新生儿低血糖的发生率和危险因素:一项前瞻性研究

Dr. Ashwin R Dangi, Dr. Jayant R Salvi
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引用次数: 0

摘要

背景和目的:已经观察到低血糖不会引起新生儿的健康问题。这是由于新生儿正在适应子宫外的生活。本研究旨在探讨半城市地区新生儿低血糖的发生率及危险因素。材料和方法:这是一项基于医院的前瞻性研究,于2021年1月至2021年6月在印度Visnagar的Nootan综合医院儿科进行。纳入了150名新生儿。用巴拉德评分法将她们分为四组胎龄。使用标准血糖仪测量母亲和新生儿的血糖。对母亲来说,是在分娩时测量的。对于新生儿,在出生后0、3、6、12和24小时进行测量。结果:随着母亲血糖升高,婴儿血糖降低,r=-0.18,但相关性无统计学意义(p> 0.05)。不同胎龄、不同时间点的血糖水平差异无统计学意义。随着母亲血糖升高,新生儿血糖降低。新生儿低血糖的重要危险因素是低段剖宫产(LSCS)、低胎龄(LGA)婴儿和小胎龄(SGA)婴儿、早产儿和足月后婴儿。但这些危险因素差异无统计学意义(p> 0.05)。结论:低血糖症在发展中国家的新生儿中非常普遍,新生儿的血糖水平差异很大。早产儿和足月儿、LSCS、LGA和SGA生儿更容易发生低血糖,需要进行血糖监测。
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Incidence and risk factors of hypoglycemia among neonates: A prospective study
Background and Aim: it has been observed that low levels of the blood glucose do not cause health issues in the neonates. This is due to the fact that the neonates are adjusting to the life outside the uterus. Present study was carried out to study incidence and risk factors of hypoglycemia among neonates in semi urban areas. Material and Methods: This was a hospital based prospective study performed at the Department of Pediatrics, Nootan general hospital NMCRC Visnagar, India January 2021 to June 2021. 150 neonates were included. Ballards score was used to divide them into four groups of gestational age. Standard glucometer was used to measure blood glucose in mothers and neonates. For mothers, it was measured at time of delivery. For neonates, it was measured at zero, three, six, twelve and twenty four hours of birth. Standard treatment protocol was followed for neonatal hypoglycemia Results: As the mother blood glucose increased the babies blood glucose decreased with r=-0.18 but this correlation was not found to be statistically significant ( p> 0.05). The differences in the blood glucose levels at different time points at different gestational ages were not found to be statistically significant. As maternal blood glucose increased, neonatal glucose decreased. Important risk factors found for hypoglycemia in neonates were being born by lower segment cesarean section (LSCS), low for gestational age (LGA) babies and small for gestational age (SGA) babies, pre-term and post term babies. But these risk factors were not found to be statistically significant ( p> 0.05). Conclusion: Hypoglycemia is surprisingly common among neonates in developing countries There was a wide variation of blood glucose levels in newborns. Preterm and post-term babies, babies delivered by LSCS, LGA and SGA babies were more prone for hypoglycemia requiring blood glucose monitoring.
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