Pidyastuti Pakaya, Rini Daud Supu, Multiani S. Latif
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摘要

非洲鲶鱼是淡水鱼中白蛋白含量高的一种,白蛋白在新细胞形成过程中起作用,因此,它可以帮助细胞生长的过程,并可以加速因切口而受损的皮肤细胞的愈合。本研究旨在了解非洲鲶鱼肉提取物对伤口愈合时间的影响,以及口服非洲鲶鱼提取物的剂量在伤口愈合过程中最能提供最佳效果。本研究为实验室实验研究,采用横断面研究设计,后验对照组设计,以20只大鼠为研究对象,分为25 ml剂量治疗组、50 ml、75 ml/200只grBB大鼠和阴性对照。宏观观察切口愈合情况,观察红肿程度,用尺测量切口长度。数据分析采用Kruskal walis检验和事后检验,分析结果显示阴性对照组与P1、P2、P3组差异有统计学意义(p<0.05)。这说明非洲鲶鱼肉提取物对伤口愈合有影响。P3组(75 ml提取物)对伤口愈合的影响大于P1组(50 ml提取物)和P2组(50 ml提取物)。
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The Effect of Giving Extract African Catfish Meat (Clarias Gariepinus) on the Length of Time for Cuts Healing Process among White Male Wistar Rats (Rattus norvegicus)
African catfish is one of the freshwater fish with high albumin which plays a role in the process of new cell formation, so that, it can help the process of cell growth and can accelerate the healing of damaged skin cells due to an incision. This study aims to find out the effect of giving extract African Catfish meat on the length of time for the cuts healing process and the dose of African catfish extract that can provide the best effect in the cut healing process is given orally. This research is a laboratory experimental study with a cross-sectional research design with a post-test only control group design using 20 white rats as research subjects which were divided into a 25 ml dose treatment group, 50 ml, and 75 ml/200 grBB rats and negative control. Observations of cuts healing were carried out macroscopically with the parameters of reduced redness and edema and measuring the length of the incision using a ruler. Data analysis used the Kruskal walis test and post hoc test, the results of the analysis showed that there was a significant difference (p<0.05) between the negative control group and the P1, P2, and P3 groups. This shows that African Catfish meat extract affects wound healing. The P3 group (75 ml extract) had more effect on the cuts healing process than the P1 group (50 ml extract) and the P2 group (50 ml extract).
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