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2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)最新文献

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Classification of cognitive and resting states of the brain using EEG features 利用脑电图特征对大脑的认知和静息状态进行分类
Pub Date : 2016-08-08 DOI: 10.1109/MeMeA.2016.7533741
Rana Fayyaz Ahmad, A. Malik, H. Amin, N. Kamel, F. Reza
Human brain is considered as complex system having different mental states e.g., rest, active or cognitive states. It is well understood fact that brain activity increases with the cognitive load. This paper describes the cognitive and resting state classification based on EEG features. Previously, most of the studies used linear features. EEG signals are non-stationary in nature and have complex dynamics which is not fully mapped by linear methods. Here, we used non-linear feature extraction methods to classify the cognitive and resting states of the human brain. Data acquisition were carried out on eight healthy participants during cognitive state i.e., IQ task and rest conditions i.e., eyes open. After preprocessing, EEG features were extracted using both linear as well as non-linear. Further, these features were passed to the classifier. Results showed that with support vector machine (SVM), we achieved 87.5% classification accuracy with linear and 92.1% classification accuracy with non-linear features.
人脑被认为是一个复杂的系统,具有不同的精神状态,如休息状态、活动状态和认知状态。众所周知,大脑活动随着认知负荷的增加而增加。本文描述了基于脑电特征的认知状态和静息状态分类。以前,大多数研究使用线性特征。脑电图信号本质上是非平稳的,具有复杂的动态特性,不能用线性方法完全映射。在这里,我们使用非线性特征提取方法对人脑的认知状态和静息状态进行分类。对8名健康受试者在认知状态(即智商任务)和休息状态(即睁眼)下进行数据采集。预处理后的脑电信号特征提取采用线性和非线性两种方法。此外,这些特征被传递给分类器。结果表明,使用支持向量机(SVM)对线性特征的分类准确率为87.5%,对非线性特征的分类准确率为92.1%。
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引用次数: 17
Investigation of temperature rise in tissue — Mimicking material induced by a HIFU transducer HIFU换能器诱导组织模拟材料温升的研究
Pub Date : 2016-08-08 DOI: 10.1109/MeMeA.2016.7533737
B. Karaboce, Emel Çetin, H. Durmuş
In this study, temperature distribution inside a tissue - mimicking material induced by a HIFU (High Intensity Focused Ultrasound) transducer was investigated with two different methods. In first method T-type thermocouple (TC) temperature sensors and in second method, infrared (IR) camera system was used for determining the temperature distribution on the tissue-mimicking material (TMM). Temperature increase and distribution in the TMM have been characterized during the ultrasonic power application. Temperature measurements were actualized inside a TMM which has characteristics very similar to human liver tissue. Temperature rise has been characterized for different input ultrasonic powers and durations. Two different temperature measuring tools were compared and consistency between these methods was presented.
在本研究中,用两种不同的方法研究了高强度聚焦超声换能器诱导的组织模拟材料内部的温度分布。第一种方法采用t型热电偶温度传感器,第二种方法采用红外摄像系统测定模拟组织材料(TMM)的温度分布。研究了超声功率应用过程中TMM内的温升和温度分布。温度测量在TMM内实现,TMM具有与人类肝组织非常相似的特征。在不同的超声输入功率和持续时间下,温度升高具有特征。比较了两种不同的测温工具,并给出了它们之间的一致性。
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引用次数: 14
Influence of fiber Bragg grating length on temperature measurements in laser-irradiated organs 光纤光栅长度对激光辐照器官温度测量的影响
Pub Date : 2016-08-08 DOI: 10.1109/MeMeA.2016.7533807
Sara Pangaro, P. Saccomandi, C. Massaroni, S. Silvestri, E. Schena, G. Costamagna, Francesco Maria Di Matteo, M. Caponero, A. Polimadei
The present study investigates the influence of uniform FBG length on temperature measurement under substantial temperature gradient. This analysis is particularly relevant in the scenario of laser ablation (LA), where the temperature gradient close to the optical applicator is significant (e.g., up to 50 °C/mm). Aiming to assess how the sensor length affects the measurement process in LA, both bench and ex vivo experiments were carried out by applying temperature gradient in the range 5 °C/cm-30 °C/cm on 1 mm-length FBG and 10 mm-length FBG. Results showed that the use of small-sized FBGs is recommended in LA for two main reasons: i) the spectrum reflected by shorter sensors has not shown significant alterations with the gradient. Alterations of the spectrum shape could compromise peak detection algorithms, and, therefore, the estimation of the actual temperature; ii) Arrays of shorter sensors can provide multipoint temperature measurements, with quiet good spatial resolution (e.g., 3 mm), by inserting a single fiber in the tissue.
