混浊介质中的光传播:在生物组织中的应用

F. Fanjul-Vélez, J. L. Arce-Diego
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引用次数: 7

摘要

光通过介质传播的分析是各种应用的基础,包括非制导或基于光纤的制导光通信,工业光学切割或焊接以及生物医学光学。这些应用有时采用异质浑浊介质,如海水、大气或生物组织。浑浊介质具有较强的吸收和散射特性。因此,光在浑浊介质中的传播是一个复杂而具有挑战性的问题。这在生物组织的光学治疗和诊断中尤为重要。在这项工作中,我们描述了混浊介质中光传播演算的不同方法。首先考虑光-物质一般相互作用。混浊介质是用基本光学性质来描述的。由于散射的复杂性,我们特别关注它。生物组织分类和最相关的形态学和光学特征进行了描述。提出了几种光传播模型,应用于最常见的生物组织,并进行了比较。该结果对于安全光学治疗的充分规划至关重要,其中不会产生附带损害,并且对于获得病理的高分辨率图像以便提供早期诊断。
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Light propagation in turbid media: Application to biological tissues
The analysis of the propagation of light through media is fundamental for a great variety of applications, including non-guided or fiber-based guided optical communications, industrial optical cutting or welding, and biomedical optics. These applications employ sometimes heterogeneous turbid media, such as ocean water, the atmosphere or biological tissues. Turbid media present both strong absorption and scattering. As a consequence light propagation in turbid media is a complex and challenging problem. This is specially relevant in optical treatment and diagnosis of biological tissues. In this work, we describe different approaches to the calculus of light propagation in turbid media. Light-matter general interaction is first considered. Turbid media are described by means of fundamental optical properties. Special attention is paid to scattering due to its complexity. Biological tissues are classified and the most relevant morphological and optical characteristics are described. Several light propagation models are proposed, applied to the most common biological tissues, and compared. The results are essential for an adequate planning of safe optical treatments, in which no collateral damage is produced, and for obtaining high-resolution images of pathologies in order to provide an early diagnosis.
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