某三级保健中心治疗冠状病毒病相关毛霉病患者的临床流行病学研究

M. Reddy Y
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引用次数: 0

摘要

目的:本研究的主要目的是评估与冠状病毒病相关毛霉病(CAM)相关的临床和流行病学因素,并进一步认识疫苗接种在预防毛霉病进展中的作用。材料与方法:对300例以侵袭性真菌性鼻窦炎症状就诊的冠状病毒病治疗史患者进行回顾性观察研究。对数据进行分析以评估与CAM相关的因素。结果与结论:接种一剂或两剂新冠肺炎疫苗与CAM有一定的统计学意义,但只有少数患者接种了疫苗剂量。其他因素包括年龄、性别、糖尿病(原发性与慢性)、类固醇使用、氧气和瑞德西韦给药均不显著。疫苗接种可能在减少Covid-19的后遗症和死亡率方面发挥关键作用,同时提供针对CAM的保护。
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A Clinical Epidemiological Study of Patients with Coronavirus Disease Associated Mucormycosis Treated at A Tertiary Care Nodal Centre
Objective: The main objective of this study was to assess clinical and epidemiological factors associated with coronavirus disease associated mucormycosis (CAM) and furthermore to recognize the role of vaccination in preventing the progression of mucormycosis. Materials and methods: A retrospective observational study was conducted on 300 patients with past history of being treat-ed for coronavirus disease and who presented to our department with symptoms of invasive fungal sinusitis. The data were analyzed to assess the factors associated with CAM. Results and Conclusion: Receiving COVID-19 vaccination either one or two doses had some statistically significant associa-tion with CAM, however, only a small number of patients received vaccination doses. Other factors including age, gender, dia-betes (denovo vs. chronic), steroid use, oxygen, and remdesivir administration were not significant. Vaccination may play a key role in lessening the sequelae and mortality due to Covid-19 while providing protection against CAM.
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