Development of the human mandible under the influence of the environment and/or genetics

Researchers conduct their studies of the mandible by placing it in the “exploitable” framework of systemic biology. They investigate an anomaly of its development, promandibulia, or mandibular prognathism, within this context, by studying molecular and cellular reactions at the level of their constitutive elements and their integration during the course of mandibular development. Here we propose a new etiological and therapeutic approach for this malformation.