一种确定COVID-19和普通流感等传染性病毒趋同(或差异)的创新比较研究方法

Lam Kai Shun
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引用次数: 0

摘要

传染病与人类有着悠久的历史。这些疾病从春季的普通流感到最近的COVID-19等都是众所周知的。人们总是希望找到一种治疗方法,比如疫苗。然而,由于这些疾病的病毒在其DNA或RNA中有数千或数百万个突变,因此很难预测来年可能在人群中传播的下一个流行物种。在数学上,组合加优化技术可能是解决问题的最可行的方法。在本论文中,作者提出了一种创新的比较研究方法,包括研究组(HKLam回归)和对照组(其他回归)对COVID-19或普通流感等感染病毒。上述方法用于确定这些病毒的趋同(或)分化突变,以便我们可以进一步对它们进行基因编辑,以获得几个可行的候选疫苗,以便在人类等中进一步研究。换句话说,我们正试图人为地为这些受感染的病毒开发一种量身定制的“牛痘”,从而可能挽救数百万人的生命。
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An Innovate Comparative Research Method to determine the convergence (/or divergence) of the Infective Virus like COVID-19 & Common Flu
Infectious disease has a long history with our human beings. These diseases have been well known from the common flu in Spring to the most recent one such as the COVID-19 etc. People always want to find a cure such as vaccine to them. However, as the diseases’ viruses have thousands or mil-lions of mutation in their DNA or RNA, it is therefore difficult to predict the next popular species that may be spread among people in the coming year. Mathematically, the combinatoric plus the optimi-zation techniques may be the most feasible way to solve the problem. In the present thesis, this author suggests an innovate comparative research method that includes research group (HKLam regres-sion) and the control group (other regressions) to the infected virus such as COVID-19 or common flu etc. The aforementioned method is used to determine these virus(es)’s convergence (/or) diver-gence mutations such that we may further genetic edit them to obtain several feasible vaccine candi-dates for further investigation in human beings etc. In other words, we are trying to artificially devel-oped a tailor made “cow-pox” for these infected viruses and hence may be save millions of our lives.
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