本文研究了在温度梯度较大的情况下,均匀光纤光栅长度对温度测量的影响。这种分析在激光烧蚀(LA)的情况下特别相关,其中靠近光学涂敷器的温度梯度是显著的(例如,高达50°C/mm)。为了评估传感器长度对LA测量过程的影响,对长度为1 mm和10 mm的光纤光栅施加5°C/cm-30°C/cm范围内的温度梯度,进行了实验和离体实验。结果表明,在LA中推荐使用小型fbg主要有两个原因:1)较短传感器反射的光谱随梯度变化不明显;光谱形状的改变可能会影响峰检测算法,从而影响对实际温度的估计;ii)通过在组织中插入一根纤维,较短的传感器阵列可以提供多点温度测量,具有非常好的空间分辨率(例如3毫米)。
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引用次数: 2
Preliminary study of a robotic rehabilitation system driven by EMG for hand mirroring 手镜肌电驱动机器人康复系统的初步研究
Pub Date : 2016-08-08 DOI: 10.1109/MEMEA.2016.7533730
M. Serpelloni, M. Tiboni, M. Lancini, S. Pasinetti, A. Vertuan, M. Gobbo
Robotic devices can be a viable solution in different rehabilitation activities for increasing patients' gains, providing high-frequent, repetitive and interactive rehabilitation treatments. In this paper, the design, development and preliminary characterization of a robotic system for assisted hand rehabilitation, driven by surface EMG measurements, based on the mirroring of healthy hand movements is presented. The healthy hand opening and closing is detected by the muscular activity and this is used to guide a robotic glove moving the paretic hand. The innovative aspects of the research deal firstly in the contemporaneous use of EMG signals and mirroring technique and secondly in the development of an algorithm for the automatic setting of the actuators thresholds. A preliminary system characterization was conducted. The performed tests demonstrate that the system is a viable solution to allow a healthy person to perform exercises of “hand closing” “hand opening”, with ON-OFF and proportional controls, with a success rate in tests carried out by 98%. The proposed system is a starting point for a novel approach to hand mirroring rehabilitation on patients with upper-limb motor deficits.
机器人设备可以在不同的康复活动中为增加患者的收益提供一个可行的解决方案,提供高频率,重复和互动的康复治疗。本文介绍了一种基于健康手部运动镜像,由表面肌电测量驱动的辅助手部康复机器人系统的设计、开发和初步表征。健康手的张开和闭合是通过肌肉活动来检测的,这是用来指导机器人手套移动麻痹的手。这项研究的创新之处首先在于同时使用肌电信号和镜像技术,其次在于开发一种自动设置执行器阈值的算法。对系统进行了初步表征。测试结果表明,该系统是一种可行的解决方案,可以让健康人进行“合手”和“开手”的练习,具有开关和比例控制,测试成功率为98%。该系统是上肢运动障碍患者手部镜像康复新方法的起点。
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引用次数: 13
Optimal peripheral measurement point for the assessment of preterm patients in intensive care units 重症监护病房早产儿评估的最佳周边测量点
Pub Date : 2016-08-08 DOI: 10.1109/MeMeA.2016.7533817
I. Ercoli, L. Scalise, P. Marchionni, E. P. Tomasini, V. Carnielli
In neonatal intensive care units many important vital signs are continuously measured in order to have a full monitoring of the patient. To this aim, cardiac rate, respiration activity, blood saturation, body temperature are extensively collected by contact sensors. Temperature, particularly in preterm infants, is a key quantity to be assessed if the aim is to verify the patient development and is/her capacity to regulate the body temperature. Presently, hospital cribs are equipped with large resistance thermometers (two or more); one for measuring temperature at the hepatic site and the second to assess temperature from peripheral sites (i.e. arms, legs). The aim of this paper is to identify the optimal measurement point for the assessment of the skin temperature in peripheral sites. The experimental procedure utilized is based on the use of a multi-point (6 sensing points) measurement system of the skin temperature and of the crib environmental temperature. In this study, 50 premature patients (mean gestation age 34 weeks and mean weight 1791 g) have been measured. Results demonstrate that from the measured data, it is possible to correctly identify the left hand as the measurement point presenting the smallest differences (<; 1.04°C), respect to the central body temperature values (measured in correspondence to the liver).
