一种用于帕金森病患者听觉提示步态分析的可穿戴装置

Alessandra Pacilli, Ilaria Mileti, M. Germanotta, E. D. Sipio, Isabella Imbimbo, I. Aprile, L. Padua, S. Rossi, E. Palermo, P. Cappa
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引用次数: 13

摘要

步态障碍是帕金森病(PD)的主要后果,导致患者丧失独立性。近年来,节律听觉刺激(rhythm Auditory Stimulation, RAS)对步态质量的改善给出了初步的证明,但具体的方法需要较长的步道,传统的完整的步态分析无法使用。在目前的工作中,我们描述了一种不显眼的、可穿戴的装置和相关的生物力学模型,用于分析帕金森病患者在RAS管理期间的步态。一名健康受试者被纳入实验阶段,以验证由光电系统提供的空间步态参数的估计。然后招募了三名PD患者,以测试该设置在评估此类研究中通常采用的步态参数方面的可行性。空间参数估计的验证结果表明,该系统对步幅的估计精度较高。对帕金森病患者的初步测试为可穿戴设备的可用性和多功能性提供了令人鼓舞的见解。未来将在更大的人群中进行实验验证,以充分验证该设置,这为在实验室环境之外进行RAS研究开辟了道路。
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A wearable setup for auditory cued gait analysis in patients with Parkinson's Disease
Gait disorders are a primary consequence of Parkinson's Disease (PD), resulting in loss of patients' independence. Recently, Rhythmical Auditory Stimulation (RAS) gave a preliminary proof to benefit gait quality, but the specific methodology requires a long walkway, preventing the use of a traditional complete gait analysis. In the present work we describe an unobtrusive, wearable setup and the related biomechanical model developed for analyzing gait of people with PD during the administration of RAS. One healthy subject was enrolled in the experimental session to validate the estimation of the spatial gait parameters provided by the proposed setup, against an optoelectronic system. Three PD patients were then enrolled to test the setup feasibility in evaluating gait parameters typically adopted in these type of studies. Results related to the validation of the spatial parameter estimation showed a high accuracy of the system in the estimation of the stride length. Preliminary tests on PD patients provided encouraging insights on the wearable setup usability and versatility. Future experimental validation on a larger population will be conducted to fully validate the setup, which opens the way for conducting RAS studies also outside the laboratory environment.
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