心肌梗死发生频率与ABO血型系统的关系

Mohammad Fatteh Ul Islam, Tanzila Rawnuck, Shahanaj Parveen, F. Sonia, N. Akter, Iffat Ara Akber
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引用次数: 0

摘要

背景:ABO血型具有血细胞表面蛋白和内皮细胞相关的血管性血友病因子,有证据表明个体的血型可以提前决定血栓形成的风险。由于冠状动脉疾病的重要性和高患病率,心肌梗死与ABO血型之间的关联尚未得到证实,甚至存在争议。结果。目的:探讨ABO血型与急性心肌梗死的关系。材料和方法:这是一项横断面描述性研究,在达卡Bangabandhu Sheikh Mujib医科大学输血医学系进行。以384例有梗死史的患者为样本。数据的选取采用目的性抽样。使用SPSS-22对收集到的数据进行整理和分析。结果:年龄25 ~ 73岁,平均54.34±17.26岁。大多数患者,182例(47.4%)在45-65岁年龄组。男性295例(76.8%),女性89例(23.2%);男女比例接近3:1。男性和女性STEMI和NSTEMI患者的血型相关性无统计学意义(p>0.05)。然而,与所有其他ABO血型相比,O型血的心肌梗死患病率与NSTEMI和STEMI患者的相关性更为显著。结论:本研究显示了ABO血型与心肌梗死之间的关系,其中O型患者更易发生STEMI和NSTEMI。泰姬酒店2022;35: No-2: 125-131
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Frequency of Myocardial Infarction with the Frame of ABO Blood Group System
Background: The ABO blood group exhibits a blood cell surface protein and an endothelial cell-associated Willebrand factor, and there is evidence that the blood type of individuals can determine the risk of thrombosis in advance. Due to the importance and high prevalence of coronary artery disease, the association between myocardial infarction and ABO blood groups has not been proven, and there are even controversial. Results.  Aims: To determine the relationship between the ABO blood group and acute myocardial infarction. Materials and Methods: It was a cross-sectional descriptive study carried out at the department of Transfusion Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka. A total of 384 patients with a history of infarction as the sample. Purposive sampling was applied for the selection of data. The collected data were organized and analyzed using SPSS-22. Results: Mean age was 54.34±17.26 years, from 25-73 years. Most of the patients, 182 (47.4%) within the 45-65 age group. More than one-third of patients, 295 (76.8%), were male, and 89 (23.2%) patients were female; the male: female ratio was near about 3:1. The association of blood group between STEMI and NSTEMI patients in males and females patients was not statistically significant (p>0.05). However, the prevalence of MI in blood group O is more significantly associated with NSTEMI and STEMI patients than in all other ABO blood groups. Conclusion: The study shows the relation between the ABO blood group and MI, where patients with the O group are more prone to STEMI and NSTEMI. TAJ 2022; 35: No-2: 125-131
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