可达龙制剂在不同心律失常中的临床应用。

Farmakologiia i toksikologiia Pub Date : 1991-05-01
A A Galstian, A G Zaraelian
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引用次数: 0

摘要

Cordaron(胺碘龙、安哥拉龙、阿特兰西尔、康迪尼尔、曲乐)是法国-比利时公司“Labaz”生产的一种药物。cordaron的一些药理学特性,特别是其增加房室交界处不应期的能力,以及阻碍心房和心室之间兴奋循环的异常通路影响反向兴奋机制的能力,为消除心律失常提供了有利条件。在苏联和外国作者的一些论文中,提出了cordaron治疗各种心律失常患者的结果,表明该药物具有相当高的抗心律失常有效性。它的致死剂量几乎不存在。副作用只有在长期治疗期间才会出现,停药后就会消失。
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[The clinical use of the preparation kordaron in different arrhythmias].

Cordaron (amiodaron, angoron, atlansil, cordinil, trangorax) is a drug produced by the French-Belgian firm "Labaz". Some pharmacological properties of cordaron and in particular its ability to increase the refractory period both of the atrioventricular junction and the abnormal pathway that hampers the circulation of excitation between the atria and ventricles influencing the mechanism of reverse excitation provide favourable conditions for elimination of arrhythmias. In a number of papers of the Soviet and foreign authors there are presented the results of cordaron treatment of patients with various cardiac rhythm disorders which indicate a fairly high antiarrhythmic effectiveness of the drug. Its lethal dose is practically absent. Side effects show up only during a prolonged therapy and disappear after the drug withdrawal.

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