在新生儿重症监护病房,为了对患者进行全面监测,需要连续测量许多重要的生命体征。为此,通过接触式传感器广泛收集心率、呼吸活动、血饱和度、体温。如果目的是验证患者的发育和他/她调节体温的能力,那么体温,特别是早产儿的体温,是一个需要评估的关键指标。目前,医院的婴儿床配备了大电阻温度计(两个或更多);一个用于测量肝脏部位的温度,第二个用于评估周围部位(即手臂,腿)的温度。本文的目的是确定最佳的测量点,以评估皮肤温度在周围的网站。所使用的实验程序是基于使用多点(6个感测点)测量皮肤温度和婴儿床环境温度的系统。本研究测量了50例早产儿(平均胎龄34周,平均体重1791 g)。结果表明,从测量数据中,可以正确识别出左手作为呈现最小差异的测量点(<;1.04°C),相对于中心体温值(与肝脏对应测量)。
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引用次数: 0
Scoring systems in dermatology 皮肤病评分系统
Pub Date : 2016-08-08 DOI: 10.1109/MeMeA.2016.7533793
G. Cevenini, S. Furini, P. Barbini, L. Tognetti, P. Rubegni
Three scoring systems were considered and described for dermatological applications in which malignant and benign skin lesions have to be recognized: two models are derived from logistic regression and naïve Bayes rule by rounding model parameters to their nearest integer values; the third approach defines the scoring system by a direct stepwise adding of the most significant binary risk factors. An application example of a direct score model was then developed to illustrate important aspects of its design in dermoscopy. The results show that, having many variables available, score models combine simplicity, practicality, high accuracy and good control of overfitting. Also they can incorporate different diagnostic styles of experienced dermatologists, introducing into the model subjective binary variables, some of which also assessed with a significant degree of disagreement.
对于必须识别恶性和良性皮肤病变的皮肤病学应用,考虑并描述了三种评分系统:通过将模型参数舍入到最接近的整数值,从逻辑回归和naïve贝叶斯规则推导出两个模型;第三种方法通过直接逐步添加最显著的二元风险因素来定义评分系统。然后开发了一个直接评分模型的应用示例,以说明其在皮肤镜检查中的设计的重要方面。结果表明,分数模型具有变量多的特点,具有简单、实用、精度高、控制过拟合的特点。此外,他们还可以结合经验丰富的皮肤科医生的不同诊断风格,将主观二元变量引入模型,其中一些变量的评估也存在很大程度的分歧。
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引用次数: 58
Preliminary results of a low-cost 4-channel time-correlated single photon counting system for time-domain diffuse optical tomography 用于时域漫射光学层析成像的低成本四通道时间相关单光子计数系统的初步结果
Pub Date : 2016-08-08 DOI: 10.1109/MeMeA.2016.7533733
J. Bouchard, W. Lemaire, Arnaud Samson, C. Paulin, J. Pratte, Y. B. Lauzière, R. Fontaine
Time-domain diffuse optical tomography (TD-DOT) provides information-rich data that have not yet been fully exploited for image reconstruction, notably to increase imaging spatial resolution. Current TD-DOT scanners suffer from a very low sensitivity owing to their small number of detection channels. This leads to excessively long acquisition times for in vivo imaging. To obtain a higher number of detection channels, thus increasing detection density, a low-cost time-correlated single photon counting (TCSPC) system dedicated to TD-DOT imaging was designed and developed, resorting solely to off-the-shelf electronic components to reduce costs, in distinction to custom application-specific integrated circuit (ASIC) solutions. It features 4 input channels with a 13.02 ps bin width and a 18.1 ps FWHM accuracy throughout a measurement dynamic range of 12.5 ns. Each channel includes a leading-edge discriminator, with a programmable threshold, for direct interfacing with off-the-shelf photodetector modules. A software-programmable delay line was added to the channel signal path to compensate for undesired propagation delays. The system also supports a virtually unlimited number of TCSPC channels using a daisy-chain configuration through an onboard Ethernet switch.
