基于机器学习方法的肿瘤基因组图谱多形性胶质母细胞瘤(TCGA-GBM)分类

Rabia Emhamed Al Mamlook, Ahmad Nasayreh, Hasan Gharaibeh, Sujeet Shrestha
{"title":"基于机器学习方法的肿瘤基因组图谱多形性胶质母细胞瘤(TCGA-GBM)分类","authors":"Rabia Emhamed Al Mamlook, Ahmad Nasayreh, Hasan Gharaibeh, Sujeet Shrestha","doi":"10.1109/eIT57321.2023.10187283","DOIUrl":null,"url":null,"abstract":"Glioblastoma multiforme (GBM) is a highly ma-lignant type of brain cancer with a bleak prognosis. This study aimed to apply machine learning methods to classify GBM samples from the Cancer Genome Atlas (TCGA) dataset. Several supervised learning algorithms, including Support Vector Machine, Ad boost, Neural Network, and Decision Tree, were employed in the analysis. Our findings indicate that the Decision Tree algorithm was the most effective for this classification task, achieving an impressive 99% accuracy. Our study provides evidence that machine learning can accurately classify GBM samples in large-scale genomic datasets, enabling a deeper understanding of the genomic characteristics of this cancer. This study emphasizes the potential of machine learning approaches for improved cancer diagnosis and treatment through the analysis of large-scale genomic datasets.","PeriodicalId":113717,"journal":{"name":"2023 IEEE International Conference on Electro Information Technology (eIT)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"Classification Of Cancer Genome Atlas Glioblastoma Multiform (TCGA-GBM) Using Machine Learning Method\",\"authors\":\"Rabia Emhamed Al Mamlook, Ahmad Nasayreh, Hasan Gharaibeh, Sujeet Shrestha\",\"doi\":\"10.1109/eIT57321.2023.10187283\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Glioblastoma multiforme (GBM) is a highly ma-lignant type of brain cancer with a bleak prognosis. This study aimed to apply machine learning methods to classify GBM samples from the Cancer Genome Atlas (TCGA) dataset. Several supervised learning algorithms, including Support Vector Machine, Ad boost, Neural Network, and Decision Tree, were employed in the analysis. Our findings indicate that the Decision Tree algorithm was the most effective for this classification task, achieving an impressive 99% accuracy. Our study provides evidence that machine learning can accurately classify GBM samples in large-scale genomic datasets, enabling a deeper understanding of the genomic characteristics of this cancer. This study emphasizes the potential of machine learning approaches for improved cancer diagnosis and treatment through the analysis of large-scale genomic datasets.\",\"PeriodicalId\":113717,\"journal\":{\"name\":\"2023 IEEE International Conference on Electro Information Technology (eIT)\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-05-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2023 IEEE International Conference on Electro Information Technology (eIT)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/eIT57321.2023.10187283\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2023 IEEE International Conference on Electro Information Technology (eIT)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/eIT57321.2023.10187283","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

摘要

多形性胶质母细胞瘤(GBM)是一种高度恶性的脑癌,预后黯淡。本研究旨在应用机器学习方法对来自癌症基因组图谱(TCGA)数据集的GBM样本进行分类。在分析中使用了几种监督学习算法,包括支持向量机、Ad boost、神经网络和决策树。我们的研究结果表明,决策树算法对于这个分类任务是最有效的,达到了令人印象深刻的99%的准确率。我们的研究提供了证据,证明机器学习可以在大规模基因组数据集中准确地分类GBM样本,从而能够更深入地了解这种癌症的基因组特征。这项研究强调了通过分析大规模基因组数据集来改善癌症诊断和治疗的机器学习方法的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Classification Of Cancer Genome Atlas Glioblastoma Multiform (TCGA-GBM) Using Machine Learning Method
Glioblastoma multiforme (GBM) is a highly ma-lignant type of brain cancer with a bleak prognosis. This study aimed to apply machine learning methods to classify GBM samples from the Cancer Genome Atlas (TCGA) dataset. Several supervised learning algorithms, including Support Vector Machine, Ad boost, Neural Network, and Decision Tree, were employed in the analysis. Our findings indicate that the Decision Tree algorithm was the most effective for this classification task, achieving an impressive 99% accuracy. Our study provides evidence that machine learning can accurately classify GBM samples in large-scale genomic datasets, enabling a deeper understanding of the genomic characteristics of this cancer. This study emphasizes the potential of machine learning approaches for improved cancer diagnosis and treatment through the analysis of large-scale genomic datasets.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Correlation of Egg counts, Micro-nutrients, and NDVI Distribution for Accurate Tracking of SCN Population Density Detection Supervised Deep Learning Models for Detecting GPS Spoofing Attacks on Unmanned Aerial Vehicles ChatGPT: A Threat Against the CIA Triad of Cyber Security Smart UX-design for Rescue Operations Wearable - A Knowledge Graph Informed Visualization Approach for Information Retrieval in Emergency Situations Comparative Study of Deep Learning LSTM and 1D-CNN Models for Real-time Flood Prediction in Red River of the North, USA
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1