、呼吸短促等心理反应。许多患者还报告说,他们感到悲伤,失去了生活的乐趣,与周围人的关系受到了干扰。然而,在干预结束时和干预后,患者的心理状态有所改善。结论:放疗患者出现焦虑、抑郁、恐惧、自卑等急性心理不良反应。因此,我们得出结论,它的发病率很高。因此,接受放射治疗的患者应该得到心理健康方面的支持和照顾。
{"title":"Psychological side effects of radiation therapy on cancer patients.","authors":"Fatima Khurshid, Ans Abdul Razzaq, Hafsa Khurshid","doi":"10.32593/jstmu/vol6.iss1.230","DOIUrl":"https://doi.org/10.32593/jstmu/vol6.iss1.230","url":null,"abstract":"Background: In this study, we investigated the prevalence of anxiety and depression in cancer patients undergoing radiation therapy and identified the factors associated with the multidimensional model, including sociodemographic, clinical, function and well-being, and symptom variables. \u0000Methodology: The research was conducted at the Shifa International Hospital Ltd. in Islamabad's radiation oncology clinic from February 2022 to May 2022. Assessments of side effects and the intensity of typical symptoms experienced by cancer patients receiving radiation therapy have been carried out using the MD Anderson Symptom Inventory (MDASI) questionnaire. Version 20.0 of the Statistical Package for the Social Sciences (SPSS) has been used to analyze the data. They were described using categorical statistics using frequency and percentage. \u0000Results: The majority of participants were women. During the treatment, patients experienced various psychological reactions, such as nausea, Pain, anxiety, depression, fear, fatigue, disturbed sleep, and shortness of breath. Many patients also reported feeling sad, losing enjoyment of life, and having disturbed relationships with people around them. However, the psychological state of patients improved at the end and after the Intervention. \u0000Conclusion: Acute psychological side effects appeared in several patients receiving radiation therapy, such as anxiety, depression, fear, and low self-esteem. Hence, we concluded it has a high incidence. So, radiation therapy patients should receive support and care for their psychological well-being.","PeriodicalId":302306,"journal":{"name":"Journal of Shifa Tameer-e-Millat University","volume":"14 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130603298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Shifa Tameer-e-Millat University
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