时域漫射光学层析成像(TD-DOT)提供了信息丰富的数据,尚未完全用于图像重建,特别是提高成像空间分辨率。目前的TD-DOT扫描仪由于检测通道数量少,灵敏度很低。这导致体内成像的采集时间过长。为了获得更多的检测通道,从而增加检测密度,设计和开发了一种专门用于TD-DOT成像的低成本时间相关单光子计数(TCSPC)系统,完全依靠现成的电子元件来降低成本,而不是定制的专用集成电路(ASIC)解决方案。它具有4个输入通道,在12.5 ns的测量动态范围内具有13.02 ps的bin宽度和18.1 ps的FWHM精度。每个通道包括一个具有可编程阈值的前沿鉴别器,用于与现成的光电探测器模块直接接口。在信道信号路径中增加了一条软件可编程延迟线,以补偿不希望的传播延迟。该系统还支持几乎无限数量的TCSPC通道,通过板载以太网交换机使用菊花链配置。
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引用次数: 1
A wearable setup for auditory cued gait analysis in patients with Parkinson's Disease 一种用于帕金森病患者听觉提示步态分析的可穿戴装置
Pub Date : 2016-08-04 DOI: 10.1109/MeMeA.2016.7533796
Alessandra Pacilli, Ilaria Mileti, M. Germanotta, E. D. Sipio, Isabella Imbimbo, I. Aprile, L. Padua, S. Rossi, E. Palermo, P. Cappa
Gait disorders are a primary consequence of Parkinson's Disease (PD), resulting in loss of patients' independence. Recently, Rhythmical Auditory Stimulation (RAS) gave a preliminary proof to benefit gait quality, but the specific methodology requires a long walkway, preventing the use of a traditional complete gait analysis. In the present work we describe an unobtrusive, wearable setup and the related biomechanical model developed for analyzing gait of people with PD during the administration of RAS. One healthy subject was enrolled in the experimental session to validate the estimation of the spatial gait parameters provided by the proposed setup, against an optoelectronic system. Three PD patients were then enrolled to test the setup feasibility in evaluating gait parameters typically adopted in these type of studies. Results related to the validation of the spatial parameter estimation showed a high accuracy of the system in the estimation of the stride length. Preliminary tests on PD patients provided encouraging insights on the wearable setup usability and versatility. Future experimental validation on a larger population will be conducted to fully validate the setup, which opens the way for conducting RAS studies also outside the laboratory environment.
步态障碍是帕金森病(PD)的主要后果,导致患者丧失独立性。近年来,节律听觉刺激(rhythm Auditory Stimulation, RAS)对步态质量的改善给出了初步的证明,但具体的方法需要较长的步道,传统的完整的步态分析无法使用。在目前的工作中,我们描述了一种不显眼的、可穿戴的装置和相关的生物力学模型,用于分析帕金森病患者在RAS管理期间的步态。一名健康受试者被纳入实验阶段,以验证由光电系统提供的空间步态参数的估计。然后招募了三名PD患者,以测试该设置在评估此类研究中通常采用的步态参数方面的可行性。空间参数估计的验证结果表明,该系统对步幅的估计精度较高。对帕金森病患者的初步测试为可穿戴设备的可用性和多功能性提供了令人鼓舞的见解。未来将在更大的人群中进行实验验证,以充分验证该设置,这为在实验室环境之外进行RAS研究开辟了道路。
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引用次数: 13
Feasibility assessment of an FBG-based probe for distributed temperature measurements during laser ablation 基于fbg的激光烧蚀分布式温度测量探头的可行性评估
Pub Date : 2016-05-15 DOI: 10.1109/MeMeA.2016.7533805
N. Santo, Camilla Cavaiola, P. Saccomandi, C. Massaroni, F. Giurazza, G. Frauenfelder, E. Schena, Francesco Maria Di Matteo, G. Costamagna, M. Caponero, A. Polimadei
During thermal procedures, the monitoring of tissue temperature is useful to improve therapy success. The aim of this study is the feasibility assessment of a Fiber Bragg Grating (FBG)-based probe, which contains six FBGs, to obtain distributed temperature measurement in tissue undergoing laser ablation (LA). Among different thermometric techniques, FBG sensors show valuable characteristics, even though their sensitivity to strain entails measurement error for patient respiratory movement. We performed: i) the static calibration of the FBG-based probe to estimate the thermal sensitivity of the six FBGs; ii) the estimation of the response time of the FBGs. All FBGs have a thermal sensitivity of 10 pm·°C-1 and a time constant in the order of <; 250 ms. Additionally, we performed a preliminary estimation of the error due to the strain and caused by respiratory movements. Experiments were carried out by simulating a typical respiratory movement on ex vivo swine liver. The measurement error was <;0.6 °C for all FBGs. Eventually, experiments were performed on ex vivo porcine liver undergoing LA to assess the measurement error, called artifact, caused by the direct absorption of the laser light by the metallic needle. The artifact was firstly investigated at 12 relative positions between the needle and the laser applicator, then corrected by a two-variables model. After adjustment, the artifact decreases from about 2.1 °C to about 0.1 °C. The solutions proposed in this study foster confirming the feasibility of the FBG-based probe for temperature monitoring in organ undergoing LA.
