M. Guta, K. Urga, A. Assefa, Hirut Lemma, G. Addis, N. Gemeda, Kidist Yirsaw, K. Mudi, D. Melaku
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引用次数: 3
摘要
尼罗刺槐果实和茎皮甲醇粗提物和氯仿、乙酸乙酯、正丁醇及甲醇萃取物的水组分Willd。德尔。采用标准琼脂稀释法对埃塞俄比亚腹泻致病菌(大肠杆菌、痢疾志贺氏菌和伤寒沙门氏菌)的抑菌活性进行了筛选。此外，还对小白鼠进行了醋酸乙酯果提取物的急性毒性实验。与标准抗生素(氯霉素和四环素)提取物和组分相比，nilotica的活性较低(P . A. nilotica)。关键词:金合欢;抗菌活性;粗提物;传统医学。埃塞俄比亚生物科学杂志Vol. 6 (1) 2007: pp. 4349
Antibacterial Activity and Acute Toxicity Study of Acacia nilotica
Methanol crude extract and chloroform, ethyl acetate, n-butanol and aqueous fractions of the methanolic extract of fruits and stem bark of Acacia nilotica (L.) Willd. ex Del. (Fabaceae) were screened for antibacterial activity of diarrhoea-causing bacterial species (Escherichia coli, Shigella dysenteriae and Salmonella typhi) in Ethiopia using standard agar dilution method. Oral acute toxicity studies were also carried out on mice with the ethyl acetate fruit fraction of A. nilotica . Compared with standard antibiotic (chloramphenicol and tetracycline) extracts and fractions, A. nilotica had low activity (P A. nilotica . showed lower activity (P Keywords : Acacia nilotica ; Antibacterial activity; Crude extract; Traditional medicine. Ethiopian Journal of Biological Sciences Vol. 6 (1) 2007: pp. 4349
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