在热过程中,组织温度的监测有助于提高治疗成功率。本研究的目的是评估基于光纤布拉格光栅(FBG)的探针的可行性,该探针包含6个光纤光栅,用于在激光烧蚀(LA)组织中获得分布式温度测量。在不同的温度测量技术中,FBG传感器显示出有价值的特性,尽管它们对应变的敏感性会导致患者呼吸运动的测量误差。我们进行了:i)基于fbg的探针的静态校准,以估计6种fbg的热敏度;ii) fbg响应时间的估计。所有fbg的热敏度均为10 pm·°C-1,时间常数为<;250 ms。此外,我们进行了初步估计由于应变和呼吸运动引起的误差。在离体猪肝上模拟典型的呼吸运动进行了实验。所有fbg的测量误差均< 0.6°C。最后,在离体猪肝上进行实验,以评估金属针直接吸收激光引起的测量误差,即伪影。首先在针和激光涂抹器之间的12个相对位置研究了伪影,然后通过双变量模型进行了校正。调整后,伪影从约2.1°C降低到约0.1°C。本研究提出的解决方案进一步证实了基于fbg的探针在接受LA的器官中进行温度监测的可行性。
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引用次数: 8
Low-power wireless system for temperature and humidity monitoring in artificial ventilation 用于人工通风中温湿度监测的低功耗无线系统
Pub Date : 2016-05-15 DOI: 10.1109/MEMEA.2016.7533801
A. Bodini, M. Serpelloni, E. Sardini, N. Latronico, M. Tommasi, Matteo Filippini
Artificial ventilators are commonly used with Passive Heat-Moisture Exchangers (HME) to warm and humidify the inspired air in order to ensure a proper conditioning of inspired gases to the artificially ventilated patients. However, different aspects potentially affect their performances and this change in performance should be analyzed in-vivo during HME operation. In this paper, a wireless measurement system is proposed for the monitoring of air temperature and humidity in-vivo. The system is composed by a measuring device connected to the ventilating tube near the HME and a reading device connected to a Personal Computer (PC). Each device integrates a wireless transmission via low-power Bluetooth module that allows limiting power consumption. For the measuring device, the calculated power consumption when all the on-board components are working is about 15 mA, permitting a continuous monitoring for about 5 days and 16 hours with a rechargeable Li-Ion battery of 2050 mAh. A first prototype was manufactured and tested in the laboratory. Then, this prototype was tested with a setup specially developed to simulate human breath. The tests were conduced changing the respiratory rate and minute volume. Preliminary results are reported showing interesting aspects, such as the warm-up time of the HME. Furthermore, the results shows a direct dependence of humidity loss on frequency-volume ratio requiring future investigations. Clinicians are expected to use this system in-vivo to identify the correlations between clinical issues and HME performances.
人工呼吸机通常与被动式热湿交换器(HME)一起使用,以加热和加湿吸入空气,以确保人工通气患者的吸入气体得到适当的调节。然而,不同的方面可能会影响它们的性能,这种性能变化应该在HME手术期间进行体内分析。本文提出了一种用于体内空气温度和湿度监测的无线测量系统。该系统由连接到HME附近通风管的测量装置和连接到个人计算机(PC)的读取装置组成。每个设备通过低功耗蓝牙模块集成了无线传输,从而限制了功耗。对于测量设备,当所有机载组件工作时,计算出的功耗约为15毫安,允许使用2050毫安的可充电锂离子电池连续监测约5天16小时。第一个原型被制造出来并在实验室进行了测试。然后,这个原型用一种专门模拟人类呼吸的装置进行了测试。试验是通过改变呼吸频率和分气量来进行的。报告的初步结果显示了有趣的方面,如HME的预热时间。此外,结果表明湿度损失直接依赖于频率-体积比,需要进一步的研究。临床医生有望在体内使用该系统来确定临床问题与HME表现之间的相关性。
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引用次数: 3
期刊
2016 IEEE International Symposium on Medical Measurements and Applications (MeMeA)
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